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Scott Widenmaier
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Coordinated regulation of protein synthesis and degradation by mTORC1
Y Zhang, J Nicholatos, JR Dreier, SJH Ricoult, SB Widenmaier, ...
Nature 513 (7518), 440-443, 2014
4192014
NRF1 is an ER membrane sensor that is central to cholesterol homeostasis
SB Widenmaier, NA Snyder, TB Nguyen, A Arduini, GY Lee, AP Arruda, ...
Cell 171 (5), 1094-1109. e15, 2017
2652017
Glucose‐dependent insulinotropic polypeptide (gastric inhibitory polypeptide; GIP)
CHS McIntosh, S Widenmaier, SJ Kim
Vitamins & Hormones 80, 409-471, 2009
2502009
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
A Bartelt, SB Widenmaier, C Schlein, K Johann, RLS Goncalves, K Eguchi, ...
Nature medicine 24 (3), 292-303, 2018
2282018
Glucose-Dependent Insulinotropic Polypeptide-Mediated Up-Regulation of β-Cell Antiapoptotic Bcl-2 Gene Expression Is Coordinated by Cyclic AMP (cAMP …
SJ Kim, C Nian, S Widenmaier, CHS McIntosh
Molecular and cellular biology 28 (5), 1644-1656, 2008
1682008
A GIP receptor agonist exhibits β-cell anti-apoptotic actions in rat models of diabetes resulting in improved β-cell function and glycemic control
SB Widenmaier, SJ Kim, GK Yang, T De Los Reyes, C Nian, A Asadi, ...
PloS one 5 (3), e9590, 2010
1292010
Suppression of p38 MAPK and JNK via Akt-mediated inhibition of apoptosis signal-regulating kinase 1 constitutes a core component of the β-cell pro-survival effects of glucose …
SB Widenmaier, Z Ao, SJ Kim, G Warnock, CHS McIntosh
Journal of Biological Chemistry 284 (44), 30372-30382, 2009
1192009
Bcl-2 and Bcl-xL suppress glucose signaling in pancreatic β-cells
DS Luciani, SA White, SB Widenmaier, VV Saran, F Taghizadeh, X Hu, ...
Diabetes 62 (1), 170-182, 2013
1022013
Glucose‐dependent insulinotropic polypeptide signaling in pancreatic β‐cells and adipocytes
CHS McIntosh, S Widenmaier, SJ Kim
Journal of diabetes investigation 3 (2), 96-106, 2012
682012
Pleiotropic actions of the incretin hormones
CHS McIntosh, S Widenmaier, SJ Kim
Vitamins & Hormones 84, 21-79, 2010
502010
Pancreatic β-cell prosurvival effects of the incretin hormones involve post-translational modification of Kv2. 1 delayed rectifier channels
SJ Kim, SB Widenmaier, WS Choi, C Nian, Z Ao, G Warnock, ...
Cell Death & Differentiation 19 (2), 333-344, 2012
472012
Noncanonical activation of Akt/protein kinase B in β-cells by the incretin hormone glucose-dependent insulinotropic polypeptide
SB Widenmaier, AV Sampaio, TM Underhill, CHS McIntosh
Journal of Biological Chemistry 284 (16), 10764-10773, 2009
452009
Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
MG Akl, L Li, R Baccetto, S Phanse, Q Zhang, MJ Trites, S McDonald, ...
Cell reports 42 (4), 2023
372023
Proteostasis in thermogenesis and obesity
A Bartelt, SB Widenmaier
Biological Chemistry 401 (9), 1019-1030, 2020
332020
Only iron-limited cells of the cyanobacterium Anabaena flos-aquae inhibit growth of the green alga Chlamydomonas reinhardtii
CJ Matz, MR Christensen, AD Bone, CD Gress, SB Widenmaier, ...
Canadian journal of botany 82 (4), 436-442, 2004
242004
Sterol O-acyltransferase (SOAT/ACAT) activity is required to form cholesterol crystals in hepatocyte lipid droplets
JA Bairos, U Njoku, M Zafar, MG Akl, L Li, G Parlakgul, AP Arruda, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2024
132024
Protective effects of hepatocyte stress defenders, Nrf1 and Nrf2, against MASLD progression
MG Akl, L Li, SB Widenmaier
International journal of molecular sciences 25 (15), 8046, 2024
122024
HDL functionality is dependent on hepatocyte stress defense factors Nrf1 and Nrf2
MJ Trites, BM Stebbings, H Aoki, S Phanse, MG Akl, L Li, M Babu, ...
Frontiers in physiology 14, 1212785, 2023
92023
Nesfatin-1 and nesfatin-1-like peptide attenuate hepatocyte lipid accumulation and nucleobindin-1 disruption modulates lipid metabolic pathways
A Nasri, M Kowaluk, SB Widenmaier, S Unniappan
Communications Biology 7 (1), 623, 2024
72024
Euglycemia is affected by stress defense factor hepatocyte NRF1, but not NRF2
MG Akl, R Baccetto, BM Stebbings, L Li, SB Widenmaier
Biochemical and Biophysical Research Communications 668, 96-103, 2023
72023
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