| A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin JG Menting, J Gajewiak, CA MacRaild, DHC Chou, MM Disotuar, ... Nature Structural & Molecular Biology, 2016 | 98 | 2016 |
| Fish-hunting cone snail venoms are a rich source of minimized ligands of the vertebrate insulin receptor P Ahorukomeye, MM Disotuar, J Gajewiak, S Karanth, M Watkins, ... Elife 8, e41574, 2019 | 71 | 2019 |
| BAK core dimers bind lipids and can be bridged by them AD Cowan, NA Smith, JJ Sandow, EA Kapp, YH Rustam, JM Murphy, ... Nature Structural & Molecular Biology 27 (11), 1024-1031, 2020 | 67 | 2020 |
| Identification of an activation site in Bak and mitochondrial Bax triggered by antibodies S Iyer, K Anwari, AE Alsop, WS Yuen, DCS Huang, J Carroll, NA Smith, ... Nature communications 7, 2016 | 67 | 2016 |
| A structurally minimized yet fully active insulin based on cone-snail venom insulin principles X Xiong, JG Menting, MM Disotuar, NA Smith, CA Delaine, G Ghabash, ... Nature structural & molecular biology 27 (7), 615-624, 2020 | 59 | 2020 |
| Structural insights into BCL2 pro-survival protein interactions with the key autophagy regulator BECN1 following phosphorylation by STK4/MST1 EF Lee, NA Smith, TP Soares da Costa, N Meftahi, S Yao, TJ Harris, ... Autophagy 15 (5), 785-795, 2019 | 49 | 2019 |
| Insulin mimetic peptide disrupts the primary binding site of the insulin receptor CF Lawrence, MB Margetts, JG Menting, NA Smith, BJ Smith, CW Ward, ... Journal of Biological Chemistry 291 (30), 15473-15481, 2016 | 43 | 2016 |
| Distinct activation modes of the Relaxin Family Peptide Receptor 2 in response to insulin-like peptide 3 and relaxin S Bruell, A Sethi, N Smith, DJ Scott, MA Hossain, QP Wu, ZY Guo, ... Scientific Reports 7 (1), 3294, 2017 | 24 | 2017 |
| Solution structure of an ultra-stable single-chain insulin analog connects protein dynamics to a novel mechanism of receptor binding MD Glidden, Y Yang, NA Smith, NB Phillips, K Carr, NP Wickramasinghe, ... Journal of Biological Chemistry 293 (1), 69-88, 2018 | 19 | 2018 |
| "Register-shift” insulin analogs uncover constraints of proteotoxicity in protein evolution NK Rege, M Liu, B Dhayalan, YS Chen, NA Smith, L Rahimi, J Sun, ... Journal of Biological Chemistry, jbc. RA119. 011389, 2020 | 14 | 2020 |
| Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis Z Yuan, MF van Delft, MX Li, F Sumardy, BJ Smith, DCS Huang, ... Plos Biology 22 (5), e3002617, 2024 | 8 | 2024 |
| Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation AY Robin, MS Miller, S Iyer, MX Shi, AZ Wardak, D Lio, NA Smith, ... Cell Death & Differentiation 29 (9), 1757-1768, 2022 | 6 | 2022 |
| Optimization of Benzothiazole and Thiazole Hydrazones as Inhibitors of Schistosome BCL-2 BES William Nguyen, Erinna F. Lee, Marco Evangelista, Mihwa Lee, Tiffany J ... ACS Infect. Dis., 2021 | 6 | 2021 |
| Structure of the Plasmodium falciparum PfSERA5 pseudo‐zymogen NA Smith, OB Clarke, M Lee, AN Hodder, BJ Smith Protein Science, 2020 | 6 | 2020 |
| Single-chain insulin analogs threaded by the insulin receptor αCT domain NA Smith, JG Menting, MA Weiss, MC Lawrence, BJ Smith Biophysical Journal 121 (21), 4063-4077, 2022 | 4 | 2022 |
| The Bak core dimer focuses triacylglycerides in the membrane NA Smith, AZ Wardak, AD Cowan, PM Colman, PE Czabotar, BJ Smith Biophysical Journal 121 (3), 347-360, 2022 | 3 | 2022 |
| Molecular definition of the BAK: VDAC2 interaction as a target to manipulate apoptosis Z Yuan, MF van Delft, MX Li, F Sumardy, BJ Smith, DCS Huang, ... bioRxiv, 2023.12. 13.571450, 2023 | | 2023 |
| Computational Studies of Insulin Structure and Function NA Smith La Trobe University., 2019 | | 2019 |
John MentingSenior Research Officer, WEHIVerified email at wehi.edu.au
