| De novo design of protein structure and function with RFdiffusion JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ... Nature 620 (7976), 1089-1100, 2023 | 2406* | 2023 |
| Scaffolding protein functional sites using deep learning J Wang, S Lisanza, D Juergens, D Tischer, JL Watson, KM Castro, ... Science 377 (6604), 387-394, 2022 | 542 | 2022 |
| De novo design of high-affinity binders of bioactive helical peptides S Vázquez Torres, PJY Leung, P Venkatesh, ID Lutz, F Hink, HH Huynh, ... Nature 626 (7998), 435-442, 2024 | 228* | 2024 |
| Atomically accurate de novo design of antibodies with RFdiffusion NR Bennett, JL Watson, RJ Ragotte, AJ Borst, DJL See, C Weidle, ... Nature, 1-11, 2025 | 206* | 2025 |
| Design of biologically active binary protein 2D materials AJ Ben-Sasson, JL Watson, W Sheffler, MC Johnson, A Bittleston, ... Nature 589 (7842), 468-473, 2021 | 155 | 2021 |
| Macromolecular condensation buffers intracellular water potential JL Watson, E Seinkmane, CT Styles, A Mihut, LK Krüger, KE McNally, ... Nature 623 (7988), 842-852, 2023 | 119 | 2023 |
| Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology A Stangherlin, JL Watson, DCS Wong, S Barbiero, A Zeng, E Seinkmane, ... Nature Communications 12 (1), 6035, 2021 | 66 | 2021 |
| De novo design of pH-responsive self-assembling helical protein filaments H Shen, EM Lynch, S Akkineni, JL Watson, J Decarreau, NP Bethel, ... Nature Nanotechnology 19 (7), 1016-1021, 2024 | 55 | 2024 |
| Zero‐shot mutation effect prediction on protein stability and function using RoseTTAFold S Mansoor, M Baek, D Juergens, JL Watson, D Baker Protein Science 32 (11), e4780, 2023 | 52* | 2023 |
| Diffusing protein binders to intrinsically disordered proteins C Liu, K Wu, H Choi, HL Han, X Zhang, JL Watson, G Ahn, JZ Zhang, ... Nature 644 (8077), 809-817, 2025 | 46 | 2025 |
| Protein stability buffers the cost of translation attenuation following eIF2α phosphorylation K Schneider, GM Nelson, JL Watson, J Morf, M Dalglish, LM Luh, A Weber, ... Cell reports 32 (11), 2020 | 29 | 2020 |
| High-efficacy subcellular micropatterning of proteins using fibrinogen anchors JL Watson, S Aich, B Oller-Salvia, AA Drabek, SC Blacklow, J Chin, ... Journal of Cell Biology 220 (2), e202009063, 2021 | 26 | 2021 |
| Synthetic Par polarity induces cytoskeleton asymmetry in unpolarized mammalian cells JL Watson, LK Krüger, AJ Ben-Sasson, A Bittleston, MN Shahbazi, ... Cell 186 (21), 4710-4727. e35, 2023 | 23 | 2023 |
| Protein design using structure-prediction networks: AlphaFold and RoseTTAFold as protein structure foundation models J Wang, JL Watson, SL Lisanza Cold Spring Harbor Perspectives in Biology 16 (7), a041472, 2024 | 22 | 2024 |
| Multiple-instance-learning-based detection of coeliac disease in histological whole-slide images J Denholm, BA Schreiber, SC Evans, OM Crook, A Sharma, JL Watson, ... Journal of Pathology Informatics 13, 100151, 2022 | 22 | 2022 |
| Improved protein binder design using β-pairing targeted RFdiffusion I Sappington, M Toul, DS Lee, SA Robinson, I Goreshnik, C McCurdy, ... Nature Communications, 2026 | 16 | 2026 |
| ANXA11 biomolecular condensates facilitate protein-lipid phase coupling on lysosomal membranes J Nixon-Abell, FS Ruggeri, S Qamar, TW Herling, MA Czekalska, Y Shen, ... Nature Communications 16 (1), 2814, 2025 | 13 | 2025 |
| MotifBench: A standardized protein design benchmark for motif-scaffolding problems Z Zheng, B Zhang, K Didi, KK Yang, J Yim, JL Watson, HF Chen, ... arXiv preprint arXiv:2502.12479, 2025 | 10 | 2025 |
| HEATR5B associates with dynein‐dynactin and promotes motility of AP1‐bound endosomal membranes V Madan, L Albacete‐Albacete, L Jin, P Scaturro, JL Watson, N Muschalik, ... The EMBO Journal 42 (23), e114473, 2023 | 10 | 2023 |
| Parametrically guided design of beta barrels and transmembrane nanopores using deep learning DE Kim, JL Watson, D Juergens, S Majumder, R Sonigra, SR Gerben, ... BioRxiv, 2024.07. 22.604663, 2025 | 9 | 2025 |
