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Bjarte Aarmo Lund
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Screening and design of inhibitor scaffolds for the antibiotic resistance oxacillinase-48 (OXA-48) through surface plasmon resonance screening
BA Lund, T Christopeit, Y Guttormsen, A Bayer, HKS Leiros
Journal of Medicinal Chemistry 59 (11), 5542-5554, 2016
402016
A focused fragment library targeting the antibiotic resistance enzyme-Oxacillinase-48: Synthesis, structural evaluation and inhibitor design
S Akhter, BA Lund, A Ismael, M Langer, J Isaksson, T Christopeit, ...
European journal of medicinal chemistry 145, 634-648, 2018
382018
Addressing the glycine‐rich loop of protein kinases by a multi‐facetted interaction network: inhibition of PKA and a PKB mimic
BS Lauber, LA Hardegger, AK Asraful, BA Lund, O Dumele, M Harder, ...
Chemistry–A European Journal 22 (1), 211-221, 2016
342016
Dissemination and characteristics of a novel plasmid-encoded carbapenem-hydrolyzing class D β-lactamase, OXA-436, found in isolates from four patients at six different …
Ø Samuelsen, F Hansen, B Aasnæs, H Hasman, BA Lund, HKS Leiros, ...
Antimicrobial Agents and Chemotherapy 62 (1), 10.1128/aac. 01260-17, 2018
332018
A high-throughput, restriction-free cloning and screening strategy based on ccd B-gene replacement
BA Lund, HKS Leiros, GEK Bjerga
Microbial Cell Factories 13 (1), 38, 2014
312014
Cryptic β-lactamase evolution is driven by low β-lactam concentrations
C Fröhlich, JA Gama, K Harms, VHA Hirvonen, BA Lund, ...
Msphere 6 (2), 10.1128/msphere. 00108-21, 2021
252021
Structure and mechanism of a cold-adapted bacterial lipase
F van der Ent, BA Lund, L Svalberg, M Purg, G Chukwu, M Widersten, ...
Biochemistry 61 (10), 933-942, 2022
212022
The biological assembly of OXA‐48 reveals a dimer interface with high charge complementarity and very high affinity
BA Lund, AM Thomassen, BHB Nesheim, TJO Carlsen, J Isaksson, ...
The FEBS Journal 285 (22), 4214-4228, 2018
202018
Computational design of the temperature optimum of an enzyme reaction
F van der Ent, S Skagseth, BA Lund, J Sočan, JJ Griese, BO Brandsdal, ...
Science Advances 9 (26), eadi0963, 2023
192023
Structure, activity and thermostability investigations of OXA-163, OXA-181 and OXA-245 using biochemical analysis, crystal structures and differential scanning calorimetry analysis
BA Lund, AM Thomassen, TJO Carlsen, HKS Leiros
Structural Biology and Crystallization Communications 73 (10), 579-587, 2017
162017
Structural origins of AGC protein kinase inhibitor selectivities: PKA as a drug discovery tool.
E Åberg, B Lund, A Pflug, OA Gani, U Rothweiler, TM de Oliveira, ...
Biological chemistry 393 (10), 2012
132012
Identification of fragments targeting SMYD3 using highly sensitive kinetic and multiplexed biosensor-based screening
EA FitzGerald, D Cederfelt, BA Lund, NEM Myers, H Zhang, D Dobritzsch, ...
RSC Medicinal Chemistry 15 (6), 1982-1990, 2024
102024
Regiodivergent Synthesis of 11H‐Indolo[3,2‐c]quinolines and Neocryptolepine from a Common Starting Material
KS Håheim, BA Lund, MO Sydnes
European Journal of Organic Chemistry 26 (13), e202300137, 2023
102023
Side‐Chain Interactions in d/l Peptide Nanotubes: Studies by Crystallography, NMR Spectroscopy and Molecular Dynamics
MR Silk, JR Price, B Mohanty, HKS Leiros, BA Lund, PE Thompson, ...
Chemistry–A European Journal 27 (58), 14489-14500, 2021
92021
Accurate computation of thermodynamic activation parameters in the chorismate mutase reaction from empirical valence bond simulations
RS Wilkins, BA Lund, GV Isaksen, J Åqvist, BO Brandsdal
Journal of Chemical Theory and Computation 20 (1), 451-458, 2023
72023
Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times
MP Sowiński, S Gahlawat, BA Lund, AL Warnke, KH Hopmann, JE Lovett, ...
Communications Chemistry 6 (1), 111, 2023
62023
Biochemical and biophysical characterization of the OXA-48-like carbapenemase OXA-436
BA Lund, AM Thomassen, TJW Carlsen, HKS Leiros
Structural Biology and Crystallization Communications 77 (9), 312-318, 2021
62021
The ambivalence of connexin43 Gap peptides in cardioprotection of the isolated heart against ischemic injury
AT Falck, BA Lund, D Johansen, T Lund, K Ytrehus
International Journal of Molecular Sciences 23 (17), 10197, 2022
52022
ThermoSlope: A software for determining thermodynamic parameters from single steady-state experiments
BA Lund, BO Brandsdal
Molecules 26 (23), 7155, 2021
42021
Computational Design of Highly Efficient Cold-Adapted Enzymes with Elevated Temperature Optima
F van der Ent, S Yu, BA Lund, BO Brandsdal, X Sheng, J Åqvist
ACS Catalysis 15, 11257-11265, 2025
22025
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Articles 1–20