| A model of cardiac electrical activity incorporating ionic pumps and concentration changes D Di Francesco, D Noble Philosophical Transactions of the Royal Society of London. B, Biological …, 1985 | 1188 | 1985 |
| Pacemaker mechanisms in cardiac tissue D DiFrancesco Annual review of physiology 55 (1), 455-472, 1993 | 1161 | 1993 |
| Direct activation of cardiac pacemaker channels by intracellular cyclic AMP D DiFrancesco, P Tortora Nature 351 (6322), 145-147, 1991 | 1122 | 1991 |
| How does adrenaline accelerate the heart? HF Brown, D DiFrancesco, SJ Noble Nature 280 (5719), 235-236, 1979 | 922 | 1979 |
| The role of the funny current in pacemaker activity D DiFrancesco Circulation research 106 (3), 434-446, 2010 | 784 | 2010 |
| Heart Rate Lowering by Specific and Selective If Current Inhibition with Ivabradine: A New Therapeutic Perspective in Cardiovascular Disease D DiFrancesco, JA Camm Drugs 64 (16), 1757-1765, 2004 | 659 | 2004 |
| Properties of the hyperpolarizing‐activated current (if) in cells isolated from the rabbit sino‐atrial node. D DiFrancesco, A Ferroni, M Mazzanti, C Tromba The Journal of physiology 377 (1), 61-88, 1986 | 639 | 1986 |
| Familial sinus bradycardia associated with a mutation in the cardiac pacemaker channel R Milanesi, M Baruscotti, T Gnecchi-Ruscone, D DiFrancesco New England Journal of Medicine 354 (2), 151-157, 2006 | 553 | 2006 |
| A new interpretation of the pace‐maker current in calf Purkinje fibres. D DiFrancesco The Journal of physiology 314 (1), 359-376, 1981 | 546 | 1981 |
| Molecular architecture of the human sinus node: insights into the function of the cardiac pacemaker NJ Chandler, ID Greener, JO Tellez, S Inada, H Musa, P Molenaar, ... Circulation 119 (12), 1562-1575, 2009 | 545 | 2009 |
| Physiology and pharmacology of the cardiac pacemaker (“funny”) current M Baruscotti, A Bucchi, D DiFrancesco Pharmacology & therapeutics 107 (1), 59-79, 2005 | 509 | 2005 |
| Voltage‐clamp investigations of membrane currents underlying pace‐maker activity in rabbit sino‐atrial node. H Brown, D DiFrancesco The Journal of physiology 308 (1), 331-351, 1980 | 477 | 1980 |
| A study of the ionic nature of the pace‐maker current in calf Purkinje fibres. D DiFrancesco The Journal of physiology 314 (1), 377-393, 1981 | 469 | 1981 |
| Current-dependent block of rabbit sino-atrial node If channels by ivabradine A Bucchi, M Baruscotti, D DiFrancesco The Journal of general physiology 120 (1), 1, 2002 | 411 | 2002 |
| From funny current to HCN channels: 20 years of excitation EA Accili, C Proenza, M Baruscotti, D DiFrancesco Physiology 17 (1), 32-37, 2002 | 377 | 2002 |
| Characterization of single pacemaker channels in cardiac sino-atrial node cells D DiFrancesco Nature 324 (6096), 470-473, 1986 | 377 | 1986 |
| JMCC Point-Counterpoint: what keeps us ticking, a funny current, a Calcium clock, or both? EG Lakatta, D DiFrancesco Journal of molecular and cellular cardiology 47 (2), 157, 2009 | 376 | 2009 |
| Muscarinic modulation of cardiac rate at low acetylcholine concentrations D DiFrancesco, P Ducouret, RB Robinson Science 243 (4891), 669-671, 1989 | 373 | 1989 |
| Exercise training reduces resting heart rate via downregulation of the funny channel HCN4 A D’Souza, A Bucchi, AB Johnsen, SJRJ Logantha, O Monfredi, J Yanni, ... Nature communications 5 (1), 3775, 2014 | 351 | 2014 |
| Deep bradycardia and heart block caused by inducible cardiac-specific knockout of the pacemaker channel gene Hcn4 M Baruscotti, A Bucchi, C Viscomi, G Mandelli, G Consalez, ... Proceedings of the National Academy of Sciences 108 (4), 1705-1710, 2011 | 350 | 2011 |
Anna MoroniProfessor of Physiology, University of MilanVerified email at unimi.it
