| CHARMM: the biomolecular simulation program BR Brooks, CL Brooks III, AD Mackerell Jr, L Nilsson, RJ Petrella, B Roux, ... Journal of computational chemistry 30 (10), 1545-1614, 2009 | 10197 | 2009 |
| Three key residues form a critical contact network in a protein folding transition state M Vendruscolo, E Paci, CM Dobson, M Karplus Nature 409 (6820), 641-645, 2001 | 510 | 2001 |
| Pulling geometry defines the mechanical resistance of a β-sheet protein DJ Brockwell, E Paci, RC Zinober, GS Beddard, PD Olmsted, DA Smith, ... Nature Structural & Molecular Biology 10 (9), 731-737, 2003 | 478 | 2003 |
| Small-world view of the amino acids that play a key role in protein folding M Vendruscolo, NV Dokholyan, E Paci, M Karplus Physical Review E 65 (6), 061910, 2002 | 460 | 2002 |
| Forced unfolding of fibronectin type 3 modules: an analysis by biased molecular dynamics simulations E Paci, M Karplus Journal of molecular biology 288 (3), 441-459, 1999 | 417 | 1999 |
| Allostery in its many disguises: from theory to applications SJ Wodak, E Paci, NV Dokholyan, IN Berezovsky, A Horovitz, J Li, ... Structure 27 (4), 566-578, 2019 | 391 | 2019 |
| Unfolding proteins by external forces and temperature: the importance of topology and energetics E Paci, M Karplus Proceedings of the National Academy of Sciences 97 (12), 6521-6526, 2000 | 357 | 2000 |
| Mechanical unfolding of a titin Ig domain: structure of unfolding intermediate revealed by combining AFM, molecular dynamics simulations, NMR and protein engineering SB Fowler, RB Best, JLT Herrera, TJ Rutherford, A Steward, E Paci, ... Journal of molecular biology 322 (4), 841-849, 2002 | 239 | 2002 |
| ORAC: A molecular dynamics program to simulate complex molecular systems with realistic electrostatic interactions P Procacci, TA Darden, E Paci, M Marchi Journal of computational chemistry 18 (15), 1848-1862, 1997 | 209 | 1997 |
| Mechanically unfolding the small, topologically simple protein L DJ Brockwell, GS Beddard, E Paci, DK West, PD Olmsted, DA Smith, ... Biophysical journal 89 (1), 506-519, 2005 | 204 | 2005 |
| Mechanical unfolding of a titin Ig domain: structure of transition state revealed by combining atomic force microscopy, protein engineering and molecular dynamics simulations RB Best, SB Fowler, JLT Herrera, A Steward, E Paci, J Clarke Journal of molecular biology 330 (4), 867-877, 2003 | 202 | 2003 |
| Pulling direction as a reaction coordinate for the mechanical unfolding of single molecules RB Best, E Paci, G Hummer, OK Dudko The Journal of Physical Chemistry B 112 (19), 5968-5976, 2008 | 165 | 2008 |
| Rare fluctuations of native proteins sampled by equilibrium hydrogen exchange M Vendruscolo, E Paci, CM Dobson, M Karplus Journal of the American Chemical Society 125 (51), 15686-15687, 2003 | 151 | 2003 |
| Mechanical resistance of proteins explained using simple molecular models DK West, DJ Brockwell, PD Olmsted, SE Radford, E Paci Biophysical journal 90 (1), 287-297, 2006 | 140 | 2006 |
| The remarkable mechanical strength of polycystin-1 supports a direct role in mechanotransduction JR Forman, S Qamar, E Paci, RN Sandford, J Clarke Journal of molecular biology 349 (4), 861-871, 2005 | 137 | 2005 |
| Mechanical unfolding of TNfn3: the unfolding pathway of a fnIII domain probed by protein engineering, AFM and MD simulation SP Ng, RWS Rounsevell, A Steward, CD Geierhaas, PM Williams, E Paci, ... Journal of molecular biology 350 (4), 776-789, 2005 | 136 | 2005 |
| Protein folding and the organization of the protein topology universe K Lindorff-Larsen, P Røgen, E Paci, M Vendruscolo, CM Dobson Trends in biochemical sciences 30 (1), 13-19, 2005 | 129 | 2005 |
| Determination of a transition state at atomic resolution from protein engineering data E Paci, M Vendruscolo, CM Dobson, M Karplus Journal of molecular biology 324 (1), 151-163, 2002 | 125 | 2002 |
| Transition states for protein folding have native topologies despite high structural variability K Lindorff-Larsen, M Vendruscolo, E Paci, CM Dobson Nature structural & molecular biology 11 (5), 443-449, 2004 | 114 | 2004 |
| Structures and relative free energies of partially folded states of proteins M Vendruscolo, E Paci, M Karplus, CM Dobson Proceedings of the National Academy of Sciences 100 (25), 14817-14821, 2003 | 111 | 2003 |
Michele VendruscoloProfessor of Biophysics, University of CambridgeVerified email at cam.ac.uk
