| The pseudokinase MLKL mediates necroptosis via a molecular switch mechanism JM Murphy, PE Czabotar, JM Hildebrand, IS Lucet, JG Zhang, ... Immunity 39 (3), 443-453, 2013 | 1392 | 2013 |
| RIPK1 regulates RIPK3-MLKL-driven systemic inflammation and emergency hematopoiesis JA Rickard, JA O’Donnell, JM Evans, N Lalaoui, AR Poh, TW Rogers, ... Cell 157 (5), 1175-1188, 2014 | 668 | 2014 |
| Differential inhibition of TRAIL-mediated DR5-DISC formation by decoy receptors 1 and 2 D Mérino, N Lalaoui, A Morizot, P Schneider, E Solary, O Micheau Molecular and cellular biology 26 (19), 7046-7055, 2006 | 429 | 2006 |
| Tumor immune evasion arises through loss of TNF sensitivity CJ Kearney, SJ Vervoort, SJ Hogg, KM Ramsbottom, AJ Freeman, ... Science immunology 3 (23), eaar3451, 2018 | 398 | 2018 |
| MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, ... Nature communications 11 (1), 3151, 2020 | 346 | 2020 |
| Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease N Lalaoui, SE Boyden, H Oda, GM Wood, DL Stone, D Chau, L Liu, ... Nature 577 (7788), 103-108, 2020 | 328 | 2020 |
| MK2 phosphorylates RIPK1 to prevent TNF-induced cell death I Jaco, A Annibaldi, N Lalaoui, R Wilson, T Tenev, L Laurien, C Kim, ... Molecular cell 66 (5), 698-710. e5, 2017 | 328 | 2017 |
| TNFR1-dependent cell death drives inflammation in Sharpin-deficient mice JA Rickard, H Anderton, N Etemadi, U Nachbur, M Darding, N Peltzer, ... Elife 3, e03464, 2014 | 287 | 2014 |
| The pseudokinase MLKL and the kinase RIPK3 have distinct roles in autoimmune disease caused by loss of death-receptor-induced apoptosis S Alvarez-Diaz, CP Dillon, N Lalaoui, MC Tanzer, DA Rodriguez, A Lin, ... Immunity 45 (3), 513-526, 2016 | 250 | 2016 |
| The molecular relationships between apoptosis, autophagy and necroptosis N Lalaoui, LM Lindqvist, JJ Sandow, PG Ekert Seminars in cell & developmental biology 39, 63-69, 2015 | 234 | 2015 |
| Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer D Merino, JR Whittle, F Vaillant, A Serrano, JN Gong, G Giner, ... Science translational medicine 9 (401), eaam7049, 2017 | 215 | 2017 |
| TRAIL in cancer therapy: present and future challenges D Mérino, N Lalaoui, A Morizot, E Solary, O Micheau Expert opinion on therapeutic targets 11 (10), 1299-1314, 2007 | 209 | 2007 |
| dsRNA induces apoptosis through an atypical death complex associating TLR3 to caspase-8 Y Estornes, F Toscano, F Virard, G Jacquemin, A Pierrot, B Vanbervliet, ... Cell Death & Differentiation 19 (9), 1482-1494, 2012 | 205 | 2012 |
| The caspase-8 inhibitor emricasan combines with the SMAC mimetic birinapant to induce necroptosis and treat acute myeloid leukemia G Brumatti, C Ma, N Lalaoui, NY Nguyen, M Navarro, MC Tanzer, ... Science translational medicine 8 (339), 339ra69-339ra69, 2016 | 197 | 2016 |
| cIAPs and XIAP regulate myelopoiesis through cytokine production in an RIPK1-and RIPK3-dependent manner WWL Wong, JE Vince, N Lalaoui, KE Lawlor, D Chau, A Bankovacki, ... Blood, The Journal of the American Society of Hematology 123 (16), 2562-2572, 2014 | 184 | 2014 |
| The TNF receptor superfamily-NF-κB axis is critical to maintain effector regulatory T cells in lymphoid and non-lymphoid tissues A Vasanthakumar, Y Liao, P Teh, MF Pascutti, AE Oja, AL Garnham, ... Cell reports 20 (12), 2906-2920, 2017 | 159 | 2017 |
| Targeting p38 or MK2 enhances the anti-leukemic activity of Smac-mimetics N Lalaoui, K Hänggi, G Brumatti, D Chau, NYN Nguyen, L Vasilikos, ... Cancer cell 29 (2), 145-158, 2016 | 126 | 2016 |
| Dynamics of HPV16 DNA load reflect the natural history of cervical HPV-associated lesions S Monnier-Benoit, V Dalstein, D Riethmuller, N Lalaoui, C Mougin, ... Journal of clinical virology 35 (3), 270-277, 2006 | 117 | 2006 |
| Viral MLKL homologs subvert necroptotic cell death by sequestering cellular RIPK3 EJ Petrie, JJ Sandow, WIL Lehmann, LY Liang, D Coursier, SN Young, ... Cell reports 28 (13), 3309-3319. e5, 2019 | 115 | 2019 |
| TRAIL-R4 promotes tumor growth and resistance to apoptosis in cervical carcinoma HeLa cells through AKT N Lalaoui, A Morlé, D Merino, G Jacquemin, E Iessi, A Morizot, S Shirley, ... PloS one 6 (5), e19679, 2011 | 109 | 2011 |
John SilkeProfessor, The Walter and Eliza Hall InstituteVerified email at latrobe.edu.au
