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| Lysine-specific demethylase 1 is strongly expressed in poorly differentiated neuroblastoma: implications for therapy JH Schulte, S Lim, A Schramm, N Friedrichs, J Koster, R Versteeg, I Ora, ... Cancer research 69 (5), 2065-2071, 2009 | 566 | 2009 |
| LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression JJ Molenaar, R Domingo-Fernández, ME Ebus, S Lindner, J Koster, ... Nature genetics 44 (11), 1199-1206, 2012 | 470 | 2012 |
| Mutational dynamics between primary and relapse neuroblastomas A Schramm, J Köster, Y Assenov, K Althoff, M Peifer, E Mahlow, ... Nature genetics 47 (8), 872-877, 2015 | 421 | 2015 |
| The miR-17-92 microRNA cluster regulates multiple components of the TGF-β pathway in neuroblastoma P Mestdagh, AK Boström, F Impens, E Fredlund, G Van Peer, ... Molecular cell 40 (5), 762-773, 2010 | 393 | 2010 |
| A mechanistic classification of clinical phenotypes in neuroblastoma S Ackermann, M Cartolano, B Hero, A Welte, Y Kahlert, A Roderwieser, ... Science 362 (6419), 1165-1170, 2018 | 379 | 2018 |
| Meta-analysis of neuroblastomas reveals a skewed ALK mutation spectrum in tumors with MYCN amplification S De Brouwer, K De Preter, C Kumps, P Zabrocki, M Porcu, ... Clinical cancer research 16 (17), 4353-4362, 2010 | 367 | 2010 |
| MYCN regulates oncogenic MicroRNAs in neuroblastoma JH Schulte, S Horn, T Otto, B Samans, LC Heukamp, UC Eilers, M Krause, ... International journal of cancer 122 (3), 699-704, 2008 | 325 | 2008 |
| Deep sequencing reveals differential expression of microRNAs in favorable versus unfavorable neuroblastoma JH Schulte, T Marschall, M Martin, P Rosenstiel, P Mestdagh, S Schlierf, ... Nucleic acids research 38 (17), 5919-5928, 2010 | 236 | 2010 |
| Lysine-specific demethylase 1 restricts hematopoietic progenitor proliferation and is essential for terminal differentiation A Sprüssel, JH Schulte, S Weber, M Necke, K Händschke, T Thor, ... Leukemia 26 (9), 2039-2051, 2012 | 232 | 2012 |
| Targeted expression of mutated ALK induces neuroblastoma in transgenic mice LC Heukamp, T Thor, A Schramm, K De Preter, C Kumps, B De Wilde, ... Science translational medicine 4 (141), 141ra91-141ra91, 2012 | 221 | 2012 |
| Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes K De Preter, J Vandesompele, P Heimann, N Yigit, S Beckman, ... Genome biology 7 (9), 1-17, 2006 | 209 | 2006 |
| Targeting MYCN-driven transcription by BET-bromodomain inhibition A Henssen, K Althoff, A Odersky, A Beckers, R Koche, F Speleman, ... Clinical Cancer Research 22 (10), 2470-2481, 2016 | 206 | 2016 |
| An integrative genomics screen uncovers ncRNA T-UCR functions in neuroblastoma tumours P Mestdagh, E Fredlund, F Pattyn, A Rihani, T Van Maerken, J Vermeulen, ... Oncogene 29 (24), 3583-3592, 2010 | 188 | 2010 |
| BET bromodomain protein inhibition is a therapeutic option for medulloblastoma A Henssen, T Thor, A Odersky, L Heukamp, N El-Hindy, A Beckers, ... Oncotarget 4 (11), 2080, 2013 | 184 | 2013 |
| Biological effects of TrkA and TrkB receptor signaling in neuroblastoma A Schramm, JH Schulte, K Astrahantseff, O Apostolov, V van Limpt, ... Cancer letters 228 (1-2), 143-153, 2005 | 180 | 2005 |
| The Phox2B homeobox gene is mutated in sporadic neuroblastomas V van Limpt, A Schramm, A Lakeman, P van Sluis, A Chan, M van Noesel, ... Oncogene 23 (57), 9280-9288, 2004 | 178 | 2004 |
| A Cre-conditional MYCN-driven neuroblastoma mouse model as an improved tool for preclinical studies K Althoff, A Beckers, E Bell, M Nortmeyer, T Thor, A Sprüssel, S Lindner, ... Oncogene 34 (26), 3357-3368, 2015 | 177 | 2015 |
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Jo Vandesompeleprofessor in functional cancer genomics and applied bioinformaticsVerified email at ugent.be
