| DNA damage triggers a prolonged p53-dependent G1 arrest and long-term induction of Cip1 in normal human fibroblasts. A Di Leonardo, SP Linke, K Clarkin, GM Wahl Genes & development 8 (21), 2540-2551, 1994 | 1680 | 1994 |
| A reversible, p53-dependent G0/G1 cell cycle arrest induced by ribonucleotide depletion in the absence of detectable DNA damage. SP Linke, KC Clarkin, A Di Leonardo, A Tsou, GM Wahl Genes & development 10 (8), 934-947, 1996 | 731 | 1996 |
| DNA rereplication in the presence of mitotic spindle inhibitors in human and mouse fibroblasts lacking either p53 or pRb function AD Leonardo, SH Khan, SP Linke, V Greco, G Seidita, GM Wahl Cancer research 57 (6), 1013-1019, 1997 | 284 | 1997 |
| CENPA overexpression promotes genome instability in pRb-depleted human cells A Amato, T Schillaci, L Lentini, A Di Leonardo Molecular cancer 8 (1), 119, 2009 | 163 | 2009 |
| The mitotic kinase Aurora-A promotes distant metastases by inducing epithelial-to-mesenchymal transition in ERα+ breast cancer cells AB D'assoro, C Quatraro, A Amato, M Opyrchal, A Leontovich, Y Ikeda, ... Oncogene 33 (5), 599-610, 2014 | 148 | 2014 |
| Toward a rationale for the PTC124 (Ataluren) promoted readthrough of premature stop codons: a computational approach and GFP-reporter cell-based assay L Lentini, R Melfi, A Di Leonardo, A Spinello, G Barone, A Pace, ... Molecular pharmaceutics 11 (3), 653-664, 2014 | 112 | 2014 |
| RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts F Iovino, L Lentini, A Amato, A Di Leonardo Molecular cancer 5 (1), 38, 2006 | 109 | 2006 |
| NOTCH3 expression is linked to breast cancer seeding and distant metastasis AA Leontovich, M Jalalirad, JL Salisbury, L Mills, C Haddox, M Schroeder, ... Breast Cancer Research 20 (1), 105, 2018 | 91 | 2018 |
| Enhancement of premature stop codon readthrough in the CFTR gene by Ataluren (PTC124) derivatives I Pibiri, L Lentini, R Melfi, G Gallucci, A Pace, A Spinello, G Barone, ... European journal of medicinal chemistry 101, 236-244, 2015 | 75 | 2015 |
| Simultaneous Aurora-A/STK15 overexpression and centrosome amplification induce chromosomal instability in tumour cells with a MIN phenotype L Lentini, A Amato, T Schillaci, A Di Leonardo BMC cancer 7 (1), 212, 2007 | 72 | 2007 |
| Strategies against nonsense: oxadiazoles as translational readthrough-inducing drugs (TRIDs) A Campofelice, L Lentini, A Di Leonardo, R Melfi, M Tutone, A Pace, ... International journal of molecular sciences 20 (13), 3329, 2019 | 62 | 2019 |
| RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation A Amato, L Lentini, T Schillaci, F Iovino, A Di Leonardo BMC cell biology 10 (1), 79, 2009 | 59 | 2009 |
| MAD2 depletion triggers premature cellular senescence in human primary fibroblasts by activating a p53 pathway preventing aneuploid cells propagation L Lentini, V Barra, T Schillaci, A Di Leonardo Journal of cellular physiology 227 (9), 3324-3332, 2012 | 47 | 2012 |
| Exploring the readthrough of nonsense mutations by non-acidic Ataluren analogues selected by ligand-based virtual screening I Pibiri, L Lentini, M Tutone, R Melfi, A Pace, A Di Leonardo European Journal of Medicinal Chemistry 122, 429-435, 2016 | 44 | 2016 |
| Rescuing the CFTR protein function: Introducing 1, 3, 4-oxadiazoles as translational readthrough inducing drugs I Pibiri, L Lentini, R Melfi, M Tutone, S Baldassano, PR Galluzzo, ... European journal of medicinal chemistry 159, 126-142, 2018 | 42 | 2018 |
| DNA demethylation caused by 5-Aza-2′-deoxycytidine induces mitotic alterations and aneuploidy G Costa, V Barra, L Lentini, D Cilluffo, A Di Leonardo Oncotarget 7 (4), 3726, 2016 | 42 | 2016 |
| Bypass of cell cycle arrest induced by transient DNMT1 post-transcriptional silencing triggers aneuploidy in human cells V Barra, T Schillaci, L Lentini, G Costa, A Di Leonardo Cell division 7 (1), 2, 2012 | 42 | 2012 |
| Expression of the kinetochore protein Hec1 during the cell cycle in normal and cancer cells and its regulation by the pRb pathway C Ferretti, P Totta, M Fiore, M Mattiuzzo, T Schillaci, R Ricordye, ... Cell Cycle 9 (20), 4174-4182, 2010 | 42 | 2010 |
| Retinoblastoma epidemiology: Does the evidence matter? D Mastrangelo, S De Francesco, A Di Leonardo, L Lentini, ... European Journal of Cancer 43 (10), 1596-1603, 2007 | 42 | 2007 |
| P14ARF: The Absence that Makes the Difference D Cilluffo, V Barra, A Di Leonardo Genes 11 (7), 824, 2020 | 37 | 2020 |
Geoff WahlProfessor, Gene Expression Lab, Salk InstituteVerified email at salk.edu
