[go: up one dir, main page]

Follow
Margarita Tararina
Margarita Tararina
Postdoctoral Researcher, University of Pennsylvania
Verified email at sas.upenn.edu - Homepage
Title
Cited by
Cited by
Year
Targeted deletion of kynurenine 3-Monooxygenase in mice a new tool for studying kynurenine pathway metabolism in periphery and brain
F Giorgini, SY Huang, KV Sathyasaikumar, FM Notarangelo, ...
Journal of Biological Chemistry 288 (51), 36554-36566, 2013
1502013
Xanthurenic acid formation from 3-hydroxykynurenine in the mammalian brain: neurochemical characterization and physiological effects
KV Sathyasaikumar, M Tararina, HQ Wu, SA Neale, F Weisz, TE Salt, ...
Neuroscience 367, 85-97, 2017
562017
Bioinformatic Analysis of the Flavin-Dependent Amine Oxidase Superfamily: Adaptations for Substrate Specificity and Catalytic Diversity
MA Tararina, KN Allen
Journal of Molecular Biology, 2020
392020
Structural Analysis Provides Mechanistic Insight into Nicotine Oxidoreductase from Pseudomonas putida
MA Tararina, KD Janda, KN Allen
Biochemistry 55 (48), 6595-6598, 2016
372016
Crystallography coupled with kinetic analysis provides mechanistic underpinnings of a nicotine-degrading enzyme
MA Tararina, S Xue, LC Smith, SN Muellers, PO Miranda, KD Janda, ...
Biochemistry 57 (26), 3741-3751, 2018
332018
Development of First-in-Class Dual Sirt2/HDAC6 Inhibitors as Molecular Tools for Dual Inhibition of Tubulin Deacetylation
L Sinatra, A Vogelmann, F Friedrich, MA Tararina, E Neuwirt, A Colcerasa, ...
Journal of Medicinal Chemistry 66 (21), 14787-14814, 2023
302023
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A
L Lin, ME Olson, T Sugane, LD Turner, MA Tararina, AL Nielsen, ...
Journal of Medicinal Chemistry 63 (19), 11100-11120, 2020
282020
Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2
MA Tararina, KK Dam, M Dhingra, KD Janda, BA Palfey, KN Allen
Biochemistry 60 (4), 259-273, 2021
192021
2-Aminonicotinic acid 1-oxides are chemically stable inhibitors of quinolinic acid synthesis in the mammalian brain: a step toward new antiexcitotoxic agents
GP Vallerini, L Amori, C Beato, M Tararina, XD Wang, R Schwarcz, ...
Journal of medicinal chemistry 56 (23), 9482-9495, 2013
192013
Structural Insights into the Substrate Range of a Bacterial Monoamine Oxidase
SN Muellers, MA Tararina, U Kuzmanovic, JE Galagan, KN Allen
Biochemistry 62 (3), 851-862, 2023
92023
Structure of the Repurposed Fungal Terpene Cyclase FlvF Implicated in the C–N Bond-Forming Reaction of Flavunoidine Biosynthesis
MA Tararina, DA Yee, Y Tang, DW Christianson
Biochemistry 61 (18), 2014-2024, 2022
62022
Enzyme-based electrochemical nicotine biosensor
J Galagan, MW Grinstaff, U Kuzmanovic, C Mingfu, MA Tararina, KN Allen
US Patent 11,331,020, 2022
32022
Structural Analysis of a Non‐canonical Terpene Synthase
MA Tararina, DA Yee, Y Tang, DW Christianson
The FASEB Journal 36, 2022
2022
An Enzymatic Electrochemical Biosensor for Real-Time Detection of Physiologically Relevant Nicotine Concentrations
U Kuzmanovic, M Chen, M Tararina, N Shu, P Sensharma, A Gupta, ...
Electrochemical Society Meeting Abstracts prime2020, 3374-3374, 2020
2020
Structural and mechanistic analyses of a nicotine-degrading enzyme from Pseudomonas putida: towards design of tools and biotherapeutics
MA Tararina
Boston University, 2020
2020
An enzymatic electrochemical biosensor for real-time nicotine detection
U Kuzmanovic, M Chen, M Tararina, N Shu, A Balijepalli, M Zamani, ...
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 256, 2018
2018
Structure/Function Analysis of Pseudomonas putida Nicotine Oxidoreductase
M Tararina, S Xue, K Janda, K Allen
ACTA CRYSTALLOGRAPHICA A-FOUNDATION AND ADVANCES 73, A255-A255, 2017
2017
Kynurenine Pathway Metabolites as Modulators of Glutamatergic Neurotransmission
R Schwarcz, KV Sathyasaikumar, M Tararina, HQ Wu, DM Bortz, JP Bruno
CURRENT NEUROPHARMACOLOGY 12, 55-55, 2014
2014
The system can't perform the operation now. Try again later.
Articles 1–18