| Metformin reduces liver glucose production by inhibition of fructose-1-6-bisphosphatase RW Hunter, CC Hughey, L Lantier, EI Sundelin, M Peggie, E Zeqiraj, ... Nature medicine 24 (9), 1395-1406, 2018 | 348 | 2018 |
| Mass spectrometry-based microassay of 2H and 13C plasma glucose labeling to quantify liver metabolic fluxes in vivo CM Hasenour, ML Wall, DE Ridley, CC Hughey, FD James, ... American Journal of Physiology-Endocrinology and Metabolism 309 (2), E191-E203, 2015 | 90 | 2015 |
| 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo CM Hasenour, DE Ridley, CC Hughey, FD James, EP Donahue, ... Journal of Biological Chemistry 289 (9), 5950-5959, 2014 | 89 | 2014 |
| Enhanced cardiac protein glycosylation (O-GlcNAc) of selected mitochondrial proteins in rats artificially selected for low running capacity VL Johnsen, DD Belke, CC Hughey, DS Hittel, RT Hepple, LG Koch, ... Physiological genomics 45 (1), 17-25, 2013 | 75 | 2013 |
| Approach to assessing determinants of glucose homeostasis in the conscious mouse CC Hughey, DH Wasserman, RS Lee-Young, L Lantier Mammalian genome 25, 522-538, 2014 | 72 | 2014 |
| SIRT2 knockout exacerbates insulin resistance in high fat-fed mice L Lantier, AS Williams, CC Hughey, DP Bracy, FD James, MA Ansari, ... PloS one 13 (12), e0208634, 2018 | 66 | 2018 |
| Iatrogenic hyperinsulinemia, not hyperglycemia, drives insulin resistance in type 1 diabetes as revealed by comparison with GCK-MODY (MODY2) JM Gregory, TJ Smith, JC Slaughter, HR Mason, CC Hughey, MS Smith, ... Diabetes 68 (8), 1565-1576, 2019 | 65 | 2019 |
| Loss of hepatic AMP-activated protein kinase impedes the rate of glycogenolysis but not gluconeogenic fluxes in exercising mice CC Hughey, FD James, DP Bracy, EP Donahue, JD Young, B Viollet, ... Journal of Biological Chemistry 292 (49), 20125-20140, 2017 | 59 | 2017 |
| Differentiating short‐ and long‐term effects of diet in the obese mouse using 1H‐nuclear magnetic resonance metabolomics GE Duggan, DS Hittel, CC Hughey, A Weljie, HJ Vogel, J Shearer Diabetes, Obesity and Metabolism 13 (9), 859-862, 2011 | 49 | 2011 |
| Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates CC Hughey, E Trefts, DP Bracy, FD James, EP Donahue, DH Wasserman Journal of Biological Chemistry 293 (30), 11944-11954, 2018 | 48 | 2018 |
| Regulation and role of glycophagy in skeletal muscle energy metabolism TD Heden, LS Chow, CC Hughey, DG Mashek Autophagy 18 (5), 1078-1089, 2022 | 46 | 2022 |
| Integrating the contributions of mitochondrial oxidative metabolism to lipotoxicity and inflammation in NAFLD pathogenesis CC Hughey, P Puchalska, PA Crawford Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids, 159209, 2022 | 45 | 2022 |
| Respirometric oxidative phosphorylation assessment in saponin-permeabilized cardiac fibers CC Hughey, DS Hittel, VL Johnsen, J Shearer JoVE (Journal of Visualized Experiments), e2431, 2011 | 45 | 2011 |
| Hyperinsulinemic-euglycemic clamp in the conscious rat CC Hughey, DS Hittel, VL Johnsen, J Shearer JoVE (Journal of Visualized Experiments), e2432, 2011 | 43 | 2011 |
| Liver AMP-activated protein kinase is unnecessary for gluconeogenesis but protects energy state during nutrient deprivation CM Hasenour, DE Ridley, FD James, CC Hughey, EP Donahue, B Viollet, ... PLoS One 12 (1), e0170382, 2017 | 40 | 2017 |
| Perfusion controls muscle glucose uptake by altering the rate of glucose dispersion in vivo PM McClatchey, IM Williams, Z Xu, NA Mignemi, CC Hughey, ... American Journal of Physiology-Endocrinology and Metabolism 317 (6), E1022-E1036, 2019 | 39 | 2019 |
| Exercise training does not correct abnormal cardiac glycogen accumulation in the db/db mouse model of type 2 diabetes J Shearer, KD Ross, CC Hughey, VL Johnsen, DS Hittel, DL Severson American journal of physiology-endocrinology and metabolism 301 (1), E31-E39, 2011 | 39 | 2011 |
| Multitissue 2H/13C flux analysis reveals reciprocal upregulation of renal gluconeogenesis in hepatic PEPCK-C–knockout mice M Rahim, CM Hasenour, TK Bednarski, CC Hughey, DH Wasserman, ... JCI insight 6 (12), 2021 | 33 | 2021 |
| Mesenchymal stem cell transplantation for the infarcted heart: therapeutic potential for insulin resistance beyond the heart CC Hughey, L Ma, FD James, DP Bracy, Z Wang, DH Wasserman, ... Cardiovascular Diabetology 12 (1), 1-14, 2013 | 33 | 2013 |
| O-GlcNAc modification is associated with insulin sensitivity in the whole blood of healthy young adult males JP Myslicki, J Shearer, DS Hittel, CC Hughey, DD Belke Diabetology & metabolic syndrome 6, 1-5, 2014 | 30 | 2014 |
