| Horizontal gene transfer can rescue prokaryotes from Muller’s ratchet: benefit of DNA from dead cells and population subdivision N Takeuchi, K Kaneko, EV Koonin G3: Genes, Genomes, Genetics 4 (2), 325-339, 2014 | 148 | 2014 |
| Multilevel selection in models of prebiotic evolution: compartments and spatial self-organization P Hogeweg, N Takeuchi Origins of Life and Evolution of the Biosphere 33 (4), 375-403, 2003 | 136 | 2003 |
| Nature and intensity of selection pressure on CRISPR-associated genes N Takeuchi, YI Wolf, KS Makarova, EV Koonin Journal of bacteriology 194 (5), 1216-1225, 2012 | 134 | 2012 |
| Multilevel selection in models of prebiotic evolution II: a direct comparison of compartmentalization and spatial self-organization N Takeuchi, P Hogeweg PLoS computational biology 5 (10), e1000542, 2009 | 131 | 2009 |
| Evolutionary dynamics of RNA-like replicator systems: a bioinformatic approach to the origin of life N Takeuchi, P Hogeweg Physics of Life Reviews 9 (3), 219-263, 2012 | 124 | 2012 |
| On the origin of DNA genomes: evolution of the division of labor between template and catalyst in model replicator systems N Takeuchi, P Hogeweg, EV Koonin PLoS computational biology 7 (3), e1002024, 2011 | 88 | 2011 |
| Error-threshold exists in fitness landscapes with lethal mutants N Takeuchi, P Hogeweg BMC Evolutionary Biology 7 (1), 15, 2007 | 84 | 2007 |
| Evolution of complexity in RNA-like replicator systems N Takeuchi, P Hogeweg Biology Direct 3 (1), 11, 2008 | 81 | 2008 |
| Phenotypic error threshold; additivity and epistasis in RNA evolution N Takeuchi, PH Poorthuis, P Hogeweg BMC Evolutionary Biology 5 (1), 9, 2005 | 74 | 2005 |
| The origin of a primordial genome through spontaneous symmetry breaking N Takeuchi, P Hogeweg, K Kaneko Nature communications 8 (1), 250, 2017 | 50 | 2017 |
| Slightly beneficial genes are retained by bacteria evolving DNA uptake despite selfish elements B van Dijk, P Hogeweg, HM Doekes, N Takeuchi Elife 9, e56801, 2020 | 48 | 2020 |
| Gene-specific selective sweeps in bacteria and archaea caused by negative frequency-dependent selection N Takeuchi, OX Cordero, EV Koonin, K Kaneko BMC biology 13 (1), 20, 2015 | 47 | 2015 |
| The role of complex formation and deleterious mutations for the stability of RNA-like replicator systems N Takeuchi, P Hogeweg Journal of molecular evolution 65 (6), 668-686, 2007 | 44 | 2007 |
| The origin of the central dogma through conflicting multilevel selection N Takeuchi, K Kaneko Proceedings of the Royal Society B 286, 20191359, 2019 | 26 | 2019 |
| Prophages and plasmids can display opposite trends in the types of accessory genes they carry N Takeuchi, S Hamada-Zhu, H Suzuki Proceedings of the Royal Society B 290 (2001), 20231088, 2023 | 25 | 2023 |
| Conceptualizing the origin of life in terms of evolution N Takeuchi, P Hogeweg, K Kaneko Philosophical Transactions of the Royal Society A: Mathematical, Physical …, 2017 | 24 | 2017 |
| Transposable elements promote the evolution of genome streamlining B van Dijk, F Bertels, L Stolk, N Takeuchi, PB Rainey Philosophical Transactions of the Royal Society B 377 (1842), 20200477, 2022 | 21 | 2022 |
| Stronger selection can slow down evolution driven by recombination on a smooth fitness landscape M Ueda, N Takeuchi, K Kaneko PLoS One 12 (8), e0183120, 2017 | 19 | 2017 |
| Evolutionarily stable disequilibrium: endless dynamics of evolution in a stationary population N Takeuchi, K Kaneko, P Hogeweg Proceedings of the Royal Society B: Biological Sciences 283 (1830), 20153109, 2016 | 19 | 2016 |
| The evolution of strand preference in simulated RNA replicators with strand displacement: implications for the origin of transcription N Takeuchi, L Salazar, AM Poole, P Hogeweg Biology Direct 3 (1), 33, 2008 | 19 | 2008 |
Kunihiko KanekoUniversity of Tokyo & Niels Bohr InstituteVerified email at complex.c.u-tokyo.ac.jp
