| Understanding the tumor immune microenvironment (TIME) for effective therapy M Binnewies, EW Roberts, K Kersten, V Chan, DF Fearon, M Merad, ... Nature medicine 24 (5), 541-550, 2018 | 5860 | 2018 |
| Imaging in the era of molecular oncology R Weissleder, MJ Pittet Nature 452 (7187), 580-589, 2008 | 2957 | 2008 |
| The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions M Nahrendorf, FK Swirski, E Aikawa, L Stangenberg, T Wurdinger, ... The Journal of experimental medicine 204 (12), 3037-3047, 2007 | 2835 | 2007 |
| Identification of splenic reservoir monocytes and their deployment to inflammatory sites FK Swirski, M Nahrendorf, M Etzrodt, M Wildgruber, V Cortez-Retamozo, ... Science 325 (5940), 612-616, 2009 | 2792 | 2009 |
| The intestinal microbiota modulates the anticancer immune effects of cyclophosphamide S Viaud, F Saccheri, G Mignot, T Yamazaki, R Daillère, D Hannani, ... science 342 (6161), 971-976, 2013 | 2322 | 2013 |
| Single-cell transcriptomics of human and mouse lung cancers reveals conserved myeloid populations across individuals and species R Zilionis, C Engblom, C Pfirschke, V Savova, D Zemmour, HD Saatcioglu, ... Immunity 50 (5), 1317-1334. e10, 2019 | 1541 | 2019 |
| Ly-6Chi monocytes dominate hypercholesterolemia-associated monocytosis and give rise to macrophages in atheromata FK Swirski, P Libby, E Aikawa, P Alcaide, FW Luscinskas, R Weissleder, ... The Journal of clinical investigation 117 (1), 195-205, 2007 | 1514 | 2007 |
| The spleen in local and systemic regulation of immunity V Bronte, MJ Pittet Immunity 39 (5), 806-818, 2013 | 1323 | 2013 |
| Myocardial infarction accelerates atherosclerosis P Dutta, G Courties, Y Wei, F Leuschner, R Gorbatov, CS Robbins, ... Nature 487 (7407), 325-329, 2012 | 1275 | 2012 |
| Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy A Sistigu, T Yamazaki, E Vacchelli, K Chaba, DP Enot, J Adam, I Vitale, ... Nature medicine 20 (11), 1301-1309, 2014 | 1217 | 2014 |
| Regulatory T cells suppress tumor-specific CD8 T cell cytotoxicity through TGF-β signals in vivo ML Chen, MJ Pittet, L Gorelik, RA Flavell, R Weissleder, H Von Boehmer, ... Proceedings of the National Academy of Sciences 102 (2), 419-424, 2005 | 1170 | 2005 |
| Successful anti-PD-1 cancer immunotherapy requires T cell-dendritic cell crosstalk involving the cytokines IFN-γ and IL-12 CS Garris, SP Arlauckas, RH Kohler, MP Trefny, S Garren, C Piot, ... Immunity 49 (6), 1148-1161. e7, 2018 | 1096 | 2018 |
| TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy CB Rodell, SP Arlauckas, MF Cuccarese, CS Garris, R Li, MS Ahmed, ... Nature biomedical engineering 2 (8), 578-588, 2018 | 1067 | 2018 |
| Immunogenic chemotherapy sensitizes tumors to checkpoint blockade therapy C Pfirschke, C Engblom, S Rickelt, V Cortez-Retamozo, C Garris, F Pucci, ... Immunity 44 (2), 343-354, 2016 | 1055 | 2016 |
| Monocytes: protagonists of infarct inflammation and repair after myocardial infarction M Nahrendorf, MJ Pittet, FK Swirski Circulation 121 (22), 2437-2445, 2010 | 1004 | 2010 |
| Therapeutic siRNA silencing in inflammatory monocytes in mice F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ... Nature biotechnology 29 (11), 1005-1010, 2011 | 948 | 2011 |
| Imaging macrophages with nanoparticles R Weissleder, M Nahrendorf, MJ Pittet Nature materials 13 (2), 125-138, 2014 | 919 | 2014 |
| The role of myeloid cells in cancer therapies C Engblom, C Pfirschke, MJ Pittet Nature Reviews Cancer 16 (7), 447-462, 2016 | 862 | 2016 |
| Origins of tumor-associated macrophages and neutrophils V Cortez-Retamozo, M Etzrodt, A Newton, PJ Rauch, A Chudnovskiy, ... Proceedings of the National Academy of Sciences 109 (7), 2491-2496, 2012 | 788 | 2012 |
| In vivo imaging reveals a tumor-associated macrophage–mediated resistance pathway in anti–PD-1 therapy SP Arlauckas, CS Garris, RH Kohler, M Kitaoka, MF Cuccarese, KS Yang, ... Science translational medicine 9 (389), eaal3604, 2017 | 716 | 2017 |
Ralph WeisslederProfessor, Harvard Medical SchoolVerified email at mgh.harvard.edu
