| Interplay between partner and ligand facilitates the folding and binding of an intrinsically disordered protein JM Rogers, V Oleinikovas, SL Shammas, CT Wong, D De Sancho, ... Proceedings of the National Academy of Sciences 111 (43), 15420-15425, 2014 | 167 | 2014 |
| Mechanism of O2 diffusion and reduction in FeFe hydrogenases A Kubas, C Orain, D De Sancho, L Saujet, M Sensi, C Gauquelin, ... Nature chemistry 9 (1), 88-95, 2017 | 161 | 2017 |
| Molecular origins of internal friction effects on protein-folding rates D De Sancho, A Sirur, RB Best Nature communications 5 (1), 4307, 2014 | 137 | 2014 |
| Residue-specific α-helix propensities from molecular simulation RB Best, D de Sancho, J Mittal Biophysical Journal 102 (6), 1462-1467, 2012 | 136 | 2012 |
| Protein folding rates and stability: how much is there beyond size? D De Sancho, U Doshi, V Munoz Journal of the American Chemical Society 131 (6), 2074-2075, 2009 | 92 | 2009 |
| Modulation of an IDP binding mechanism and rates by helix propensity and non-native interactions: association of HIF1α with CBP D De Sancho, RB Best Mol. BioSyst. 8, 256 - 267, 2011 | 89 | 2011 |
| What is the time scale for α-helix nucleation? D De Sancho, RB Best Journal of the American Chemical Society 133 (17), 6809-6816, 2011 | 88 | 2011 |
| Integrated prediction of protein folding and unfolding rates from only size and structural class D De Sancho, V Muñoz Phys. Chem. Chem. Phys. 13, 17030-17043, 2011 | 77 | 2011 |
| Mechanical architecture and folding of E. coli type 1 pilus domains A Alonso-Caballero, J Schönfelder, S Poly, F Corsetti, D De Sancho, ... Nature communications 9 (1), 2758, 2018 | 74 | 2018 |
| The influence of disulfide bonds on the mechanical stability of proteins is context dependent A Manteca, Á Alonso-Caballero, M Fertin, S Poly, D De Sancho, ... Journal of Biological Chemistry 292 (32), 13374-13380, 2017 | 69 | 2017 |
| Dependence of internal friction on folding mechanism W Zheng, D De Sancho, T Hoppe, RB Best Journal of the American Chemical Society 137 (9), 3283-3290, 2015 | 65 | 2015 |
| An Abl-FBP17 mechanosensing system couples local plasma membrane curvature and stress fiber remodeling during mechanoadaptation A Echarri, DM Pavón, S Sánchez, M García-García, E Calvo, ... Nature communications 10 (1), 5828, 2019 | 55 | 2019 |
| Aerobic Damage to [FeFe]‐Hydrogenases: Activation Barriers for the Chemical Attachment of O2 A Kubas, D De Sancho, RB Best, J Blumberger Angewandte Chemie International Edition 53 (16), 4081-4084, 2014 | 51 | 2014 |
| Resurrection of efficient Precambrian endoglucanases for lignocellulosic biomass hydrolysis N Barruetabeña, B Alonso-Lerma, A Galera-Prat, N Joudeh, ... Communications Chemistry 2 (1), 76, 2019 | 48 | 2019 |
| Markov state models of protein misfolding A Sirur, D De Sancho, RB Best The Journal of Chemical Physics 144 (7), 2016 | 44 | 2016 |
| Folding kinetics and unfolded state dynamics of the GB1 hairpin from molecular simulation D De Sancho, J Mittal, RB Best Journal of Chemical Theory and Computation 9 (3), 1743-1753, 2013 | 42 | 2013 |
| Thermodynamics of Gō-type models for protein folding L Prieto, D de Sancho, A Rey The Journal of chemical physics 123 (15), 2005 | 42 | 2005 |
| Mechanochemical evolution of the giant muscle protein titin as inferred from resurrected proteins A Manteca, J Schönfelder, A Alonso-Caballero, MJ Fertin, ... Nature Structural & Molecular Biology, 2017 | 41 | 2017 |
| Phase separation in amino acid mixtures is governed by composition D De Sancho Biophysical Journal 121 (21), 4119-4127, 2022 | 39 | 2022 |
| The power of force: insights into the protein folding process using single-molecule force spectroscopy J Schönfelder, D De Sancho, R Perez-Jimenez Journal of molecular biology 428 (21), 4245-4257, 2016 | 39 | 2016 |
Robert BestSenior Investigator, National Institutes of HealthVerified email at helix.nih.gov
