| Impairment of the ubiquitin-proteasome system by protein aggregation NF Bence, RM Sampat, RR Kopito Science 292 (5521), 1552-1555, 2001 | 2837 | 2001 |
| Aggresomes: a cellular response to misfolded proteins JA Johnston, CL Ward, RR Kopito The Journal of cell biology 143 (7), 1883-1898, 1998 | 2647 | 1998 |
| Aggresomes, inclusion bodies and protein aggregation RR Kopito Trends in cell biology 10 (12), 524-530, 2000 | 2471 | 2000 |
| Degradation of CFTR by the ubiquitin-proteasome pathway CL Ward, S Omura, RR Kopito Cell 83 (1), 121-127, 1995 | 1732 | 1995 |
| Misfolded proteins partition between two distinct quality control compartments D Kaganovich, R Kopito, J Frydman Nature 454 (7208), 1088-1095, 2008 | 1129 | 2008 |
| Prion-like transmission of protein aggregates in neurodegenerative diseases P Brundin, R Melki, R Kopito Nature reviews Molecular cell biology 11 (4), 301-307, 2010 | 1034 | 2010 |
| Subversion of cellular autophagosomal machinery by RNA viruses WT Jackson, TH Giddings Jr, MP Taylor, S Mulinyawe, M Rabinovitch, ... PLoS biology 3 (5), e156, 2005 | 989 | 2005 |
| HDAC6 and microtubules are required for autophagic degradation of aggregated huntingtin A Iwata, BE Riley, JA Johnston, RR Kopito Journal of Biological Chemistry 280 (48), 40282-40292, 2005 | 893 | 2005 |
| Protein misfolding in neurodegenerative diseases: implications and strategies P Sweeney, H Park, M Baumann, J Dunlop, J Frydman, R Kopito, ... Translational neurodegeneration 6 (1), 6, 2017 | 792 | 2017 |
| Formation of high molecular weight complexes of mutant Cu, Zn-superoxide dismutase in a mouse model for familial amyotrophic lateral sclerosis JA Johnston, MJ Dalton, ME Gurney, RR Kopito Proceedings of the National Academy of Sciences 97 (23), 12571-12576, 2000 | 752 | 2000 |
| Glycerol Reverses the Misfolding Phenotype of the Most Common Cystic Fibrosis Mutation (∗) S Sato, CL Ward, ME Krouse, JJ Wine, RR Kopito Journal of Biological Chemistry 271 (2), 635-638, 1996 | 675 | 1996 |
| OS-9 and GRP94 deliver mutant α1-antitrypsin to the Hrd1–SEL1L ubiquitin ligase complex for ERAD JC Christianson, TA Shaler, RE Tyler, RR Kopito Nature cell biology 10 (3), 272-282, 2008 | 674 | 2008 |
| ER quality control: the cytoplasmic connection RR Kopito Cell 88 (4), 427-430, 1997 | 667 | 1997 |
| Primary structure and transmembrane orientation of the murine anion exchange protein RR Kopito, HF Lodish Nature 316 (6025), 234-238, 1985 | 664 | 1985 |
| Intracellular turnover of cystic fibrosis transmembrane conductance regulator. Inefficient processing and rapid degradation of wild-type and mutant proteins. CL Ward, RR Kopito Journal of Biological Chemistry 269 (41), 25710-25718, 1994 | 648 | 1994 |
| Global impairment of the ubiquitin-proteasome system by nuclear or cytoplasmic protein aggregates precedes inclusion body formation EJ Bennett, NF Bence, R Jayakumar, RR Kopito Molecular cell 17 (3), 351-365, 2005 | 646 | 2005 |
| Global changes to the ubiquitin system in Huntington's disease EJ Bennett, TA Shaler, B Woodman, KY Ryu, TS Zaitseva, CH Becker, ... Nature 448 (7154), 704-708, 2007 | 622 | 2007 |
| Defining human ERAD networks through an integrative mapping strategy JC Christianson, JA Olzmann, TA Shaler, ME Sowa, EJ Bennett, ... Nature cell biology 14 (1), 93-105, 2012 | 601 | 2012 |
| Biosynthesis and degradation of CFTR RR Kopito Physiological reviews 79 (1), S167-S173, 1999 | 564 | 1999 |
| Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates PH Ren, JE Lauckner, I Kachirskaia, JE Heuser, R Melki, RR Kopito Nature cell biology 11 (2), 219-225, 2009 | 511 | 2009 |
James A. OlzmannUniversity of California, BerkeleyVerified email at berkeley.edu
