| Mechanism of activation of protein kinase JAK2 by the growth hormone receptor AJ Brooks, W Dai, ML O’Mara, D Abankwa, Y Chhabra, RA Pelekanos, ... Science 344 (6185), 1249783, 2014 | 495 | 2014 |
| Structural and thermodynamic analysis of the GFP: GFP‐nanobody complex MH Kubala, O Kovtun, K Alexandrov, BM Collins Protein Science 19 (12), 2389-2401, 2010 | 482 | 2010 |
| Rab GDP dissociation inhibitor as a general regulator for the membrane association of rab proteins. O Ullrich, H Stenmark, K Alexandrov, LA Huber, K Kaibuchi, T Sasaki, ... Journal of Biological Chemistry 268 (24), 18143-18150, 1993 | 425 | 1993 |
| GTPase activity of Rab5 acts as a timer for endocytic membrane fusion V Rybin, O Ullrich, M Rubino, K Alexandrov, I Simon, MC Seabra, ... Nature 383 (6597), 266-269, 1996 | 401 | 1996 |
| Rab escort protein‐1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes. K Alexandrov, H Horiuchi, O Steele‐Mortimer, MC Seabra, M Zerial The EMBO journal 13 (22), 5262-5273, 1994 | 352 | 1994 |
| The conserved lysine of the catalytic domain of protein kinases is actively involved in the phosphotransfer reaction and not required for anchoring ATP. AC Carrera, K Alexandrov, TM Roberts Proceedings of the National Academy of Sciences 90 (2), 442-446, 1993 | 298 | 1993 |
| Structure of Rab GDP-dissociation inhibitor in complex with prenylated YPT1 GTPase A Rak, O Pylypenko, T Durek, A Watzke, S Kushnir, L Brunsveld, ... Science 302 (5645), 646-650, 2003 | 264 | 2003 |
| Structure of the Rab7: REP-1 complex: insights into the mechanism of Rab prenylation and choroideremia disease A Rak, O Pylypenko, A Niculae, K Pyatkov, RS Goody, K Alexandrov Cell 117 (6), 749-760, 2004 | 223 | 2004 |
| Analysis of the eukaryotic prenylome by isoprenoid affinity tagging UTT Nguyen, Z Guo, C Delon, Y Wu, C Deraeve, B Fränzel, RS Bon, ... Nature Chemical Biology 5 (4), 227-235, 2009 | 219 | 2009 |
| Non-pathogenic trypanosomatid protozoa as a platform for protein research and production R Breitling, S Klingner, N Callewaert, R Pietrucha, A Geyer, G Ehrlich, ... Protein expression and purification 25 (2), 209-218, 2002 | 216 | 2002 |
| The structural and mechanistic basis for recycling of Rab proteins between membrane compartments RS Goody, A Rak, K Alexandrov Cellular and Molecular Life Sciences CMLS 62 (15), 1657-1670, 2005 | 211 | 2005 |
| Diels–Alder ligation and surface immobilization of proteins AD De Araújo, JM Palomo, J Cramer, M Köhn, H Schröder, R Wacker, ... Angewandte Chemie International Edition 45 (2), 296-301, 2006 | 206 | 2006 |
| Synthetic protein switches: design principles and applications V Stein, K Alexandrov Trends in biotechnology 33 (2), 101-110, 2015 | 193 | 2015 |
| Structure of Rab escort protein-1 in complex with Rab geranylgeranyltransferase O Pylypenko, A Rak, R Reents, A Niculae, V Sidorovitch, MD Cioaca, ... Molecular cell 11 (2), 483-494, 2003 | 192 | 2003 |
| Site‐selective protein immobilization by Staudinger ligation A Watzke, M Köhn, M Gutierrez‐Rodriguez, R Wacker, H Schröder, ... Angewandte Chemie International Edition 45 (9), 1408-1412, 2006 | 187 | 2006 |
| Species-independent translational leaders facilitate cell-free expression S Mureev, O Kovtun, UTT Nguyen, K Alexandrov Nature biotechnology 27 (8), 747-752, 2009 | 185 | 2009 |
| Single-molecule analysis reveals self assembly and nanoscale segregation of two distinct cavin subcomplexes on caveolae Y Gambin, N Ariotti, KA McMahon, M Bastiani, E Sierecki, O Kovtun, ... elife 3, e01434, 2014 | 176 | 2014 |
| Lipidated ras and rab peptides and proteins—synthesis, structure, and function L Brunsveld, J Kuhlmann, K Alexandrov, A Wittinghofer, RS Goody, ... Angewandte Chemie International Edition 45 (40), 6622-6646, 2006 | 164 | 2006 |
| Membrane targeting mechanism of Rab GTPases elucidated by semisynthetic protein probes YW Wu, LK Oesterlin, KT Tan, H Waldmann, K Alexandrov, RS Goody Nature chemical biology 6 (7), 534-540, 2010 | 157 | 2010 |
| Structure of doubly prenylated Ypt1: GDI complex and the mechanism of GDI‐mediated Rab recycling O Pylypenko, A Rak, T Durek, S Kushnir, BE Dursina, NH Thomae, ... The EMBO journal 25 (1), 13-23, 2006 | 155 | 2006 |
Roger GoodyProfessor Max-Planck-Institute, DortmundVerified email at mpi-dortmund.mpg.de
