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Luis A. Brito
Luis A. Brito
Beam Therapeutics
Verified email at beamtx.com
Title
Cited by
Cited by
Year
Optimization of lipid nanoparticles for intramuscular administration of mRNA vaccines
KJ Hassett, KE Benenato, E Jacquinet, A Lee, A Woods, O Yuzhakov, ...
Molecular therapy Nucleic acids 15, 1-11, 2019
9752019
Nonviral delivery of self-amplifying RNA vaccines
AJ Geall, A Verma, GR Otten, CA Shaw, A Hekele, K Banerjee, Y Cu, ...
Proceedings of the National Academy of Sciences 109 (36), 14604-14609, 2012
8692012
Preclinical and clinical demonstration of immunogenicity by mRNA vaccines against H10N8 and H7N9 influenza viruses
K Bahl, JJ Senn, O Yuzhakov, A Bulychev, LA Brito, KJ Hassett, ME Laska, ...
Molecular Therapy 25 (6), 1316-1327, 2017
7882017
Efficient targeting and activation of antigen-presenting cells in vivo after modified mRNA vaccine administration in rhesus macaques
F Liang, G Lindgren, A Lin, EA Thompson, S Ols, J Röhss, S John, ...
Molecular Therapy 25 (12), 2635-2647, 2017
4482017
A cationic nanoemulsion for the delivery of next-generation RNA vaccines
LA Brito, M Chan, CA Shaw, A Hekele, T Carsillo, M Schaefer, J Archer, ...
Molecular Therapy 22 (12), 2118-2129, 2014
4202014
Impact of lipid nanoparticle size on mRNA vaccine immunogenicity
KJ Hassett, J Higgins, A Woods, B Levy, Y Xia, CJ Hsiao, E Acosta, ...
Journal of Controlled Release 335, 237-246, 2021
3712021
Novel approaches for vaccine development
MS Gebre, LA Brito, LH Tostanoski, DK Edwards, A Carfi, DH Barouch
Cell 184 (6), 1589-1603, 2021
3682021
Rapidly produced SAM® vaccine against H7N9 influenza is immunogenic in mice
A Hekele, S Bertholet, J Archer, DG Gibson, G Palladino, LA Brito, ...
Emerging microbes & infections 2 (1), 1-7, 2013
2762013
Nucleic acid vaccines: prospects for non-viral delivery of mRNA vaccines
RP Deering, S Kommareddy, JB Ulmer, LA Brito, AJ Geall
Expert opinion on drug delivery 11 (6), 885-899, 2014
2602014
Commentary: acceptable levels of endotoxin in vaccine formulations during preclinical research
LA Brito, M Singh
Journal of pharmaceutical sciences 100 (1), 34-37, 2011
2582011
Self-amplifying mRNA vaccines
LA Brito, S Kommareddy, D Maione, Y Uematsu, C Giovani, FB Scorza, ...
Advances in genetics 89, 179-233, 2015
2232015
Vaccine adjuvant formulations: a pharmaceutical perspective
LA Brito, P Malyala, DT O’Hagan
Seminars in immunology 25 (2), 130-145, 2013
2162013
Designing and building the next generation of improved vaccine adjuvants
LA Brito, DT O'Hagan
Journal of Controlled Release 190, 563-579, 2014
2142014
Rational design of small molecules as vaccine adjuvants
TYH Wu, M Singh, AT Miller, E De Gregorio, F Doro, U D’Oro, ...
Science translational medicine 6 (263), 263ra160-263ra160, 2014
2132014
Potent immune responses in rhesus macaques induced by nonviral delivery of a self-amplifying RNA vaccine expressing HIV type 1 envelope with a cationic nanoemulsion
WM Bogers, H Oostermeijer, P Mooij, G Koopman, EJ Verschoor, D Davis, ...
The Journal of infectious diseases 211 (6), 947-955, 2015
2102015
Induction of broad-based immunity and protective efficacy by self-amplifying mRNA vaccines encoding influenza virus hemagglutinin
M Brazzoli, D Magini, A Bonci, S Buccato, C Giovani, R Kratzer, V Zurli, ...
Journal of virology 90 (1), 332-344, 2016
1772016
Overview of vaccine adjuvants: introduction, history, and current status
RR Shah, KJ Hassett, LA Brito
Vaccine adjuvants: methods and protocols, 1-13, 2016
1752016
Induction of robust B cell responses after influenza mRNA vaccination is accompanied by circulating hemagglutinin-specific ICOS+ PD-1+ CXCR3+ T follicular helper cells
G Lindgren, S Ols, F Liang, EA Thompson, A Lin, F Hellgren, K Bahl, ...
Frontiers in immunology 8, 1539, 2017
1592017
Methods for making pharmaceutical formulations comprising microparticles with improved dispersibility, suspendability or wettability
D Chickering, S Reese, S Narasimhan, J Straub, H Bernstein, D Altreuter, ...
US Patent App. 10/955,261, 2005
1362005
The impact of size on particulate vaccine adjuvants
RR Shah, DT O'Hagan, MM Amiji, LA Brito
Nanomedicine 9 (17), 2671-2681, 2014
1332014
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Articles 1–20