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Dharmaraja Allimuthu
Dharmaraja Allimuthu
Assistant Professor, IIT Kanpur
Verified email at iitk.ac.in - Homepage
Title
Cited by
Cited by
Year
Role of reactive oxygen species (ROS) in therapeutics and drug resistance in cancer and bacteria
AT Dharmaraja
Journal of medicinal chemistry 60 (8), 3221-3240, 2017
6282017
Accumulation of 8, 9-unsaturated sterols drives oligodendrocyte formation and remyelination
Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, ...
Nature 560 (7718), 372-376, 2018
2412018
Mycobacterium tuberculosis has diminished capacity to counteract redox stress induced by elevated levels of endogenous superoxide
P Tyagi, AT Dharmaraja, A Bhaskar, H Chakrapani, A Singh
Free Radical Biology and Medicine 84, 344-354, 2015
1062015
Facile synthesis of nitroamino-1, 3, 4-oxadiazole with azo linkage: a new family of high-performance and biosafe energetic materials
S Banik, P Kumar, VD Ghule, S Khanna, D Allimuthu, S Dharavath
Journal of Materials Chemistry A 10 (42), 22803-22811, 2022
592022
2-Chloropropionamide as a low-reactivity electrophile for irreversible small-molecule probe identification
D Allimuthu, DJ Adams
ACS chemical biology 12 (8), 2124-2131, 2017
462017
Design, synthesis and evaluation of small molecule reactive oxygen species generators as selective Mycobacterium tuberculosis inhibitors
AT Dharmaraja, M Alvala, D Sriram, P Yogeeswari, H Chakrapani
Chemical communications 48 (83), 10325-10327, 2012
452012
Diverse chemical scaffolds enhance oligodendrocyte formation by inhibiting CYP51, TM7SF2, or EBP
D Allimuthu, Z Hubler, FJ Najm, H Tang, I Bederman, W Seibel, PJ Tesar, ...
Cell Chemical Biology 26 (4), 593-599. e4, 2019
422019
A small molecule for controlled generation of reactive oxygen species (ROS)
AT Dharmaraja, H Chakrapani
Organic letters 16 (2), 398-401, 2014
422014
Arylboronate ester based diazeniumdiolates (BORO/NO), a class of hydrogen peroxide inducible nitric oxide (NO) donors
AT Dharmaraja, G Ravikumar, H Chakrapani
Organic letters 16 (10), 2610-2613, 2014
412014
Mercury (II)–methylene blue interactions: Complexation and metallate formation
MM Raj, A Dharmaraja, SJ Kavitha, K Panchanatheswaran, DE Lynch
Inorganica chimica acta 360 (6), 1799-1808, 2007
382007
Extraction of fission palladium (II) from nitric acid by benzoylmethylenetriphenylphosphorane (BMTPP)
MM Raj, A Dharmaraja, K Panchanatheswaran, KA Venkatesan, ...
Hydrometallurgy 84 (1-2), 118-124, 2006
352006
Modulation of lanosterol synthase drives 24, 25-epoxysterol synthesis and oligodendrocyte formation
Z Hubler, RM Friedrich, JL Sax, D Allimuthu, F Gao, AM Rivera-León, ...
Cell chemical biology 28 (6), 866-875. e5, 2021
332021
Chemoproteomics of an Indole-Based Quinone Epoxide Identifies Druggable Vulnerabilities in Vancomycin-Resistant Staphylococcus aureus
A Kulkarni, I Soni, DS Kelkar, AT Dharmaraja, RK Sankar, G Beniwal, ...
Journal of medicinal chemistry 62 (14), 6785-6795, 2019
302019
Synthesis, thiol-mediated reactive oxygen species generation profiles and anti-proliferative activities of 2, 3-epoxy-1, 4-naphthoquinones
AT Dharmaraja, TK Dash, VB Konkimalla, H Chakrapani
MedChemComm 3 (2), 219-224, 2012
212012
Synthesis, reactive oxygen species generation and copper-mediated nuclease activity profiles of 2-aryl-3-amino-1, 4-naphthoquinones
VS Khodade, AT Dharmaraja, H Chakrapani
Bioorganic & medicinal chemistry letters 22 (11), 3766-3769, 2012
202012
Enhancers of human and rodent oligodendrocyte formation predominantly induce cholesterol precursor accumulation
JL Sax, SN Hershman, Z Hubler, D Allimuthu, MS Elitt, I Bederman, ...
ACS chemical biology 17 (8), 2188-2200, 2022
162022
Substituent effects on reactive oxygen species (ROS) generation by hydroquinones
AT Dharmaraja, C Jain, H Chakrapani
The Journal of Organic Chemistry 79 (19), 9413-9417, 2014
142014
Screening reveals sterol derivatives with pro-differentiation, pro-survival, or potent cytotoxic effects on oligodendrocyte progenitor cells
JL Sax, Z Hubler, D Allimuthu, DJ Adams
ACS Chemical Biology 16 (7), 1288-1297, 2021
132021
A phenacrylate scaffold for tunable thiol activation and release
RK Sankar, RS Kumbhare, AT Dharmaraja, H Chakrapani
Chemical Communications 50 (97), 15323-15326, 2014
132014
Redox modulator iron complexes trigger intrinsic apoptosis pathway in cancer cells
SK Vechalapu, R Kumar, N Chatterjee, S Gupta, S Khanna, ...
Iscience 27 (6), 2024
72024
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Articles 1–20