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Alexis Courbet
Alexis Courbet
Translational Investigator, Institute for Protein Design, University of Washington
Verified email at uw.edu
Title
Cited by
Cited by
Year
De novo design of protein structure and function with RFdiffusion
JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ...
Nature 620 (7976), 1089-1100, 2023
21962023
Robust deep learning–based protein sequence design using ProteinMPNN
J Dauparas, I Anishchenko, N Bennett, H Bai, RJ Ragotte, LF Milles, ...
Science 378 (6615), 49-56, 2022
20062022
Detection of pathological biomarkers in human clinical samples via amplifying genetic switches and logic gates
A Courbet, D Endy, E Renard, F Molina, J Bonnet
Science translational medicine 7 (289), 289ra83-289ra83, 2015
3252015
Hallucinating symmetric protein assemblies
BIM Wicky, LF Milles, A Courbet, RJ Ragotte, J Dauparas, E Kinfu, S Tipps, ...
Science 378 (6615), 56-61, 2022
2542022
Broadly applicable and accurate protein design by integrating structure prediction networks and diffusion generative models
JL Watson, D Juergens, NR Bennett, BL Trippe, J Yim, HE Eisenach, ...
BioRxiv, 2022.12. 09.519842, 2022
2532022
Top-down design of protein architectures with reinforcement learning
ID Lutz, S Wang, C Norn, A Courbet, AJ Borst, YT Zhao, A Dosey, L Cao, ...
Science 380 (6642), 266-273, 2023
1422023
Design of multi-scale protein complexes by hierarchical building block fusion
Y Hsia, R Mout, W Sheffler, NI Edman, I Vulovic, YJ Park, RL Redler, ...
Nature Communications 12 (1), 2294, 2021
932021
Reconfigurable asymmetric protein assemblies through implicit negative design
DD Sahtoe, F Praetorius, A Courbet, Y Hsia, BIM Wicky, NI Edman, ...
Science 375 (6578), eabj7662, 2022
812022
Computational design of mechanically coupled axle-rotor protein assemblies
A Courbet, J Hansen, Y Hsia, N Bethel, YJ Park, C Xu, A Moyer, ...
Science 376 (6591), 383-390, 2022
682022
Blueprinting extendable nanomaterials with standardized protein blocks
TF Huddy, Y Hsia, RD Kibler, J Xu, N Bethel, D Nagarajan, R Redler, ...
Nature 627 (8005), 898-904, 2024
602024
Accurate computational design of three-dimensional protein crystals
Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MY Yaman, MJ Bick, ...
Nature Materials 22 (12), 1556-1563, 2023
552023
Generation of ordered protein assemblies using rigid three-body fusion
I Vulovic, Q Yao, YJ Park, A Courbet, A Norris, F Busch, A Sahasrabuddhe, ...
Proceedings of the National Academy of Sciences 118 (23), e2015037118, 2021
482021
Bringing next‐generation diagnostics to the clinic through synthetic biology
A Courbet, E Renard, F Molina
EMBO molecular medicine 8 (9), 987-991, 2016
372016
Computer‐aided biochemical programming of synthetic microreactors as diagnostic devices
A Courbet, P Amar, F Fages, E Renard, F Molina
Molecular Systems Biology 14 (4), e7845, 2018
362018
Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity
A Courbet, N Bec, C Constant, C Larroque, M Pugniere, S El Messaoudi, ...
PLoS One 12 (8), e0182022, 2017
292017
Hallucination of closed repeat proteins containing central pockets
L An, DR Hicks, D Zorine, J Dauparas, BIM Wicky, LF Milles, A Courbet, ...
Nature Structural & Molecular Biology 30 (11), 1755-1760, 2023
152023
Self-assembly–based posttranslational protein oscillators
O Kimchi, CP Goodrich, A Courbet, AI Curatolo, NB Woodall, D Baker, ...
Science Advances 6 (51), eabc1939, 2020
152020
Computing with synthetic protocells
A Courbet, F Molina, P Amar
Acta biotheoretica 63 (3), 309-323, 2015
92015
Protein identification using cryo-EM and artificial intelligence guides improved sample purification
KD Carr, DED Zambrano, C Weidle, A Goodson, HE Eisenach, H Pyles, ...
Journal of Structural Biology: X 11, 100120, 2025
82025
Accurate computational design of 3D protein crystals
Z Li, S Wang, U Nattermann, AK Bera, AJ Borst, MJ Bick, EC Yang, ...
bioRxiv, 2022.11. 18.517014, 2022
82022
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Articles 1–20