| Precision medicine integrating whole-genome sequencing, comprehensive metabolomics, and advanced imaging YCC Hou, HC Yu, R Martin, ET Cirulli, NM Schenker-Ahmed, M Hicks, ... Proceedings of the National Academy of Sciences 117 (6), 3053-3062, 2020 | 141 | 2020 |
| Analysis of postmarketing safety data for proton-pump inhibitors reveals increased propensity for renal injury, electrolyte abnormalities, and nephrolithiasis T Makunts, IV Cohen, L Awdishu, R Abagyan Scientific reports 9 (1), 2282, 2019 | 102 | 2019 |
| An unsupervised learning approach to identify novel signatures of health and disease from multimodal data I Shomorony, ET Cirulli, L Huang, LA Napier, RR Heister, M Hicks, ... Genome medicine 12 (1), 7, 2020 | 62 | 2020 |
| Myocarditis occurrence with cancer immunotherapy across indications in clinical trial and post-marketing data T Makunts, IM Saunders, IV Cohen, M Li, T Moumedjian, MA Issa, ... Scientific reports 11 (1), 17324, 2021 | 52 | 2021 |
| Acetaminophen (paracetamol) use modifies the sulfation of sex hormones IV Cohen, ET Cirulli, MW Mitchell, TJ Jonsson, J Yu, N Shah, TD Spector, ... EBioMedicine 28, 316-323, 2018 | 43 | 2018 |
| Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications IV Cohen, T Makunts, R Atayee, R Abagyan Scientific reports 7 (1), 1450, 2017 | 37 | 2017 |
| Concomitant drugs associated with increased mortality for MDMA users reported in a drug safety surveillance database IV Cohen, T Makunts, R Abagyan, K Thomas Scientific Reports 11 (1), 5997, 2021 | 32 | 2021 |
| Population scale retrospective analysis reveals distinctive antidepressant and anxiolytic effects of diclofenac, ketoprofen and naproxen in patients with pain T Makunts, IV Cohen, KC Lee, R Abagyan PLoS One 13 (4), e0195521, 2018 | 24 | 2018 |
| Cardiac adverse events associated with chloroquine and hydroxychloroquine exposure in 20 years of drug safety surveillance reports IV Cohen, T Makunts, T Moumedjian, MA Issa, R Abagyan Scientific reports 10 (1), 19199, 2020 | 22 | 2020 |
| The integrated stress response is modulated by eIF2B Agonist DNL343: results from phase 1 healthy subject and phase 1b ALS patient studies.(P8-8.010) L Sun, R Tsai, E Yulyaningsih, M Fanok, M Vissers, J Heuberger, B Flores, ... Neurology 100 (17_supplement_2), 3555, 2023 | 8 | 2023 |
| Precision medicine advancements using whole genome sequencing, noninvasive whole body imaging, and functional diagnostics YCC Hou, HC Yu, R Martin, NM Schenker-Ahmed, M Hicks, ET Cirulli, ... BioRxiv, 497560, 2018 | 6 | 2018 |
| Safety and pharmacokinetics of single ascending doses of TAK‐594/DNL593, a brain‐penetrant progranulin replacement therapy, in healthy volunteers: Interim results from Part A … AC Berger, I Cohen, M Jafarnejad, CL Chiu, A Bhalla, L Damo, ... Alzheimer's & Dementia 19, e075068, 2023 | 4 | 2023 |
| Determinants of cardiac adverse events of chloroquine and hydroxychloroquine in 20 years of drug safety surveillance reports IV Cohen, T Makunts, T Moumedjian, M Issa, R Abagyan medRxiv, 2020.05. 19.20107227, 2020 | 4 | 2020 |
| Unsupervised integration of multimodal dataset identifies novel signatures of health and disease I Shomorony, ET Cirulli, L Huang, LA Napier, RR Heister, M Hicks, ... BioRxiv, 432641, 2018 | 4 | 2018 |
| Inpatient pain alleviation after orthopaedic trauma surgery—are we doing a good job? MT Marmor, V Mahadevan, BP Solans, A Floren, L Jarlsberg, I Cohen, ... European Journal of Orthopaedic Surgery & Traumatology 34 (1), 569-576, 2024 | 3 | 2024 |
| Investigational eIF2B activator DNL343 modulates the integrated stress response in preclinical models of TDP-43 pathology and individuals with ALS in a randomized clinical trial BN Flores, SB Yu, IV Cohen, MH Fanok, W Luan, RD Maciuca, LD Sun, ... Nature Communications 16 (1), 7690, 2025 | 2 | 2025 |
| POPULATION PHARMACOKINETICS OF ISONIAZID IN TBTC STUDY 31/ACTG A5349 M Imperial, I Cohen, R Savic CLINICAL PHARMACOLOGY & THERAPEUTICS 113, S11-S11, 2023 | | 2023 |
| Three regulatory compliant test systems show no signs of MDMA-related genotoxicity IV Cohen, L Barber, TP Dubnicka, SB Hurtado, SA Tincher, ... Journal of Psychopharmacology 35 (11), 1431-1434, 2021 | | 2021 |
Ruben AbagyanUniversity of California, San DiegoVerified email at health.ucsd.edu
