| The regulation of the secondary metabolism of Streptomyces: new links and experimental advances GP Van Wezel, KJ McDowall Natural product reports 28 (7), 1311-1333, 2011 | 546 | 2011 |
| Structure of Escherichia coli RNase E catalytic domain and implications for RNA turnover AJ Callaghan, MJ Marcaida, JA Stead, KJ McDowall, WG Scott, BF Luisi Nature 437 (7062), 1187-1191, 2005 | 355 | 2005 |
| A+ U content rather than a particular nucleotide order determines the specificity of RNase E cleavage. KJ McDowall, S Lin-Chao, SN Cohen Journal of Biological Chemistry 269 (14), 10790-10796, 1994 | 328 | 1994 |
| Regulation of antibiotic production in Actinobacteria: new perspectives from the post-genomic era HU Van Der Heul, BL Bilyk, KJ McDowall, RF Seipke, GP Van Wezel Natural product reports 35 (6), 575-604, 2018 | 262 | 2018 |
| The N-terminal Domain of therneGene Product has RNase E Activity and is Non-overlapping with the Arginine-rich RNA-binding Site KJ McDowall, SN Cohen Journal of molecular biology 255 (3), 349-355, 1996 | 210 | 1996 |
| Transcriptional activation of the pathway‐specific regulator of the actinorhodin biosynthetic genes in Streptomyces coelicolor GC Uguru, KE Stephens, JA Stead, JE Towle, S Baumberg, KJ McDowall Molecular microbiology 58 (1), 131-150, 2005 | 205 | 2005 |
| Endonucleolytic initiation of mRNA decay in Escherichia coli AJ Carpousis, BF Luisi, KJ McDowall Progress in molecular biology and translational science 85, 91-135, 2009 | 189 | 2009 |
| Site-specific RNase E cleavage of oligonucleotides and inhibition by stem–loops KJ McDowall, VR Kaberdin, SW Wu, SN Cohen, S Lin-Chao Nature 374 (6519), 287-290, 1995 | 188 | 1995 |
| The CafA protein required for the 5′-maturation of 16 S rRNA is a 5′-end-dependent ribonuclease that has context-dependent broad sequence specificity MR Tock, AP Walsh, G Carroll, KJ McDowall Journal of Biological Chemistry 275 (12), 8726-8732, 2000 | 187 | 2000 |
| The endoribonucleolytic N-terminal half of Escherichia coli RNase E is evolutionarily conserved in Synechocystis sp. and other bacteria but not the C-terminal half … VR Kaberdin, A Miczak, JS Jakobsen, S Lin-Chao, KJ McDowall, ... Proceedings of the National Academy of Sciences 95 (20), 11637-11642, 1998 | 172 | 1998 |
| RNase E: still a wonderfully mysterious enzyme SN Cohen, KJ McDowall Molecular microbiology 23 (6), 1099-1106, 1997 | 171 | 1997 |
| Effects of nucleotide sequence on the specificity of rne-dependent and RNase E-mediated cleavages of RNA I encoded by the pBR322 plasmid. S Lin-Chao, TT Wong, KJ McDowall, SN Cohen Journal of Biological Chemistry 269 (14), 10797-10803, 1994 | 168 | 1994 |
| The ams-1 and rne-3071 temperature-sensitive mutations in the ams gene are in close proximity to each other and cause substitutions within a domain that resembles a product of … KJ McDOWALL, RG Hernandez, S Lin-Chao, SN Cohen Journal of bacteriology 175 (13), 4245-4249, 1993 | 161 | 1993 |
| Direct entry by RNase E is a major pathway for the degradation and processing of RNA in Escherichia coli JE Clarke, L Kime, D Romero A, KJ McDowall Nucleic acids research 42 (18), 11733-11751, 2014 | 116 | 2014 |
| The permease gene nagE2 is the key to N‐acetylglucosamine sensing and utilization in Streptomyces coelicolor and is subject to multi‐level control H Nothaft, S Rigali, B Boomsma, M Swiatek, KJ McDowall, GP Van Wezel, ... Molecular microbiology 75 (5), 1133-1144, 2010 | 112 | 2010 |
| Characterization of an oxytetracycline‐resistance gene, otrA, of Streptomyces rimosus D Doyle, KJ McDowall, MJ Butler, IS Hunter Molecular microbiology 5 (12), 2923-2933, 1991 | 103 | 1991 |
| Rapid cleavage of RNA by RNase E in the absence of 5′ monophosphate stimulation L Kime, SS Jourdan, JA Stead, A Hidalgo‐Sastre, KJ McDowall Molecular microbiology 76 (3), 590-604, 2010 | 101 | 2010 |
| Dietary zinc oxide affects the expression of genes associated with inflammation: transcriptome analysis in piglets challenged with ETEC K88 HR Sargeant, KJ McDowall, HM Miller, MA Shaw Veterinary immunology and immunopathology 137 (1-2), 120-129, 2010 | 94 | 2010 |
| Quaternary structure and catalytic activity of the Escherichia coli ribonuclease E amino-terminal catalytic domain AJ Callaghan, JG Grossmann, YU Redko, LL Ilag, MC Moncrieffe, ... Biochemistry 42 (47), 13848-13855, 2003 | 90 | 2003 |
| Translational activation by the noncoding RNA DsrA involves alternative RNase III processing in the rpoS 5′-leader A Resch, T Afonyushkin, TB Lombo, KJ McDowall, U Bläsi, VR Kaberdin RNA 14 (3), 454-459, 2008 | 77 | 2008 |
Gilles van WezelProfessor of Molecular Biotechnology at Leiden University; NIOO-KNAWVerified email at biology.leidenuniv.nl
