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Lei He
Lei He
Genmab
Verified email at genmab.com
Title
Cited by
Cited by
Year
PI3K inhibition impairs BRCA1/2 expression and sensitizes BRCA proficient triple negative breast cancer to PARP inhibition
YH Ibrahim, C García-García, V Serra, L He, K Torres-Lockhart, A Prat, ...
Cancer Discovery, 2012
6752012
TBCRC009: a multicenter phase II clinical trial of platinum monotherapy with biomarker assessment in metastatic triple-negative breast cancer
SJ Isakoff, EL Mayer, L He, TA Traina, LA Carey, KJ Krag, HS Rugo, ...
Journal of clinical oncology 33 (17), 1902-1909, 2015
5132015
Analysis and update of the human solute carrier (SLC) gene superfamily
L He, K Vasiliou, DW Nebert
Hum Genomics 3 (2), 195-206, 2009
4612009
Slc39a14 gene encodes ZIP14, a metal/bicarbonate symporter: similarities to the ZIP8 transporter
K Girijashanker, L He, M Soleimani, JM Reed, H Li, Z Liu, B Wang, ...
Molecular pharmacology 73 (5), 1413-1423, 2008
4252008
ZIP8, member of the solute-carrier-39 (SLC39) metal-transporter family: characterization of transporter properties
L He, K Girijashanker, TP Dalton, J Reed, H Li, M Soleimani, DW Nebert
Molecular pharmacology 70 (1), 171-180, 2006
4242006
Identification of mouse SLC39A8 as the transporter responsible for cadmium-induced toxicity in the testis
TP Dalton, L He, B Wang, ML Miller, L Jin, KF Stringer, X Chang, ...
Proceedings of the National Academy of Sciences 102 (9), 3401-3406, 2005
3562005
Cd2+ versus Zn2+ uptake by the ZIP8 HCO3--dependent symporter: kinetics, electrogenicity and trafficking
Z Liu, H Li, M Soleimani, K Girijashanker, JM Reed, L He, TP Dalton, ...
Biochemical and biophysical research communications 365 (4), 814-820, 2008
2122008
Discovery of ZIP transporters that participate in cadmium damage to testis and kidney
L He, B Wang, EB Hay, DW Nebert
Toxicology and applied pharmacology 238 (3), 250-257, 2009
1602009
Enhanced cadmium-induced testicular necrosis and renal proximal tubule damage caused by gene-dose increase in a Slc39a8-transgenic mouse line
B Wang, SN Schneider, N Dragin, K Girijashanker, TP Dalton, L He, ...
American Journal of Physiology-Cell Physiology 292 (4), C1523-C1535, 2007
1372007
Physical association of HDAC1 and HDAC2 with p63 mediates transcriptional repression and tumor maintenance in squamous cell carcinoma
MR Ramsey, L He, N Forster, B Ory, LW Ellisen
Cancer research 71 (13), 4373-4379, 2011
1282011
ZIP8 Zinc Transporter: Indispensable Role for Both Multiple-Organ Organogenesis and Hematopoiesis In Utero
M Gálvez-Peralta, L He, LF Jorge-Nebert, B Wang, ML Miller, BL Eppert, ...
PloS one 7 (5), e36055, 2012
1162012
Mcl-1 and FBW7 control a dominant survival pathway underlying HDAC and Bcl-2 inhibitor synergy in squamous cell carcinoma
L He, K Torres-Lockhart, N Forster, S Ramakrishnan, P Greninger, ...
Cancer Discovery, 2012
802012
Safety and tolerability of veliparib combined with capecitabine plus radiotherapy in patients with locally advanced rectal cancer: a phase 1b study.
MM Czito BG, Deming DA, Jameson GS, Mulcahy MF, Vaghefi H, Dudley MW, Holen ...
Lancet Gastroenterol Hepatol., 2017
782017
Veliparib in combination with carboplatin and etoposide in patients with treatment-naïve extensive-stage small cell lung cancer: a phase 2 randomized study
LA Byers, D Bentsion, S Gans, K Penkov, CH Son, A Sibille, ...
Clinical Cancer Research 27 (14), 3884-3895, 2021
772021
ZIP14 and ZIP8 zinc/bicarbonate symporters in Xenopus oocytes: characterization of metal uptake and inhibition
DW Nebert, M Gálvez-Peralta, EB Hay, H Li, E Johansson, C Yin, B Wang, ...
Metallomics, 2012
732012
A role for BRCA1 in uterine leiomyosarcoma
D Xing, G Scangas, M Nitta, L He, X Xu, YJM Ioffe, PJ Aspuria, CY Hedvat, ...
Cancer research 69 (21), 8231-8235, 2009
632009
BRCA1-associated epigenetic regulation of p73 mediates an effector pathway for chemosensitivity in ovarian carcinoma
N Ibrahim, L He, CO Leong, D Xing, BY Karlan, EM Swisher, BR Rueda, ...
Cancer research 70 (18), 7155-7165, 2010
562010
Veliparib in combination with platinum-based chemotherapy for first-line treatment of advanced squamous cell lung cancer: a randomized, multicenter phase III study
SS Ramalingam, S Novello, SZ Guclu, D Bentsion, Z Zvirbule, M Szilasi, ...
Journal of Clinical Oncology 39 (32), 3633-3644, 2021
532021
A phase I dose-escalation study of veliparib combined with carboplatin and etoposide in patients with extensive-stage small cell lung cancer and other solid tumors
F Atrafi, HJM Groen, LA Byers, E Garralda, MP Lolkema, RS Sangha, ...
Clinical Cancer Research 25 (2), 496-505, 2019
512019
Generation of a Slc39a8 hypomorph mouse: Markedly decreased ZIP8 Zn 2+/transporter expression
B Wang, L He, H Dong, TP Dalton, DW Nebert
Biochemical and Biophysical Research Communications 410 (2), 289-294, 2011
502011
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Articles 1–20