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Julien Couture-Senécal
Julien Couture-Senécal
Verified email at mit.edu - Homepage
Title
Cited by
Cited by
Year
The dose threshold for nanoparticle tumour delivery
B Ouyang, W Poon, YN Zhang, ZP Lin, BR Kingston, AJ Tavares, Y Zhang, ...
Nature materials 19 (12), 1362-1371, 2020
5212020
Iterative design of ionizable lipids for intramuscular mRNA delivery
G Tilstra, J Couture-Senécal, YMA Lau, AM Manning, DSM Wong, ...
Journal of the American Chemical Society 145 (4), 2294-2304, 2023
1132023
Impact of tumor barriers on nanoparticle delivery to macrophages
B Ouyang, BR Kingston, W Poon, YN Zhang, ZP Lin, AM Syed, ...
Molecular Pharmaceutics 19 (6), 1917-1925, 2022
142022
A cell-free kinetic analysis of ionizable lipid hydrolysis
J Couture-Senécal, J Natraj, OF Khan
Analytical Chemistry 96 (43), 17128-17134, 2024
122024
The engineering challenges and opportunities when designing potent ionizable materials for the delivery of ribonucleic acids
YMA Lau, J Pang, G Tilstra, J Couture-Senécal, OF Khan
Expert Opinion on Drug Delivery 19 (12), 1650-1663, 2022
112022
Ionizable Lipid with Supramolecular Chemistry Features for RNA Delivery In Vivo
AM Manning, G Tilstra, AB Khan, J Couture‐Senécal, YMA Lau, J Pang, ...
Small 19 (41), 2302917, 2023
102023
Engineering ionizable lipids for rapid biodegradation balances mRNA vaccine efficacy and tolerability
J Couture-Senécal, G Tilstra, OF Khan
BioRxiv, 2024.08. 02.606386, 2024
82024
mRNA vaccines: Immunology and present and future potential
OF Khan, J Couture-Senécal, YMA Lau, AM Oproescu, J Pang, G Tilstra, ...
The COVID-19 Pandemic: Science, Technology, and the Future of Healthcare …, 2024
22024
The Clearance of Human Cytomegalovirus Using CRISPR/Cas9 RNA Lipid Nanoparticles
YMA Lau, J Pang, MQ Jiang, Y Sun, KLM Knaggs, G Tilstra, AM Oproescu, ...
bioRxiv, 2025.12. 17.694960, 2025
2025
Rapid Chemical Synthesis of Neuroprotective Hi1a
SA Byrne, G Fittolani, E Shimshoni, CE Farquhar, J Couture-Senécal, ...
The Journal of Organic Chemistry, 2025
2025
Supramolecular ionizable lipid molecules with heteroatomic tuning for nucleic acid delivery
J Couture-Senécal, G Tilstra, OF Khan
US Patent App. 18/621,526, 2025
2025
Rational design of ionizable lipids for intramuscular messenger ribonucleic acid vaccines
J Couture-Senécal
University of Toronto (Canada), 2025
2025
Multi-motif dendrons and their supramolecular structures and uses thereof
OF Khan, G Tilstra, AM Manning, YMA Lau, J Couture-Senécal
US Patent App. 18/622,324, 2024
2024
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Articles 1–13