| Critical assessment of metagenome interpretation: the second round of challenges F Meyer, A Fritz, ZL Deng, D Koslicki, TR Lesker, A Gurevich, G Robertson, ... Nature methods 19 (4), 429-440, 2022 | 366 | 2022 |
| Cold adapted enzymes. AO Smalås, HK Leiros, V Os, NP Willassen Biotechnology annual review 6, 1-57, 2000 | 285 | 2000 |
| Cold adaption of enzymes: structural comparison between salmon and bovine trypsins AO Smalås, ES Heimstad, A Hordvik, NP Willassen, R Male Proteins: Structure, Function, and Bioinformatics 20 (2), 149-166, 1994 | 193 | 1994 |
| Trypsin specificity as elucidated by LIE calculations, X‐ray structures, and association constant measurements HKS Leiros, BO Brandsdal, OA Andersen, V Os, I Leiros, R Helland, ... Protein science 13 (4), 1056-1070, 2004 | 144 | 2004 |
| Temperature and pH sensitivity of trypsins from Atlantic salmon (Salmo salar) in comparison with bovine and porcine trypsin H Outzen, GI Berglund, AO Smalås, NP Willassen Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular …, 1996 | 139 | 1996 |
| The genome sequence of the fish pathogen Aliivibrio salmonicida strain LFI1238 shows extensive evidence of gene decay E Hjerde, MS Lorentzen, MTG Holden, K Seeger, S Paulsen, N Bason, ... BMC genomics 9 (1), 616, 2008 | 128 | 2008 |
| Structural comparison of psychrophilic and mesophilic trypsins: Elucidating the molecular basis of cold‐adaptation HK Schrøder Leiros, NP Willassen, AO Smalås European Journal of Biochemistry 267 (4), 1039-1049, 2000 | 124 | 2000 |
| Effects of probiotic supplementation on the gut microbiota and antibiotic resistome development in preterm infants E Esaiassen, E Hjerde, JP Cavanagh, T Pedersen, JH Andresen, ... Frontiers in pediatrics 6, 347, 2018 | 116 | 2018 |
| The MAR databases: development and implementation of databases specific for marine metagenomics T Klemetsen, IA Raknes, J Fu, A Agafonov, SV Balasundaram, G Tartari, ... Nucleic acids research 46 (D1), D692-D699, 2018 | 112 | 2018 |
| The structure of uracil-DNA glycosylase from Atlantic cod (Gadus morhua) reveals cold-adaptation features I Leiros, E Moe, O Lanes, AO Smalås, NP Willassen Biological Crystallography 59 (8), 1357-1365, 2003 | 92 | 2003 |
| The metagenomic data life-cycle: standards and best practices P Ten Hoopen, RD Finn, LA Bongo, E Corre, B Fosso, F Meyer, A Mitchell, ... GigaScience 6 (8), gix047, 2017 | 82 | 2017 |
| Comparative expression study to increase the solubility of cold adapted Vibrio proteins in Escherichia coli L Niiranen, S Espelid, CR Karlsen, M Mustonen, SM Paulsen, ... Protein expression and purification 52 (1), 210-218, 2007 | 81 | 2007 |
| A family of nuclear homing endonucleases S Johansen, TM Embley, NP Willassen Nucleic acids research 21 (18), 4405, 1993 | 77 | 1993 |
| Comparative studies of endonuclease I from cold‐adapted Vibrio salmonicida and mesophilic Vibrio cholerae B Altermark, L Niiranen, NP Willassen, AO Smalås, E Moe The FEBS journal 274 (1), 252-263, 2007 | 69 | 2007 |
| Residue determinants and sequence analysis of cold-adapted trypsins HK Schrøder Leiros, NP Willassen, AO Smalås Extremophiles 3 (3), 205-219, 1999 | 69 | 1999 |
| Co-cultivation and transcriptome sequencing of two co-existing fish pathogens Moritella viscosa and Aliivibrio wodanis E Hjerde, C Karlsen, H Sørum, J Parkhill, NP Willassen, NR Thomson BMC genomics 16 (1), 447, 2015 | 66 | 2015 |
| Effect of fish skin mucus on the soluble proteome of Vibrio salmonicida analysed by 2-D gel electrophoresis and tandem mass spectrometry ILU Ræder, SM Paulsen, AO Smalås, NP Willassen Microbial Pathogenesis 42 (1), 36-45, 2007 | 60 | 2007 |
| Biochemical characterization and structural analysis of a new cold-active and salt-tolerant esterase from the marine bacterium Thalassospira sp. C De Santi, HKS Leiros, A Di Scala, D de Pascale, B Altermark, ... Extremophiles 20 (3), 323-336, 2016 | 58 | 2016 |
| Presence of acyl‐homoserine lactones in 57 members of the Vibrionaceae family AA Purohit, JA Johansen, H Hansen, HKS Leiros, A Kashulin, C Karlsen, ... Journal of Applied Microbiology 115 (3), 835-847, 2013 | 56 | 2013 |
| Characterization of a cold-active and salt tolerant esterase identified by functional screening of Arctic metagenomic libraries C De Santi, B Altermark, MM Pierechod, L Ambrosino, D de Pascale, ... BMC biochemistry 17 (1), 1, 2016 | 55 | 2016 |