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Alexey Revenko
Alexey Revenko
Executive Director Oncology, IONIS Pharmaceuticals
Verified email at ionisph.com
Title
Cited by
Cited by
Year
The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells
T Gutschner, M Hämmerle, M Eißmann, J Hsu, Y Kim, G Hung, A Revenko, ...
Cancer research 73 (3), 1180-1189, 2013
18512013
AZD9150, a next-generation antisense oligonucleotide inhibitor of STAT3 with early evidence of clinical activity in lymphoma and lung cancer
D Hong, R Kurzrock, Y Kim, R Woessner, A Younes, J Nemunaitis, ...
Science translational medicine 7 (314), 314ra185-314ra185, 2015
5112015
Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding
AS Revenko, D Gao, JR Crosby, G Bhattacharjee, C Zhao, C May, ...
Blood, The Journal of the American Society of Hematology 118 (19), 5302-5311, 2011
2562011
Inhibition of the intrinsic coagulation pathway factor XI by antisense oligonucleotides: a novel antithrombotic strategy with lowered bleeding risk
H Zhang, EC Löwenberg, JR Crosby, AR MacLeod, C Zhao, D Gao, ...
Blood, The Journal of the American Society of Hematology 116 (22), 4684-4692, 2010
2502010
STAT3 antisense oligonucleotide AZD9150 in a subset of patients with heavily pretreated lymphoma: results of a phase 1b trial
MJ Reilley, P McCoon, C Cook, P Lyne, R Kurzrock, Y Kim, R Woessner, ...
Journal for immunotherapy of cancer 6 (1), 119, 2018
2472018
Targeting KRAS-dependent tumors with AZD4785, a high-affinity therapeutic antisense oligonucleotide inhibitor of KRAS
SJ Ross, AS Revenko, LL Hanson, R Ellston, A Staniszewska, N Whalley, ...
Science translational medicine 9 (394), eaal5253, 2017
2252017
Selective depletion of factor XI or factor XII with antisense oligonucleotides attenuates catheter thrombosis in rabbits
JW Yau, P Liao, JC Fredenburgh, AR Stafford, AS Revenko, BP Monia, ...
Blood, The Journal of the American Society of Hematology 123 (13), 2102-2107, 2014
2052014
ANCCA/ATAD2 overexpression identifies breast cancer patients with poor prognosis, acting to drive proliferation and survival of triple-negative cells through control of B-Myb …
EV Kalashnikova, AS Revenko, AT Gemo, NP Andrews, CG Tepper, ...
Cancer research 70 (22), 9402-9412, 2010
1952010
ANCCA, an estrogen-regulated AAA+ ATPase coactivator for ERα, is required for coregulator occupancy and chromatin modification
JX Zou, AS Revenko, LB Li, AT Gemo, HW Chen
Proceedings of the National Academy of Sciences 104 (46), 18067-18072, 2007
1892007
Antithrombotic effect of antisense factor XI oligonucleotide treatment in primates
JR Crosby, U Marzec, AS Revenko, C Zhao, D Gao, A Matafonov, ...
Arteriosclerosis, thrombosis, and vascular biology 33 (7), 1670-1678, 2013
1752013
Androgen-induced coactivator ANCCA mediates specific androgen receptor signaling in prostate cancer
JX Zou, L Guo, AS Revenko, CG Tepper, AT Gemo, HJ Kung, HW Chen
Cancer research 69 (8), 3339-3346, 2009
1742009
Asialoglycoprotein receptor 1 mediates productive uptake of N-acetylgalactosamine-conjugated and unconjugated phosphorothioate antisense oligonucleotides …
M Tanowitz, L Hettrick, A Revenko, GA Kinberger, TP Prakash, PP Seth
Nucleic acids research 45 (21), 12388-12400, 2017
1592017
Colon cancer growth and dissemination relies upon thrombin, stromal PAR-1, and fibrinogen
GN Adams, L Rosenfeldt, M Frederick, W Miller, D Waltz, K Kombrinck, ...
Cancer research 75 (19), 4235-4243, 2015
1472015
Chromatin loading of E2F-MLL complex by cancer-associated coregulator ANCCA via reading a specific histone mark
AS Revenko, EV Kalashnikova, AT Gemo, JX Zou, HW Chen
Molecular and cellular biology 30 (22), 5260-5272, 2010
1442010
New developments in anticoagulants: past, present and future
JI Weitz, J Harenberg
Thrombosis and haemostasis 117 (07), 1283-1288, 2017
1322017
Differential uptake, kinetics and mechanisms of intracellular trafficking of next-generation antisense oligonucleotides across human cancer cell lines
E Linnane, P Davey, P Zhang, S Puri, M Edbrooke, E Chiarparin, ...
Nucleic acids research 47 (9), 4375-4392, 2019
1192019
Depletion of coagulation factor XII ameliorates brain pathology and cognitive impairment in Alzheimer disease mice
ZL Chen, AS Revenko, P Singh, AR MacLeod, EH Norris, S Strickland
Blood, The Journal of the American Society of Hematology 129 (18), 2547-2556, 2017
922017
Direct control of cell cycle gene expression by proto-oncogene product ACTR, and its autoregulation underlies its transforming activity
MC Louie, AS Revenko, JX Zou, J Yao, HW Chen
Molecular and cellular biology 26 (10), 3810-3823, 2006
922006
Direct targeting of FOXP3 in Tregs with AZD8701, a novel antisense oligonucleotide to relieve immunosuppression in cancer
A Revenko, LS Carnevalli, C Sinclair, B Johnson, A Peter, M Taylor, ...
Journal for ImmunoTherapy of Cancer 10 (4), e003892, 2022
902022
Cellular uptake mediated by epidermal growth factor receptor facilitates the intracellular activity of phosphorothioate-modified antisense oligonucleotides
S Wang, N Allen, TA Vickers, AS Revenko, H Sun, X Liang, ST Crooke
Nucleic acids research 46 (7), 3579-3594, 2018
892018
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Articles 1–20