| Chemical modifications designed to improve peptide stability: incorporation of non-natural amino acids, pseudo-peptide bonds, and cyclization L Gentilucci, R De Marco, L Cerisoli Current pharmaceutical design 16 (28), 3185-3203, 2010 | 720 | 2010 |
| Analytical pyrolysis of dipeptides containing proline and amino acids with polar side chains. Novel 2, 5-diketopiperazine markers in the pyrolysates of proteins D Fabbri, A Adamiano, G Falini, R De Marco, I Mancini Journal of analytical and applied pyrolysis 95, 145-155, 2012 | 137 | 2012 |
| Functional selectivity and antinociceptive effects of a novel KOPr agonist A Bedini, L Di Cesare Mannelli, L Micheli, M Baiula, G Vaca, R De Marco, ... Frontiers in pharmacology 11, 188, 2020 | 54 | 2020 |
| Peripheral antinociceptive effects of the cyclic endomorphin-1 analog c [YpwFG] in a mouse visceral pain model A Bedini, M Baiula, L Gentilucci, A Tolomelli, R De Marco, S Spampinato Peptides 31 (11), 2135-2140, 2010 | 50 | 2010 |
| Controlled Solid Phase Peptide Bond Formation Using N-Carboxyanhydrides and PEG Resins in Water. R De Marco, A Tolomelli, A Greco, L Gentilucci ACS Sustainable Chemistry & Engineering 1 (6), 566-569, 2013 | 43 | 2013 |
| Integrin ligands with α/β‐hybrid peptide structure: design, bioactivity, and conformational aspects R De Marco, A Tolomelli, E Juaristi, L Gentilucci Medicinal research reviews 36 (3), 389-424, 2016 | 40 | 2016 |
| Molecular docking of opiates and opioid peptides, a tool for the design of selective agonists and antagonists, and for the investigation of atypical ligand-receptor interactions L Gentilucci, A Tolomelli, R De Marco, R Artali Current medicinal chemistry 19 (11), 1587-1601, 2012 | 40 | 2012 |
| The Inverse Type II β‐Turn on D‐Trp‐Phe, a Pharmacophoric Motif for MOR Agonists L Gentilucci, A Tolomelli, R De Marco, S Spampinato, A Bedini, R Artali ChemMedChem 6 (9), 1640-1653, 2011 | 36 | 2011 |
| Synthesis of mixed MOR/KOR efficacy cyclic opioid peptide analogs with antinociceptive activity after systemic administration R Perlikowska, J Piekielna, L Gentilucci, R De Marco, MC Cerlesi, G Calo, ... European journal of medicinal chemistry 109, 276-286, 2016 | 34 | 2016 |
| Antiangiogenic Effect of Dual/Selective α5β1/αvβ3 Integrin Antagonists Designed on Partially Modified Retro-Inverso Cyclotetrapeptide Mimetics L Gentilucci, G Cardillo, S Spampinato, A Tolomelli, F Squassabia, ... Journal of medicinal chemistry 53 (1), 106-118, 2010 | 34 | 2010 |
| Diagnostic implementation of fast and selective integrin-mediated adhesion of cancer cells on functionalized zeolite L monolayers A Greco, L Maggini, L De Cola, R De Marco, L Gentilucci Bioconjugate Chemistry 26 (9), 1873-1878, 2015 | 32 | 2015 |
| DS‐70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs SD Dattoli, M Baiula, R De Marco, A Bedini, M Anselmi, L Gentilucci, ... British Journal of Pharmacology 175 (20), 3891-3910, 2018 | 30 | 2018 |
| Stimuli-responsive local drug molecule delivery to adhered cells in a 3D nanocomposite scaffold A Motealleh, R De Marco, NS Kehr Journal of Materials Chemistry B 7 (23), 3716-3723, 2019 | 28 | 2019 |
| Strategies to improve bioavailability and in vivo efficacy of the endogenous opioid peptides endomorphin-1 and endomorphin-2 R De Marco, A Janecka Current Topics in Medicinal Chemistry 16 (2), 141-155, 2016 | 28 | 2016 |
| Synthesis of Tripeptides Containing d-Trp Substituted at the Indole Ring, Assessment of Opioid Receptor Binding and in Vivo Central Antinociception R De Marco, A Bedini, S Spampinato, L Gentilucci Journal of Medicinal Chemistry 57 (15), 6861-6866, 2014 | 28 | 2014 |
| Expedient synthesis of pseudo-Pro-containing peptides: towards constrained peptidomimetics and foldamers R De Marco, A Tolomelli, M Campitiello, P Rubini, L Gentilucci Organic & Biomolecular Chemistry 10 (11), 2307-2317, 2012 | 26 | 2012 |
| Constraining endomorphin-1 by β, α-hybrid dipeptide/heterocycle scaffolds: identification of a novel κ-opioid receptor selective partial agonist R De Marco, A Bedini, S Spampinato, L Comellini, J Zhao, R Artali, ... Journal of Medicinal Chemistry 61 (13), 5751-5757, 2018 | 25 | 2018 |
| Versatile Picklocks To Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe-d-Pro-Phe-Trp] (CJ-15,208) R De Marco, A Bedini, S Spampinato, L Cavina, E Pirazzoli, L Gentilucci Journal of Medicinal Chemistry 59 (19), 9255-9261, 2016 | 22 | 2016 |
| Opioid activity profiles of oversimplified peptides lacking in the protonable N-terminus R De Marco, A Tolomelli, S Spampinato, A Bedini, L Gentilucci Journal of Medicinal Chemistry 55 (22), 10292-10296, 2012 | 21 | 2012 |
| A simple route towards peptide analogues containing substituted (S)-or (R)-tryptophans L Gentilucci, L Cerisoli, R De Marco, A Tolomelli Tetrahedron Letters 51 (19), 2576-2579, 2010 | 20 | 2010 |
