| A biological classification of Huntington's disease: the Integrated Staging System SJ Tabrizi, S Schobel, EC Gantman, A Mansbach, B Borowsky, ... The Lancet Neurology 21 (7), 632-644, 2022 | 294 | 2022 |
| The Database of Quantitative Cellular Signaling: management and analysis of chemical kinetic models of signaling networks S Sivakumaran, S Hariharaputran, J Mishra, US Bhalla Bioinformatics 19 (3), 408-415, 2003 | 170 | 2003 |
| Correlated network activity enhances synaptic efficacy via BDNF and the ERK pathway at immature CA3–CA1 connections in the hippocampus MH Mohajerani, S Sivakumaran, P Zacchi, P Aguilera, E Cherubini Proceedings of the National Academy of Sciences 104 (32), 13176-13181, 2007 | 122 | 2007 |
| Selective Inhibition of KCC2 Leads to Hyperexcitability and Epileptiform Discharges in Hippocampal Slices and In Vivo S Sivakumaran, C R, M J, K M, S L, M DH, M J, M Y, M R, D M, B NJ, D J, ... The Journal of Neuroscience 35 (21), 8291-8296, 2015 | 121 | 2015 |
| Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities S Ikezu, H Yeh, JC Delpech, ME Woodbury, AA Van Enoo, Z Ruan, ... Molecular psychiatry 26 (6), 1808-1831, 2021 | 94 | 2021 |
| At immature mossy-fiber–CA3 synapses, correlated presynaptic and postsynaptic activity persistently enhances GABA release and network excitability via BDNF and cAMP-dependent PKA S Sivakumaran, MH Mohajerani, E Cherubini Journal of Neuroscience 29 (8), 2637-2647, 2009 | 94 | 2009 |
| Bumetanide reduces seizure progression and the development of pharmacoresistant status epilepticus S Sivakumaran, J Maguire Epilepsia 57 (2), 222-232, 2016 | 86 | 2016 |
| Depolarizing actions of GABA in immature neurons depend neither on ketone bodies nor on pyruvate R Tyzio, C Allene, R Nardou, MA Picardo, S Yamamoto, S Sivakumaran, ... Journal of Neuroscience 31 (1), 34-45, 2011 | 70 | 2011 |
| BDNF is required for seizure-induced but not developmental up-regulation of KCC2 in the neonatal hippocampus Puskarjov M, Ahmad F, Khirug S, Sudhir Sivakumaran, Kaila K, Blaesse P Neuropharmacology, 2014 | 66* | 2014 |
| PrPC controls via protein kinase A the direction of synaptic plasticity in the immature hippocampus MD Caiati, VF Safiulina, G Fattorini, S Sivakumaran, G Legname, ... Journal of Neuroscience 33 (7), 2973-2983, 2013 | 64 | 2013 |
| In the developing rat hippocampus, endogenous activation of presynaptic kainate receptors reduces GABA release from mossy fiber terminals MD Caiati, S Sivakumaran, E Cherubini Journal of Neuroscience 30 (5), 1750-1759, 2010 | 48 | 2010 |
| Volumetric MRI-based biomarkers in Huntington's disease: an evidentiary review KM Kinnunen, AJ Schwarz, EC Turner, D Pustina, EC Gantman, ... Frontiers in Neurology 12, 712555, 2021 | 43 | 2021 |
| Control of GABA release at mossy fiber-CA3 connections in the developing hippocampus VF Safiulina, MD Caiati, S Sivakumaran, G Bisson, M Migliore, ... Frontiers in Synaptic Neuroscience 2 (1), 2010 | 39 | 2010 |
| Ca2+‐independent phospholipase A2‐dependent sustained Rho‐kinase activation exhibits all‐or‐none response A Maeda, Y Ozaki, S Sivakumaran, T Akiyama, H Urakubo, A Usami, ... Genes to Cells 11 (9), 1071-1083, 2006 | 37 | 2006 |
| Effective data sharing as a conduit for advancing medical product development SR Karpen, JK White, AP Mullin, I O’Doherty, LD Hudson, K Romero, ... Therapeutic Innovation & Regulatory Science 55 (3), 591-600, 2021 | 32 | 2021 |
| Chemogenomic analysis reveals key role for lysine acetylation in regulating Arc stability J Lalonde, SA Reis, S Sivakumaran, CS Holland, H Wesseling, JF Sauld, ... Nature Communications 8 (1), 1659, 2017 | 32 | 2017 |
| Harmonizing tau positron emission tomography in Alzheimer's disease: The CenTauR scale and the joint propagation model A Leuzy, LL Raket, VL Villemagne, G Klein, M Tonietto, E Olafson, ... Alzheimer's & Dementia 20 (9), 5833-5848, 2024 | 30 | 2024 |
| Co-existence and co-release of classical neurotransmitters R Gutierrez, A Fiechter, J Frank, PW Hawkes Springer, 2009 | 29 | 2009 |
| Transforming drug development for neurological disorders: proceedings from a multidisease area workshop D Stephenson, R Belfiore-Oshan, Y Karten, J Keavney, DK Kwok, ... Neurotherapeutics 20 (6), 1682-1691, 2023 | 23 | 2023 |
| Huntington’s Disease Regulatory Science Consortium (HD-RSC). A biological classification of Huntington’s disease: The Integrated Staging System SJ Tabrizi, S Schobel, EC Gantman, A Mansbach, B Borowsky, ... Lancet Neurol 21 (7), 632-44, 2022 | 22 | 2022 |
Klaus RomeroORCID: 0000-0002-8576-8638 Critical Path InstituteVerified email at c-path.org
