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Jamil Saad, Ph.D
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Structural basis for targeting HIV-1 Gag proteins to the plasma membrane for virus assembly
JS Saad, J Miller, J Tai, A Kim, RH Ghanam, MF Summers
Proceedings of the National Academy of Sciences 103 (30), 11364-11369, 2006
7472006
A New Pneumococcal Capsule Type, 10D, is the 100th Serotype and Has a Large cps Fragment from an Oral Streptococcus
F Ganaie, JS Saad, L McGee, AJ van Tonder, SD Bentley, SW Lo, ...
MBio 11 (3), 10.1128/mbio. 00937-20, 2020
3842020
Point mutations in the HIV-1 matrix protein turn off the myristyl switch
JS Saad, E Loeliger, P Luncsford, M Liriano, J Tai, A Kim, J Miller, A Joshi, ...
Journal of molecular biology 366 (2), 574-585, 2007
1552007
Relationship of solution and protein-bound structures of DNA duplexes with the major intrastrand cross-link lesions formed on cisplatin binding to DNA
LG Marzilli, JS Saad, Z Kuklenyik, KA Keating, Y Xu
Journal of the American Chemical Society 123 (12), 2764-2770, 2001
1332001
The KN-93 molecule inhibits calcium/calmodulin-dependent protein kinase II (CaMKII) activity by binding to Ca2+/CaM
MH Wong, AB Samal, M Lee, J Vlach, N Novikov, A Niedziela-Majka, ...
Journal of molecular biology 431 (7), 1440-1459, 2019
1292019
Discovery of novel pneumococcal serotype 35D, a natural WciG-deficient variant of serotype 35B
KA Geno, JS Saad, MH Nahm
Journal of clinical microbiology 55 (5), 1416-1425, 2017
1022017
Targeting of Murine Leukemia Virus Gag to the Plasma Membrane Is Mediated by PI(4,5)P2/PS and a Polybasic Region in the Matrix
E Hamard-Peron, F Juillard, JS Saad, C Roy, P Roingeard, MF Summers, ...
Journal of virology 84 (1), 503-515, 2010
1022010
Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4, 5)-bisphosphate in membrane targeting
JS Saad, SD Ablan, RH Ghanam, A Kim, K Andrews, K Nagashima, ...
Journal of molecular biology 382 (2), 434-447, 2008
992008
Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers
J Vlach, JS Saad
Proceedings of the National Academy of Sciences 110 (9), 3525-3530, 2013
982013
Discovery of Streptococcus pneumoniae serotype 6 variants with glycosyltransferases synthesizing two differing repeating units
MB Oliver, MPG van der Linden, SA Küntzel, JS Saad, MH Nahm
Journal of Biological Chemistry 288 (36), 25976-25985, 2013
962013
Role of the HIV-1 matrix protein in Gag intracellular trafficking and targeting to the plasma membrane for virus assembly
RH Ghanam, AB Samal, TF Fernandez, JS Saad
Frontiers in microbiology 3, 55, 2012
882012
Solution structure and membrane interaction of the cytoplasmic tail of HIV-1 gp41 protein
RE Murphy, AB Samal, J Vlach, JS Saad
Structure 25 (11), 1708-1718. e5, 2017
672017
Reverse micelle encapsulation of membrane-anchored proteins for solution NMR studies
KG Valentine, RW Peterson, JS Saad, MF Summers, X Xu, JB Ames, ...
Structure 18 (1), 9-16, 2010
652010
A new pneumococcal capsule type, 10D, is the 100th serotype and has a large cps fragment from an oral Streptococcus. mBio 11: e00937-20
F Ganaie, JS Saad, L McGee, AJ van Tonder, SD Bentley, SW Lo, ...
602020
Myristate exposure in the human immunodeficiency virus type 1 matrix protein is modulated by pH
EL Fledderman, K Fujii, RH Ghanam, K Waki, PE Prevelige, EO Freed, ...
Biochemistry 49 (44), 9551-9562, 2010
572010
Structural characterization of Streptococcus pneumoniae serotype 9A capsule polysaccharide reveals role of glycosyl 6-O-acetyltransferase wcjE in serotype 9V capsule …
JJ Calix, JS Saad, AM Brady, MH Nahm
Journal of Biological Chemistry 287 (17), 13996-14003, 2012
522012
Binding of calmodulin to the HIV-1 matrix protein triggers myristate exposure
RH Ghanam, TF Fernandez, EL Fledderman, JS Saad
Journal of Biological Chemistry 285 (53), 41911-41920, 2010
472010
Capsule promotes intracellular survival and vascular endothelial cell translocation during invasive pneumococcal disease
T Brissac, E Martínez, KL Kruckow, AN Riegler, F Ganaie, H Im, S Bakshi, ...
MBio 12 (5), 10.1128/mbio. 02516-21, 2021
462021
The interplay between HIV-1 Gag binding to the plasma membrane and Env incorporation
RE Murphy, JS Saad
Viruses 12 (5), 548, 2020
442020
The tuberculosis necrotizing toxin is an NAD+ and NADP+ glycohydrolase with distinct enzymatic properties
U Tak, J Vlach, A Garza-Garcia, D William, O Danilchanka, ...
Journal of Biological Chemistry 294 (9), 3024-3036, 2019
422019
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Articles 1–20