| Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data NT Gupta, JA Vander Heiden, M Uduman, D Gadala-Maria, G Yaari, ... Bioinformatics 31 (20), 3356-3358, 2015 | 930 | 2015 |
| Intratumoral dendritic cell–CD4+ T helper cell niches enable CD8+ T cell differentiation following PD-1 blockade in hepatocellular carcinoma A Magen, P Hamon, N Fiaschi, BY Soong, MD Park, R Mattiuz, E Humblin, ... Nature medicine 29 (6), 1389-1399, 2023 | 331 | 2023 |
| Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data G Yaari, JA Vander Heiden, M Uduman, D Gadala-Maria, N Gupta, ... Frontiers in immunology 4, 2013 | 283 | 2013 |
| Salmonella infection drives promiscuous B cell activation followed by extrafollicular affinity maturation R Di Niro, SJ Lee, JA Vander Heiden, RA Elsner, N Trivedi, JM Bannock, ... Immunity 43 (1), 120-131, 2015 | 260 | 2015 |
| Neoadjuvant cemiplimab for resectable hepatocellular carcinoma: a single-arm, open-label, phase 2 trial TU Marron, MI Fiel, P Hamon, N Fiaschi, E Kim, SC Ward, Z Zhao, J Kim, ... The lancet Gastroenterology & hepatology 7 (3), 219-229, 2022 | 229 | 2022 |
| Interleukin-10 from CD4+ follicular regulatory T cells promotes the germinal center response BJ Laidlaw, Y Lu, RA Amezquita, JS Weinstein, JA Vander Heiden, ... Sci Immunol 2 (16), eaan4767, 2017 | 199 | 2017 |
| Hierarchical Clustering Can Identify B Cell Clones with High Confidence in Ig Repertoire Sequencing Data NT Gupta, KD Adams, AW Briggs, SC Timberlake, F Vigneault, ... The Journal of Immunology 198 (6), 2489-2499, 2017 | 182 | 2017 |
| A framework for highly multiplexed dextramer mapping and prediction of T cell receptor sequences to antigen specificity W Zhang, PG Hawkins, J He, NT Gupta, J Liu, G Choonoo, SW Jeong, ... Science advances 7 (20), eabf5835, 2021 | 109 | 2021 |
| Neutralizing antibodies against West Nile virus identified directly from human B cells by single-cell analysis and next generation sequencing K Tsioris, NT Gupta, AO Ogunniyi, RM Zimnisky, F Qian, Y Yao, X Wang, ... Integrative Biology 7 (12), 1587-1597, 2015 | 94 | 2015 |
| DDX17 (P72), a Sox2 binding partner, promotes stem-like features conferred by Sox2 in a small cell population in estrogen receptor-positive breast cancer H Alqahtani, K Gopal, N Gupta, K Jung, A Alshareef, X Ye, F Wu, L Li, ... Cellular signalling 28 (2), 42-50, 2016 | 43 | 2016 |
| Cancer cell-derived type I interferons instruct tumor monocyte polarization D Kwart, J He, S Srivatsan, C Lett, J Golubov, EM Oswald, P Poon, X Ye, ... Cell Reports 41 (10), 2022 | 41 | 2022 |
| Endogenous retroviral proteins provide an immunodominant but not requisite antigen in a murine immunotherapy tumor model X Ye, JC Waite, A Dhanik, N Gupta, M Zhong, C Adler, E Malahias, M Ni, ... Oncoimmunology 9 (1), 1758602, 2020 | 33 | 2020 |
| Responsive population dynamics and wide seeding into the duodenal lamina propria of transglutaminase-2-specific plasma cells in celiac disease R Di Niro, O Snir, K Kaukinen, G Yaari, KEA Lundin, NT Gupta, ... Mucosal immunology 9 (1), 254-264, 2016 | 33 | 2016 |
| Molecular assessment of intratumoral immune cell subsets and potential mechanisms of resistance to odronextamab, a CD20× CD3 bispecific antibody, in patients with relapsed … J Brouwer-Visser, N Fiaschi, RP Deering, KJ Cygan, D Scott, S Jeong, ... Journal for Immunotherapy of Cancer 12 (3), e008338, 2024 | 24 | 2024 |
| Designing meaningful continuous representations of T cell receptor sequences with deep generative models AY Leary, D Scott, NT Gupta, JC Waite, D Skokos, GS Atwal, PG Hawkins Nature Communications 15 (1), 4271, 2024 | 19 | 2024 |
| Human CD4 cytotoxic T lymphocytes mediate potent tumor control in humanized immune system mice W Lin, V Singh, R Springer, G Choonoo, N Gupta, A Patel, D Frleta, ... Communications Biology 6 (1), 447, 2023 | 19 | 2023 |
| Absence of central tolerance in Aire-deficient mice synergizes with immune-checkpoint inhibition to enhance antitumor responses AA Benitez, S Khalil-Agüero, A Nandakumar, NT Gupta, W Zhang, ... Communications Biology 3 (1), 355, 2020 | 15 | 2020 |
| Intratumoral mregDC and CXCL13 T helper niches enable local differentiation of CD8 T cells following PD-1 blockade A Magen, P Hamon, N Fiaschi, L Troncoso, E Humblin, D D’souza, ... BioRxiv, 2022.06. 22.497216, 2022 | 14 | 2022 |
| VDJML: a file format with tools for capturing the results of inferring immune receptor rearrangements IT Toby, MK Levin, EA Salinas, S Christley, S Bhattacharya, F Breden, ... BMC bioinformatics 17 (Suppl 13), 333, 2016 | 13 | 2016 |
| LTβR Agonism Promotes Antitumor Immune Responses via Modulation of the Tumor Microenvironment D An, G Chen, WY Cheng, K Mohrs, C Adler, NT Gupta, GS Atwal, ... Cancer Research 84 (23), 3984-4001, 2024 | 11 | 2024 |
Steven H. KleinsteinProfessor, Departments of Pathology and Immunobiology, Yale School of MedicineVerified email at yale.edu
