| Drug delivery systems: entering the mainstream TM Allen, PR Cullis Science 303 (5665), 1818-1822, 2004 | 6092 | 2004 |
| Liposomal drug delivery systems: from concept to clinical applications TM Allen, PR Cullis Advanced drug delivery reviews 65 (1), 36-48, 2013 | 5940 | 2013 |
| Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential MJ Hope, MB Bally, G Webb, PR Cullis Biochimica et Biophysica Acta (BBA)-Biomembranes 812 (1), 55-65, 1985 | 2750 | 1985 |
| Vesicles of variable sizes produced by a rapid extrusion procedure LD Mayer, MJ Hope, PR Cullis Biochimica et Biophysica Acta (BBA)-Biomembranes 858 (1), 161-168, 1986 | 2278 | 1986 |
| Rational design of cationic lipids for siRNA delivery SC Semple, A Akinc, J Chen, AP Sandhu, BL Mui, CK Cho, DWY Sah, ... Nature biotechnology 28 (2), 172-176, 2010 | 2248 | 2010 |
| The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs A Akinc, MA Maier, M Manoharan, K Fitzgerald, M Jayaraman, S Barros, ... Nature nanotechnology 14 (12), 1084-1087, 2019 | 1685 | 2019 |
| Maximizing the potency of siRNA lipid nanoparticles for hepatic gene silencing in vivo M Jayaraman, SM Ansell, BL Mui, YK Tam, J Chen, X Du, D Butler, ... Angewandte Chemie International Edition 51 (34), 8529-8533, 2012 | 1524 | 2012 |
| The current landscape of nucleic acid therapeutics JA Kulkarni, D Witzigmann, SB Thomson, S Chen, BR Leavitt, PR Cullis, ... Nature nanotechnology 16 (6), 630-643, 2021 | 1385 | 2021 |
| Lipid nanoparticle systems for enabling gene therapies PR Cullis, MJ Hope Molecular Therapy 25 (7), 1467-1475, 2017 | 1230 | 2017 |
| Microfluidic synthesis of highly potent limit-size lipid nanoparticles for in vivo delivery of siRNA NM Belliveau, J Huft, PJC Lin, S Chen, AKK Leung, TJ Leaver, AW Wild, ... Molecular therapy Nucleic acids 1, 2012 | 927 | 2012 |
| Liposomal compositions for enhanced retention of bioactive agents MB Bally, NL Boman, PR Cullis, LD Mayer US Patent 5,595,756, 1997 | 868 | 1997 |
| On the mechanism whereby cationic lipids promote intracellular delivery of polynucleic acids IM Hafez, N Maurer, PR Cullis Gene therapy 8 (15), 1188-1196, 2001 | 781 | 2001 |
| Biodegradable lipids enabling rapidly eliminated lipid nanoparticles for systemic delivery of RNAi therapeutics MA Maier, M Jayaraman, S Matsuda, J Liu, S Barros, W Querbes, YK Tam, ... Molecular Therapy 21 (8), 1570-1578, 2013 | 688 | 2013 |
| On the formation and morphology of lipid nanoparticles containing ionizable cationic lipids and siRNA JA Kulkarni, MM Darjuan, JE Mercer, S Chen, R Van Der Meel, ... ACS nano 12 (5), 4787-4795, 2018 | 675 | 2018 |
| Efficient encapsulation of antisense oligonucleotides in lipid vesicles using ionizable aminolipids: formation of novel small multilamellar vesicle structures SC Semple, SK Klimuk, TO Harasym, N Dos Santos, SM Ansell, KF Wong, ... Biochimica et Biophysica Acta (BBA)-Biomembranes 1510 (1-2), 152-166, 2001 | 666 | 2001 |
| Nomenclature for synthetic gene delivery systems PL Felgner, Y Barenholz, JP Behr, SH Cheng, P Cullis, L Huang, ... Human gene therapy 8 (5), 511-512, 1997 | 657 | 1997 |
| Association of blood proteins with large unilamellar liposomes in vivo. Relation to circulation lifetimes. A Chonn, SC Semple, PR Cullis Journal of Biological Chemistry 267 (26), 18759-18765, 1992 | 625 | 1992 |
| Lipid nanoparticles enabling gene therapies: from concepts to clinical utility JA Kulkarni, PR Cullis, R Van Der Meel Nucleic acid therapeutics 28 (3), 146-157, 2018 | 609 | 2018 |
| Solute distributions and trapping efficiencies observed in freeze-thawed multilamellar vesicles LD Mayer, MJ Hope, PR Cullis, AS Janoff Biochimica et Biophysica Acta (BBA)-Biomembranes 817 (1), 193-196, 1985 | 609 | 1985 |
| The liposomal formulation of doxorubicin SA Abraham, DN Waterhouse, LD Mayer, PR Cullis, TD Madden, ... Methods in enzymology 391, 71-97, 2005 | 598 | 2005 |
Bally MBC CancerVerified email at bccrc.ca
