| CRISPRdirect: software for designing CRISPR/Cas guide RNA with reduced off-target sites Y Naito, K Hino, H Bono, K Ui-Tei Bioinformatics 31 (7), 1120-1123, 2015 | 1399 | 2015 |
| Guidelines for the selection of highly effective siRNA sequences for mammalian and chick RNA interference K Ui‐Tei, Y Naito, F Takahashi, T Haraguchi, H Ohki‐Hamazaki, A Juni, ... Nucleic acids research 32 (3), 936-948, 2004 | 1156 | 2004 |
| siDirect: highly effective, target-specific siRNA design software for mammalian RNA interference Y Naito, T Yamada, K Ui-Tei, S Morishita, K Saigo Nucleic acids research 32 (suppl_2), W124-W129, 2004 | 377 | 2004 |
| Short-interfering-RNA-mediated gene silencing in mammalian cells requires Dicer and eIF2C translation initiation factors N Doi, S Zenno, R Ueda, H Ohki-Hamazaki, K Ui-Tei, K Saigo Current Biology 13 (1), 41-46, 2003 | 345 | 2003 |
| siDirect 2.0: updated software for designing functional siRNA with reduced seed-dependent off-target effect Y Naito, J Yoshimura, S Morishita, K Ui-Tei BMC bioinformatics 10 (1), 392, 2009 | 291 | 2009 |
| Sensitive assay of RNA interference in Drosophila and Chinese hamster cultured cells using firefly luciferase gene as target K Ui-Tei, S Zenno, Y Miyata, K Saigo FEBS letters 479 (3), 79-82, 2000 | 278 | 2000 |
| Human TNRC6A is an Argonaute-navigator protein for microRNA-mediated gene silencing in the nucleus K Nishi, A Nishi, T Nagasawa, K Ui-Tei Rna 19 (1), 17-35, 2013 | 251 | 2013 |
| Functional dissection of siRNA sequence by systematic DNA substitution: modified siRNA with a DNA seed arm is a powerful tool for mammalian gene silencing with significantly … K Ui-Tei, Y Naito, S Zenno, K Nishi, K Yamato, F Takahashi, A Juni, ... Nucleic acids research 36 (7), 2136-2151, 2008 | 242 | 2008 |
| Thermodynamic stability and Watson–Crick base pairing in the seed duplex are major determinants of the efficiency of the siRNA-based off-target effect K Ui-Tei, Y Naito, K Nishi, A Juni, K Saigo Nucleic acids research 36 (22), 7100-7109, 2008 | 236 | 2008 |
| dsCheck: highly sensitive off-target search software for double-stranded RNA-mediated RNA interference Y Naito, T Yamada, T Matsumiya, K Ui-Tei, K Saigo, S Morishita Nucleic acids research 33 (suppl_2), W589-W591, 2005 | 234 | 2005 |
| Formation of the male-specific muscle in female Drosophila by ectopic fruitless expression K Usui-Aoki, H Ito, K Ui-Tei, K Takahashi, T Lukacsovich, W Awano, ... Nature cell biology 2 (8), 500-506, 2000 | 201 | 2000 |
| New highly potent and specific E6 and E7 siRNAs for treatment of HPV16 positive cervical cancer K Yamato, T Yamada, M Kizaki, K Ui-Tei, Y Natori, M Fujino, T Nishihara, ... Cancer gene therapy 15 (3), 140-153, 2008 | 171 | 2008 |
| Aph-1 contributes to the stabilization and trafficking of the γ-secretase complex through mechanisms involving intermolecular and intramolecular interactions M Niimura, N Isoo, N Takasugi, M Tsuruoka, K Ui-Tei, K Saigo, ... Journal of Biological Chemistry 280 (13), 12967-12975, 2005 | 158 | 2005 |
| Heparan sulfate regulates self-renewal and pluripotency of embryonic stem cells N Sasaki, K Okishio, K Ui-Tei, K Saigo, A Kinoshita-Toyoda, H Toyoda, ... Journal of Biological Chemistry 283 (6), 3594-3606, 2008 | 146 | 2008 |
| LARK activates posttranscriptional expression of an essential mammalian clock protein, PERIOD1 S Kojima, K Matsumoto, M Hirose, M Shimada, M Nagano, Y Shigeyoshi, ... Proceedings of the National Academy of Sciences 104 (6), 1859-1864, 2007 | 130 | 2007 |
| Characterization of voltage-gated calcium currents in gonadotropin-releasing hormone neurons tagged with green fluorescent protein in rats M Kato, K Ui-Tei, M Watanabe, Y Sakuma Endocrinology 144 (11), 5118-5125, 2003 | 119 | 2003 |
| Dfrizzled-3, a new Drosophila Wnt receptor, acting as an attenuator of Wingless signaling in wingless hypomorphic mutants A Sato, T Kojima, K Ui-Tei, Y Miyata, K Saigo Development 126 (20), 4421-4430, 1999 | 117 | 1999 |
| Molecular cloning and characterization of a novel 3′-phosphoadenosine 5′-phosphosulfate transporter, PAPST2 S Kamiyama, N Sasaki, E Goda, K Ui-Tei, K Saigo, H Narimatsu, Y Jigami, ... Journal of Biological Chemistry 281 (16), 10945-10953, 2006 | 113 | 2006 |
| Stability of miRNA 5′ terminal and seed regions is correlated with experimentally observed miRNA-mediated silencing efficacy N Hibio, K Hino, E Shimizu, Y Nagata, K Ui-Tei Scientific reports 2 (1), 996, 2012 | 101 | 2012 |
| siRNA design software for a target gene-specific RNA interference Y Naito, K Ui-Tei Frontiers in genetics 3, 102, 2012 | 101 | 2012 |
