| Missing value estimation methods for DNA microarrays O Troyanskaya, M Cantor, G Sherlock, P Brown, T Hastie, R Tibshirani, ... Bioinformatics 17 (6), 520-525, 2001 | 5372 | 2001 |
| Predicting effects of noncoding variants with deep learning–based sequence model J Zhou, OG Troyanskaya Nature methods 12 (10), 931-934, 2015 | 2786 | 2015 |
| The genetic landscape of a cell M Costanzo, A Baryshnikova, J Bellay, Y Kim, ED Spear, CS Sevier, ... science 327 (5964), 425-431, 2010 | 2626 | 2010 |
| Diversity of gene expression in adenocarcinoma of the lung ME Garber, OG Troyanskaya, K Schluens, S Petersen, Z Thaesler, ... Proceedings of the National Academy of Sciences 98 (24), 13784-13789, 2001 | 1683 | 2001 |
| A global genetic interaction network maps a wiring diagram of cellular function M Costanzo, B VanderSluis, EN Koch, A Baryshnikova, C Pons, G Tan, ... Science 353 (6306), aaf1420, 2016 | 1483 | 2016 |
| Understanding multicellular function and disease with human tissue-specific networks CS Greene, A Krishnan, AK Wong, E Ricciotti, RA Zelaya, ... Nature genetics 47 (6), 569-576, 2015 | 1002 | 2015 |
| Endothelial cell diversity revealed by global expression profiling JT Chi, HY Chang, G Haraldsen, FL Jahnsen, OG Troyanskaya, ... Proceedings of the National Academy of Sciences 100 (19), 10623-10628, 2003 | 988 | 2003 |
| A Bayesian framework for combining heterogeneous data sources for gene function prediction (in Saccharomyces cerevisiae) OG Troyanskaya, K Dolinski, AB Owen, RB Altman, D Botstein Proceedings of the National Academy of Sciences 100 (14), 8348-8353, 2003 | 827 | 2003 |
| Hierarchical multi-label prediction of gene function Z Barutcuoglu, RE Schapire, OG Troyanskaya Bioinformatics 22 (7), 830-836, 2006 | 718 | 2006 |
| Coordination of growth rate, cell cycle, stress response, and metabolic activity in yeast MJ Brauer, C Huttenhower, EM Airoldi, R Rosenstein, JC Matese, ... Molecular biology of the cell 19 (1), 352-367, 2008 | 705 | 2008 |
| Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry A Chi, C Huttenhower, LY Geer, JJ Coon, JEP Syka, DL Bai, ... Proceedings of the National Academy of Sciences 104 (7), 2193-2198, 2007 | 704 | 2007 |
| Deep learning sequence-based ab initio prediction of variant effects on expression and disease risk J Zhou, CL Theesfeld, K Yao, KM Chen, AK Wong, OG Troyanskaya Nature genetics 50 (8), 1171-1179, 2018 | 696 | 2018 |
| New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries N Shrine, AL Guyatt, AM Erzurumluoglu, VE Jackson, BD Hobbs, ... Nature genetics 51 (3), 481-493, 2019 | 560 | 2019 |
| Systemic and cell type-specific gene expression patterns in scleroderma skin ML Whitfield, DR Finlay, JI Murray, OG Troyanskaya, JT Chi, ... Proceedings of the National Academy of Sciences 100 (21), 12319-12324, 2003 | 535 | 2003 |
| Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder A Krishnan, R Zhang, V Yao, CL Theesfeld, AK Wong, A Tadych, ... Nature neuroscience 19 (11), 1454-1462, 2016 | 517 | 2016 |
| SynNotch-CAR T cells overcome challenges of specificity, heterogeneity, and persistence in treating glioblastoma JH Choe, PB Watchmaker, MS Simic, RD Gilbert, AW Li, NA Krasnow, ... Science translational medicine 13 (591), eabe7378, 2021 | 500 | 2021 |
| Gene expression patterns in ovarian carcinomas ME Schaner, DT Ross, G Ciaravino, T Sørlie, O Troyanskaya, M Diehn, ... Molecular biology of the cell 14 (11), 4376-4386, 2003 | 462 | 2003 |
| Quantitative analysis of fitness and genetic interactions in yeast on a genome scale A Baryshnikova, M Costanzo, Y Kim, H Ding, J Koh, K Toufighi, JY Youn, ... Nature methods 7 (12), 1017-1024, 2010 | 459 | 2010 |
| Nonparametric methods for identifying differentially expressed genes in microarray data OG Troyanskaya, ME Garber, PO Brown, D Botstein, RB Altman Bioinformatics 18 (11), 1454-1461, 2002 | 449 | 2002 |
| Variation in gene expression patterns in human gastric cancers X Chen, SY Leung, ST Yuen, KM Chu, J Ji, R Li, ASY Chan, S Law, ... Molecular biology of the cell 14 (8), 3208-3215, 2003 | 379 | 2003 |
Curtis HuttenhowerDepartment of Biostatistics, Harvard School of Public HealthVerified email at hsph.harvard.edu
