| ES cells do not activate p53-dependent stress responses and undergo p53-independent apoptosis in response to DNA damage MI Aladjem, BT Spike, LW Rodewald, TJ Hope, M Klemm, R Jaenisch, ... Current Biology 8 (3), 145-155, 1998 | 559 | 1998 |
| MYC drives temporal evolution of small cell lung cancer subtypes by reprogramming neuroendocrine fate AS Ireland, AM Micinski, DW Kastner, B Guo, SJ Wait, KB Spainhower, ... Cancer cell 38 (1), 60-78. e12, 2020 | 492 | 2020 |
| BNIP3 Is an RB/E2F Target Gene Required for Hypoxia-Induced Autophagy K Tracy, BC Dibling, BT Spike, JR Knabb, P Schumacker, KF Macleod Molecular and cellular biology 27 (17), 6229-6242, 2007 | 483 | 2007 |
| A mammary stem cell population identified and characterized in late embryogenesis reveals similarities to human breast cancer BT Spike, DD Engle, JC Lin, SK Cheung, J La, GM Wahl Cell stem cell 10 (2), 183-197, 2012 | 292 | 2012 |
| Transcriptomic classification of genetically engineered mouse models of breast cancer identifies human subtype counterparts AD Pfefferle, JI Herschkowitz, J Usary, JC Harrell, BT Spike, JR Adams, ... Genome biology 14 (11), R125, 2013 | 273 | 2013 |
| Oligoclonal IgA response in the vascular wall in acute Kawasaki disease AH Rowley, ST Shulman, BT Spike, CA Mask, SC Baker The Journal of Immunology 166 (2), 1334-1343, 2001 | 268 | 2001 |
| Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures H Mizuno, BT Spike, GM Wahl, AJ Levine Proceedings of the National Academy of Sciences 107 (52), 22745-22750, 2010 | 201 | 2010 |
| p53, stem cells, and reprogramming: tumor suppression beyond guarding the genome BT Spike, GM Wahl Genes & cancer 2 (4), 404-419, 2011 | 181 | 2011 |
| Unrestrained erythroblast development in Nix−/− mice reveals a mechanism for apoptotic modulation of erythropoiesis A Diwan, AG Koesters, AM Odley, S Pushkaran, CP Baines, BT Spike, ... Proceedings of the National Academy of Sciences 104 (16), 6794-6799, 2007 | 177 | 2007 |
| Single-cell transcriptomes distinguish stem cell state changes and lineage specification programs in early mammary gland development RR Giraddi, CY Chung, RE Heinz, O Balcioglu, M Novotny, CL Trejo, ... Cell reports 24 (6), 1653-1666. e7, 2018 | 174 | 2018 |
| Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity GM Wahl, BT Spike NPJ breast cancer 3 (1), 14, 2017 | 164 | 2017 |
| New roles for the RB tumor suppressor protein H Liu, B Dibling, B Spike, A Dirlam, K Macleod Current opinion in genetics & development 14 (1), 55-64, 2004 | 147 | 2004 |
| Sox10 regulates stem/progenitor and mesenchymal cell states in mammary epithelial cells C Dravis, BT Spike, JC Harrell, C Johns, CL Trejo, EM Southard-Smith, ... Cell reports 12 (12), 2035-2048, 2015 | 141 | 2015 |
| The multifaceted role of the embryonic gene Cripto-1 in cancer, stem cells and epithelial-mesenchymal transition M Klauzinska, NP Castro, MC Rangel, BT Spike, PC Gray, D Bertolette, ... Seminars in cancer biology 29, 51-58, 2014 | 139 | 2014 |
| The Rb tumor suppressor is required for stress erythropoiesis BT Spike, A Dirlam, BC Dibling, J Marvin, BO Williams, T Jacks, ... The EMBO journal 23 (21), 4319-4329, 2004 | 115 | 2004 |
| Macrophage HIF-1α is an independent prognostic indicator in kidney cancer SJ Cowman, DG Fuja, XD Liu, RSS Tidwell, N Kandula, D Sirohi, ... Clinical Cancer Research 26 (18), 4970-4982, 2020 | 79 | 2020 |
| CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo BT Spike, JA Kelber, E Booker, M Kalathur, R Rodewald, J Lipianskaya, ... Stem cell reports 2 (4), 427-439, 2014 | 77 | 2014 |
| Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts A Dirlam, BT Spike, KF Macleod Molecular and cellular biology 27 (24), 8713-8728, 2007 | 59 | 2007 |
| Stem cells and the developing mammary gland M Makarem, BT Spike, C Dravis, N Kannan, GM Wahl, CJ Eaves Journal of mammary gland biology and neoplasia 18 (2), 209-219, 2013 | 54 | 2013 |
| FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma G Orstad, G Fort, TJ Parnell, A Jones, C Stubben, B Lohman, KL Gillis, ... Developmental cell 57 (15), 1866-1882. e10, 2022 | 47 | 2022 |
