| Designer deletion strains derived from Saccharomyces cerevisiae S288C: A useful set of strains and plasmids for PCR‐mediated gene disruption and other … C Baker Brachmann, A Davies, GJ Cost, E Caputo, J Li, P Hieter, ... Yeast 14 (2), 115-132, 1998 | 4370 | 1998 |
| A TALE nuclease architecture for efficient genome editing JC Miller, S Tan, G Qiao, KA Barlow, J Wang, DF Xia, X Meng, ... Nature biotechnology 29 (2), 143-148, 2011 | 3174 | 2011 |
| Genetic engineering of human ES and iPS cells using TALE nucleases D Hockemeyer, H Wang, S Kiani, CS Lai, Q Gao, JP Cassady, GJ Cost, ... Nature biotechnology 29 (8), 731, 0 | 1661 | |
| Knockout rats via embryo microinjection of zinc-finger nucleases AM Geurts, GJ Cost, Y Freyvert, B Zeitler, JC Miller, VM Choi, SS Jenkins, ... Science 325 (5939), 433, 2009 | 1268 | 2009 |
| Knockout rats generated by embryo microinjection of TALENs L Tesson, C Usal, S Ménoret, E Leung, BJ Niles, S Remy, Y Santiago, ... Nature biotechnology 29 (8), 695-696, 2011 | 844 | 2011 |
| Human L1 element target‐primed reverse transcription in vitro GJ Cost, Q Feng, A Jacquier, JD Boeke The EMBO journal, 2002 | 619 | 2002 |
| Human l1 retrotransposition is associated with genetic instability in vivo DE Symer, C Connelly, ST Szak, EM Caputo, GJ Cost, G Parmigiani, ... Cell 110 (3), 327-338, 2002 | 547 | 2002 |
| Efficient generation of a biallelic knockout in pigs using zinc-finger nucleases J Hauschild, B Petersen, Y Santiago, AL Queisser, JW Carnwath, ... Proceedings of the National Academy of Sciences 108 (29), 12013-12017, 2011 | 506 | 2011 |
| Translating dosage compensation to trisomy 21 J Jiang, Y Jing, GJ Cost, JC Chiang, HJ Kolpa, AM Cotton, DM Carone, ... Nature 500 (7462), 296-300, 2013 | 462 | 2013 |
| Correction of the sickle cell disease mutation in human hematopoietic stem/progenitor cells MD Hoban, GJ Cost, MC Mendel, Z Romero, ML Kaufman, AV Joglekar, ... Blood, The Journal of the American Society of Hematology 125 (17), 2597-2604, 2015 | 410 | 2015 |
| Targeting of human retrotransposon integration is directed by the specificity of the L1 endonuclease for regions of unusual DNA structure GJ Cost, JD Boeke Biochemistry 37 (51), 18081-18093, 1998 | 297 | 1998 |
| Zinc-finger nuclease-driven targeted integration into mammalian genomes using donors with limited chromosomal homology SJ Orlando, Y Santiago, RC DeKelver, Y Freyvert, EA Boydston, ... Nucleic acids research 38 (15), e152-e152, 2010 | 276 | 2010 |
| Targeted genomic modification with partially single-stranded donor molecules GJ Cost, DM Guschin, F Urnov US Patent 9,255,259, 2016 | 262 | 2016 |
| Methods and compositions for treatment of a genetic condition A Conway, GJ Cost, R DeKelver, EJ Rebar, A Reik, F Urnov, J Wang, ... US Patent 9,873,894, 2018 | 250 | 2018 |
| In vivo cleavage of transgene donors promotes nuclease‐mediated targeted integration S Cristea, Y Freyvert, Y Santiago, MC Holmes, FD Urnov, PD Gregory, ... Biotechnology and bioengineering 110 (3), 871-880, 2013 | 241 | 2013 |
| Highly efficient deletion of FUT8 in CHO cell lines using zinc‐finger nucleases yields cells that produce completely nonfucosylated antibodies L Malphettes, Y Freyvert, J Chang, PQ Liu, E Chan, JC Miller, Z Zhou, ... Biotechnology and bioengineering 106 (5), 774-783, 2010 | 231 | 2010 |
| Sequence-directed DNA translocation by purified FtsK PJ Pease, O Levy, GJ Cost, J Gore, JL Ptacin, D Sherratt, C Bustamante, ... Science 307 (5709), 586-590, 2005 | 224 | 2005 |
| BAK and BAX deletion using zinc‐finger nucleases yields apoptosis‐resistant CHO cells GJ Cost, Y Freyvert, A Vafiadis, Y Santiago, JC Miller, E Rebar, ... Biotechnology and bioengineering 105 (2), 330-340, 2010 | 220 | 2010 |
| Targeted genomic modification with partially single-stranded donor molecules GJ Cost, DM Guschin, F Urnov US Patent 9,005,973, 2015 | 216 | 2015 |
| Generation of a triple‐gene knockout mammalian cell line using engineered zinc‐finger nucleases PQ Liu, EM Chan, GJ Cost, L Zhang, J Wang, JC Miller, DY Guschin, ... Biotechnology and bioengineering 106 (1), 97-105, 2010 | 158 | 2010 |
Xiangdong Meng, 孟祥栋Bio-Rad; Sangamo Bioscience, UMASS Medical SchoolVerified email at Bio-Rad.com
