| Circular RNAs are abundant, conserved, and associated with ALU repeats WR Jeck, JA Sorrentino, K Wang, MK Slevin, CE Burd, J Liu, WF Marzluff, ... Rna 19 (2), 141-157, 2013 | 4698 | 2013 |
| Genomic classification of cutaneous melanoma R Akbani, KC Akdemir, BA Aksoy, M Albert, A Ally, SB Amin, H Arachchi, ... Cell 161 (7), 1681-1696, 2015 | 3181 | 2015 |
| Detecting and characterizing circular RNAs WR Jeck, NE Sharpless Nature biotechnology 32 (5), 453-461, 2014 | 2764 | 2014 |
| Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice J Chang, Y Wang, L Shao, RM Laberge, M Demaria, J Campisi, ... Nature medicine 22 (1), 78-83, 2016 | 2040 | 2016 |
| Senescence in health and disease S He, NE Sharpless Cell 169 (6), 1000-1011, 2017 | 1963 | 2017 |
| Ink4a/Arf expression is a biomarker of aging J Krishnamurthy, C Torrice, MR Ramsey, GI Kovalev, K Al-Regaiey, L Su, ... The Journal of clinical investigation 114 (9), 1299-1307, 2004 | 1884 | 2004 |
| Cellular senescence promotes adverse effects of chemotherapy and cancer relapse. Cancer Discov. M Demaria, MN O’leary, J Chang, L Shao, S Liu, F Alimirah, K Koenig, ... CD-16-0241.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 2017 | 1481* | 2017 |
| Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a V Janzen, R Forkert, HE Fleming, Y Saito, MT Waring, DM Dombkowski, ... Nature 443 (7110), 421-426, 2006 | 1339 | 2006 |
| The regulation of INK4/ARF in cancer and aging WY Kim, NE Sharpless Cell 127 (2), 265-275, 2006 | 1313 | 2006 |
| Forging a signature of in vivo senescence NE Sharpless, CJ Sherr Nature Reviews Cancer 15 (7), 397-408, 2015 | 1301 | 2015 |
| LKB1 modulates lung cancer differentiation and metastasis H Ji, MR Ramsey, DN Hayes, C Fan, K McNamara, P Kozlowski, C Torrice, ... Nature 448 (7155), 807-810, 2007 | 1275 | 2007 |
| Increasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageing AV Molofsky, SG Slutsky, NM Joseph, S He, R Pardal, J Krishnamurthy, ... Nature 443 (7110), 448-452, 2006 | 1207 | 2006 |
| p16INK4a induces an age-dependent decline in islet regenerative potential J Krishnamurthy, MR Ramsey, KL Ligon, C Torrice, A Koh, S Bonner-Weir, ... Nature 443 (7110), 453-457, 2006 | 1164 | 2006 |
| How stem cells age and why this makes us grow old NE Sharpless, RA DePinho Nature reviews Molecular cell biology 8 (9), 703-713, 2007 | 1142 | 2007 |
| Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk CE Burd, WR Jeck, Y Liu, HK Sanoff, Z Wang, NE Sharpless PLoS genetics 6 (12), e1001233, 2010 | 1059 | 2010 |
| Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis NE Sharpless, N Bardeesy, KH Lee, D Carrasco, DH Castrillon, ... Nature 413 (6851), 86-91, 2001 | 1033 | 2001 |
| Dynamic reprogramming of the kinome in response to targeted MEK inhibition in triple-negative breast cancer JS Duncan, MC Whittle, K Nakamura, AN Abell, AA Midland, ... Cell 149 (2), 307-321, 2012 | 908 | 2012 |
| Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis RM Bachoo, EA Maher, KL Ligon, NE Sharpless, SS Chan, MJ You, ... Cancer cell 1 (3), 269-277, 2002 | 872 | 2002 |
| The mighty mouse: genetically engineered mouse models in cancer drug development NE Sharpless, RA DePinho Nature reviews Drug discovery 5 (9), 741-754, 2006 | 826 | 2006 |
| CDK4/6 inhibition augments antitumor immunity by enhancing T-cell activation J Deng, ES Wang, RW Jenkins, S Li, R Dries, K Yates, S Chhabra, ... Cancer discovery 8 (2), 216-233, 2018 | 788 | 2018 |
Ronald A. DePinhoMD AndersonVerified email at mdanderson.org
