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Guang Lu
Guang Lu
Verified email at sysu.edu.cn
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Year
Quercetin induces p53‐independent cancer cell death through lysosome activation by the transcription factor EB and reactive oxygen species‐dependent ferroptosis
ZX Wang, J Ma, XY Li, Y Wu, H Shi, Y Chen, G Lu, HM Shen, GD Lu, ...
British journal of pharmacology 178 (5), 1133-1148, 2021
2192021
PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1–Parkin-mediated mitophagy
L Wang, YL Cho, Y Tang, J Wang, JE Park, Y Wu, C Wang, Y Tong, ...
Cell research 28 (8), 787-802, 2018
2002018
Autophagy in health and disease: From molecular mechanisms to therapeutic target
G Lu, Y Wang, Y Shi, Z Zhang, C Huang, W He, C Wang, HM Shen
MedComm 3 (3), e150, 2022
1102022
A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery
HWS Tan, G Lu, H Dong, YL Cho, A Natalia, L Wang, C Chan, D Kappei, ...
Nature Communications 13 (1), 3720, 2022
1072022
HUWE1 interacts with BRCA1 and promotes its degradation in the ubiquitin–proteasome pathway
X Wang, G Lu, L Li, J Yi, K Yan, Y Wang, B Zhu, J Kuang, M Lin, S Zhang, ...
Biochemical and biophysical research communications 444 (4), 549-554, 2014
952014
Low dose of bisphenol a modulates ovarian cancer gene expression profile and promotes epithelial to mesenchymal transition via canonical wnt pathway
H Lin, H Li, G Lu, Z Chen, W Sun, Y Shi, Z Fu, B Huang, X Zhu, W Lu, ...
Toxicological Sciences 164 (2), 527-538, 2018
692018
PFKP alleviates glucose starvation-induced metabolic stress in lung cancer cells via AMPK-ACC2 dependent fatty acid oxidation
J Chen, L Zou, G Lu, O Grinchuk, L Fang, DST Ong, R Taneja, CN Ong, ...
Cell discovery 8 (1), 52, 2022
682022
Importance of ROS-mediated autophagy in determining apoptotic cell death induced by physapubescin B
J Xu, Y Wu, G Lu, S Xie, Z Ma, Z Chen, HM Shen, D Xia
Redox biology 12, 198-207, 2017
642017
Garciesculenxanthone B induces PINK1-Parkin-mediated mitophagy and prevents ischemia-reperfusion brain injury in mice
M Wu, G Lu, Y Lao, H Zhang, D Zheng, Z Zheng, J Yi, Q Xiang, L Wang, ...
Acta Pharmacologica Sinica 42 (2), 199-208, 2021
612021
Suppression of autophagy during mitosis via CUL4-RING ubiquitin ligases-mediated WIPI2 polyubiquitination and proteasomal degradation
G Lu, J Yi, A Gubas, YT Wang, Y Wu, Y Ren, M Wu, Y Shi, C Ouyang, ...
Autophagy 15 (11), 1917-1934, 2019
612019
EVA1A/TMEM166 regulates embryonic neurogenesis by autophagy
M Li, G Lu, J Hu, X Shen, J Ju, Y Gao, L Qu, Y Xia, Y Chen, Y Bai
Stem cell reports 6 (3), 396-410, 2016
532016
EMC6/TMEM93 suppresses glioblastoma proliferation by modulating autophagy
X Shen, S Kan, J Hu, M Li, G Lu, M Zhang, S Zhang, Y Hou, Y Chen, Y Bai
Cell death & disease 7 (1), e2043-e2043, 2016
502016
Knockout of Eva1a leads to rapid development of heart failure by impairing autophagy
S Zhang, X Lin, G Li, X Shen, D Niu, G Lu, X Fu, Y Chen, M Cui, Y Bai
Cell death & disease 8 (2), e2586-e2586, 2017
472017
The Long and the Short of PTEN in the Regulation of Mitophagy
L Wang, G Lu, HM Shen
Frontiers in Cell and Developmental Biology 8, 299, 2020
432020
EVA1A inhibits GBM cell proliferation by inducing autophagy and apoptosis
X Shen, S Kan, Z Liu, G Lu, X Zhang, Y Chen, Y Bai
Experimental cell research 352 (1), 130-138, 2017
432017
DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation
J Yi, G Lu, L Li, X Wang, L Cao, M Lin, S Zhang, G Shao
Nucleic acids research 43 (9), 4579-4590, 2015
432015
WIPI2 positively regulates mitophagy by promoting mitochondrial recruitment of VCP
G Lu, HWS Tan, T Schmauck-Medina, L Wang, J Chen, YL Cho, K Chen, ...
Autophagy 18 (12), 2865-2879, 2022
402022
Simultaneous treatment with sorafenib and glucose restriction inhibits hepatocellular carcinoma in vitro and in vivo by impairing SIAH1-mediated mitophagy
J Zhou, J Feng, Y Wu, HQ Dai, GZ Zhu, PH Chen, LM Wang, G Lu, ...
Experimental & Molecular Medicine 54 (11), 2007-2021, 2022
342022
Spautin-1 promotes PINK1-PRKN-dependent mitophagy and improves associative learning capability in an alzheimer disease animal model
J Yi, HL Wang, G Lu, H Zhang, L Wang, ZY Li, L Wang, Y Wu, D Xia, ...
Autophagy 20 (12), 2655-2676, 2024
312024
A destiny for degradation: interplay between cullin-RING E3 ligases and autophagy
G Lu, L Wang, J Zhou, W Liu, HM Shen
Trends in Cell Biology 31 (6), 432-444, 2021
282021
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