| Nucleic acid helix stability: effects of salt concentration, cation valence and size, and chain length ZJ Tan, SJ Chen Biophysical journal 90 (4), 1175-1190, 2006 | 443 | 2006 |
| RNA folding: conformational statistics, folding kinetics, and ion electrostatics SJ Chen Annu. Rev. Biophys. 37 (1), 197-214, 2008 | 346 | 2008 |
| RNA-Puzzles: a CASP-like evaluation of RNA three-dimensional structure prediction JA Cruz, MF Blanchet, M Boniecki, JM Bujnicki, SJ Chen, S Cao, R Das, ... Rna 18 (4), 610-625, 2012 | 340 | 2012 |
| RNA folding energy landscapes SJ Chen, KA Dill Proceedings of the National Academy of Sciences 97 (2), 646-651, 2000 | 274 | 2000 |
| RNA-Puzzles Round III: 3D RNA structure prediction of five riboswitches and one ribozyme Z Miao, RW Adamiak, M Antczak, RT Batey, AJ Becka, M Biesiada, ... Rna 23 (5), 655-672, 2017 | 219 | 2017 |
| RNA-Puzzles Round II: assessment of RNA structure prediction programs applied to three large RNA structures Z Miao, RW Adamiak, MF Blanchet, M Boniecki, JM Bujnicki, SJ Chen, ... Rna 21 (6), 1066-1084, 2015 | 217 | 2015 |
| Vfold: a web server for RNA structure and folding thermodynamics prediction X Xu, P Zhao, SJ Chen PloS one 9 (9), e107504, 2014 | 203 | 2014 |
| Physics-based de novo prediction of RNA 3D structures S Cao, SJ Chen The journal of physical chemistry B 115 (14), 4216-4226, 2011 | 198 | 2011 |
| Predicting RNA pseudoknot folding thermodynamics S Cao, SJ Chen Nucleic acids research 34 (9), 2634-2652, 2006 | 197 | 2006 |
| Rational truncation of an RNA aptamer to prostate-specific membrane antigen using computational structural modeling WM Rockey, FJ Hernandez, SY Huang, S Cao, CA Howell, GS Thomas, ... Nucleic acid therapeutics 21 (5), 299-314, 2011 | 173 | 2011 |
| RNA hairpin-folding kinetics W Zhang, SJ Chen Proceedings of the National Academy of Sciences 99 (4), 1931-1936, 2002 | 173 | 2002 |
| Electrostatic correlations and fluctuations for ion binding to a finite length polyelectrolyte ZJ Tan, SJ Chen The Journal of chemical physics 122 (4), 044903, 2005 | 168 | 2005 |
| Cas9-specific immune responses compromise local and systemic AAV CRISPR therapy in multiple dystrophic canine models CH Hakim, SRP Kumar, DO Pérez-López, NB Wasala, D Zhang, Y Yue, ... Nature communications 12 (1), 6769, 2021 | 166 | 2021 |
| RNA-Puzzles Round IV: 3D structure predictions of four ribozymes and two aptamers Z Miao, RW Adamiak, M Antczak, MJ Boniecki, J Bujnicki, SJ Chen, ... Rna 26 (8), 982-995, 2020 | 161 | 2020 |
| Predicting RNA folding thermodynamics with a reduced chain representation model S Cao, SJ Chen Rna 11 (12), 1884-1897, 2005 | 161 | 2005 |
| Salt dependence of nucleic acid hairpin stability ZJ Tan, SJ Chen Biophysical journal 95 (2), 738-752, 2008 | 134 | 2008 |
| Theory and modeling of RNA structure and interactions with metal ions and small molecules LZ Sun, D Zhang, SJ Chen Annual review of biophysics 46 (1), 227-246, 2017 | 128 | 2017 |
| Predicting structures and stabilities for H-type pseudoknots with interhelix loops S Cao, SJ Chen RNA 15 (4), 696-706, 2009 | 121 | 2009 |
| RNA helix stability in mixed Na+/Mg2+ solution ZJ Tan, SJ Chen Biophysical journal 92 (10), 3615-3632, 2007 | 119 | 2007 |
| Salt contribution to RNA tertiary structure folding stability ZJ Tan, SJ Chen Biophysical journal 101 (1), 176-187, 2011 | 117 | 2011 |