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Janko Kos
Janko Kos
Professor of Biochemistry, Faculty of Pharmacy, University of Ljubljana
Verified email at ffa.uni-lj.si - Homepage
Title
Cited by
Cited by
Year
The 2.0 AX‐ray crystal structure of chicken egg white cystatin and its possible mode of interaction with cysteine proteinases.
W Bode, R Engh, D Musil, U Thiele, R Huber, A Karshikov, J Brzin, J Kos, ...
The EMBO journal 7 (8), 2593-2599, 1988
7921988
Targeting cancer cells using PLGA nanoparticles surface modified with monoclonal antibody
P Kocbek, N Obermajer, M Cegnar, J Kos, J Kristl
Journal of controlled release 120 (1-2), 18-26, 2007
5872007
Cysteine proteinases and their endogenous inhibitors: target proteins for prognosis, diagnosis and therapy in cancer
J Kos, TT Lah
Oncology reports 5 (6), 1349-1410, 1998
3841998
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
B Brus, U Kosak, S Turk, A Pislar, N Coquelle, J Kos, J Stojan, JP Colletier, ...
Journal of medicinal chemistry 57 (19), 8167-8179, 2014
3062014
Cysteine proteinase inhibitors stefin A, stefin B, and cystatin C in sera from patients with colorectal cancer: relation to prognosis
J Kos, M Krasovec, N Cimerman, HJ Nielsen, IJ Christensen, N Brünner
Clinical Cancer Research 6 (2), 505-511, 2000
2912000
Lysosomal cathepsins: structure, role in antigen processing and presentation, and cancer
V Turk, B Turk, G Gunčar, D Turk, J Kos
Advances in enzyme regulation 42, 285-303, 2002
2762002
Proteins of higher fungi–from forest to application
J Erjavec, J Kos, M Ravnikar, T Dreo, J Sabotič
Trends in biotechnology 30 (5), 259-273, 2012
2702012
Serum cystatin C, a potent inhibitor of cysteine proteinases, is elevated in asthmatic patients
N Cimerman, PM Brguljan, M Krašovec, S Šuškovič, J Kos
Clinica chimica acta 300 (1-2), 83-95, 2000
2702000
Cathepsins B, H, and L and their inhibitors stefin A and cystatin C in sera of melanoma patients.
J Kos, B Stabuc, A Schweiger, M Krasovec, N Cimerman, N Kopitar-Jerala, ...
Clinical cancer research: an official journal of the American Association …, 1997
2621997
Cystatins in immune system
Š Magister, J Kos
Journal of Cancer 4 (1), 45, 2012
2602012
Cysteine proteinases and their inhibitors in extracellular fluids: markers for diagnosis and prognosis in cancer
J Kos, B Werle, T Lah, N Brunner
The International journal of biological markers 15 (1), 84-89, 2000
2572000
Mechanism of inhibition of papain by chicken egg white cystatin: Inhibition constants of N-terminally truncated forms and cyanogen bromide fragments of the inhibitor
W Machleidt, U Thiele, B Laber, I Assfalg-Machleidt, A Esterl, G Wiegand, ...
FEBS letters 243 (2), 234-238, 1989
2371989
Microbial and fungal protease inhibitors—current and potential applications
J Sabotič, J Kos
Applied microbiology and biotechnology 93 (4), 1351-1375, 2012
2202012
Serum cystatin C, a new marker of glomerular filtration rate, is increased during malignant progression
J Kos, B S̆tabuc, N Cimerman, N Brunner
Clinical chemistry 44 (12), 2556-2557, 1998
2171998
Cysteine cathepsins (proteases)—on the main stage of cancer?
V Turk, J Kos, B Turk
Cancer cell 5 (5), 409-410, 2004
2072004
Prognostic significance of cathepsins B and L in primary human breast cancer.
JA Foekens, J Kos, HA Peters, M Krasovec, MP Look, N Cimerman, ...
Journal of clinical oncology 16 (3), 1013-1021, 1998
1851998
The magic of crystal structure-based inhibitor optimization: development of a butyrylcholinesterase inhibitor with picomolar affinity and in vivo activity
U Kosak, B Brus, D Knez, S Zakelj, J Trontelj, A Pislar, R Sink, M Jukic, ...
Journal of medicinal chemistry 61 (1), 119-139, 2018
1802018
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
U Košak, B Brus, D Knez, R Šink, S Žakelj, J Trontelj, A Pišlar, J Šlenc, ...
Scientific reports 6 (1), 39495, 2016
1802016
Intracellular and extracellular cathepsin B facilitate invasion of MCF-10A neoT cells through reconstituted extracellular matrix in vitro
A Premzl, V Zavašnik-Bergant, V Turk, J Kos
Experimental cell research 283 (2), 206-214, 2003
1802003
Regulation of the Activity of Lysosomal Cysteine Proteinases by pH-lnduced Inactivation and/or Endogenous Protein Inhibitors, Cystatins
B Turk, JG Bieth, I Björk, I Dolenc, D Turk, N Cimerman, J Kos, A Čolič, ...
Biological Chemistry 376 (4), 225-230, 1995
1771995
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Articles 1–20