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Haidai Hu, Ph.D.
Haidai Hu, Ph.D.
Assistant Professor, NNF Center for Protein Research, University of Copenhagen
Verified email at cpr.ku.dk - Homepage
Title
Cited by
Cited by
Year
Structure and function of stator units of the bacterial flagellar motor
M Santiveri, A Roa-Eguiara, C Kühne, N Wadhwa, H Hu, HC Berg, ...
Cell 183 (1), 244-257. e16, 2020
2512020
Structural basis of torque generation in the bi-directional bacterial flagellar motor
H Hu, M Santiveri, N Wadhwa, HC Berg, M Erhardt, NMI Taylor
Trends in biochemical sciences 47 (2), 160-172, 2022
742022
Structure and mechanism of the Zorya anti-phage defence system
H Hu, PF Popp, TCD Hughes, A Roa-Eguiara, NR Rutbeek, FJO Martin, ...
Nature 639 (8056), 1093-1101, 2025
512025
Structure of the type VI secretion phospholipase effector Tle1 provides insight into its hydrolysis and membrane targeting
H Hu, H Zhang, Z Gao, D Wang, G Liu, J Xu, K Lan, Y Dong
Biological Crystallography 70 (8), 2175-2185, 2014
492014
Electrostatics, proton sensor, and networks governing the gating transition in GLIC, a proton-gated pentameric ion channel
H Hu, K Ataka, A Menny, Z Fourati, L Sauguet, PJ Corringer, P Koehl, ...
Proceedings of the National Academy of Sciences 115 (52), E12172-E12181, 2018
432018
Structural basis for a bimodal allosteric mechanism of general anesthetic modulation in pentameric ligand-gated ion channels
Z Fourati, RJ Howard, SA Heusser, H Hu, RR Ruza, L Sauguet, E Lindahl, ...
Cell reports 23 (4), 993-1004, 2018
362018
Crystal structures of a pentameric ion channel gated by alkaline pH show a widely open pore and identify a cavity for modulation
H Hu, A Nemecz, C Van Renterghem, Z Fourati, L Sauguet, PJ Corringer, ...
Proceedings of the National Academy of Sciences 115 (17), E3959-E3968, 2018
362018
Ion selectivity and rotor coupling of the Vibrio flagellar sodium-driven stator unit
H Hu, PF Popp, M Santiveri, A Roa-Eguiara, Y Yan, FJO Martin, Z Liu, ...
Nature communications 14 (1), 4411, 2023
31*2023
Structural basis for allosteric transitions of a multidomain pentameric ligand-gated ion channel
H Hu, RJ Howard, U Bastolla, E Lindahl, M Delarue
Proceedings of the National Academy of Sciences 117 (24), 13437-13446, 2020
292020
Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric …
Á Nemecz, H Hu, Z Fourati, C Van Renterghem, M Delarue, PJ Corringer
PLoS Biology 15 (12), e2004470, 2017
292017
Genome-wide mapping of the binding sites and structural analysis of Kaposi's sarcoma-associated herpesvirus viral interferon regulatory factor 2 reveal that it is a dna-binding …
H Hu, J Dong, D Liang, Z Gao, L Bai, R Sun, H Hu, H Zhang, Y Dong, ...
Journal of virology 90 (3), 1158-1168, 2016
172016
Structural dynamics and determinants of 2-aminoadenine specificity in DNA polymerase DpoZ of vibriophage ϕVC8
D Czernecki, H Hu, F Romoli, M Delarue
Nucleic Acids Research 49 (20), 11974-11985, 2021
92021
Structural basis for recognition of the type VI spike protein VgrG3 by a cognate immunity protein
J Zhang, H Zhang, Z Gao, H Hu, C Dong, YH Dong
FEBS letters 588 (10), 1891-1898, 2014
92014
Ion-driven rotary membrane motors: from structure to function
FJO Martin, M Santiveri, H Hu, NMI Taylor
Current Opinion in Structural Biology 88, 102884, 2024
32024
Structural Details of an Allosteric Mechanism for Bimodal Anesthetic Modulation of Pentameric Ligand-Gated Ion Channels
RJ Howard, Z Fourati, SA Heusser, H Hu, RR Ruza, L Sauguet, E Lindahl, ...
Biophysical Journal 114 (3), 204a, 2018
12018
Uncommon features of a novel γ-proteobacterial pentameric ligand-gated ion channel revealed by its crystal structure
HD Hu, A Nemecz, Z Fourati, PJ Corringer, M Delarue
Biophysical Journal 112 (3), 321a, 2017
12017
Cloning, purification, crystallization and preliminary X-ray studies of the putative type VI secretion immunity protein Tli5 (PA5088) from Pseudomonas aeruginosa
Z Chen, Z Gao, H Hu, J Xu, H Zhang, Y Dong
Structural Biology and Crystallization Communications 70 (7), 903-905, 2014
12014
Structural and functional studies of pentameric ligand-gated ion channels from bacteria
H Hu
Université Pierre et Marie Curie-Paris VI, 2017
2017
Elucidating Proton Sensitivity and Activation in the Gloeobacter Violaceus Ligand-Gated Ion Channel
Á Nemecz, Z Fourati, H Hu, PJ Corringer, M Delarue
Biophysical Journal 110 (3), 456a, 2016
2016
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Articles 1–19