| The RNA World: molecular cooperation at the origins of life PG Higgs, N Lehman Nature Reviews Genetics 16 (1), 7-17, 2015 | 708 | 2015 |
| Theory of polyampholyte solutions PG Higgs, JF Joanny The Journal of chemical physics 94 (2), 1543-1554, 1991 | 503 | 1991 |
| RNA secondary structure: physical and computational aspects PG Higgs Quarterly reviews of biophysics 33 (3), 199-253, 2000 | 410 | 2000 |
| The influence of predator–prey population dynamics on the long-term evolution of food web structure B Drossel, PG Higgs, AJ McKane Journal of Theoretical Biology 208 (1), 91-107, 2001 | 311 | 2001 |
| Modelling coevolution in multispecies communities G Caldarelli, PG Higgs, AJ McKane Journal of theoretical biology 193 (2), 345-358, 1998 | 264 | 1998 |
| A thermodynamic basis for prebiotic amino acid synthesis and the nature of the first genetic code PG Higgs, RE Pudritz Astrobiology 9 (5), 483-490, 2009 | 261 | 2009 |
| A comprehensive analysis of mammalian mitochondrial genome base composition and improved phylogenetic methods A Gibson, V Gowri-Shankar, PG Higgs, M Rattray Molecular Biology and Evolution 22 (2), 251-264, 2005 | 216 | 2005 |
| Bioinformatics and molecular evolution PG Higgs, TK Attwood John Wiley & Sons, 2013 | 199 | 2013 |
| RNA-based phylogenetic methods: application to mammalian mitochondrial RNA sequences C Hudelot, V Gowri-Shankar, H Jow, M Rattray, PG Higgs Molecular Phylogenetics and Evolution 28 (2), 241-252, 2003 | 198 | 2003 |
| Bayesian phylogenetics using an RNA substitution model applied to early mammalian evolution H Jow, C Hudelot, M Rattray, PG Higgs Molecular Biology and Evolution 19 (9), 1591-1601, 2002 | 198 | 2002 |
| RNA sequence evolution with secondary structure constraints: comparison of substitution rate models using maximum-likelihood methods NJ Savill, DC Hoyle, PG Higgs Genetics 157 (1), 399-411, 2001 | 198 | 2001 |
| Coevolution of codon usage and tRNA genes leads to alternative stable states of biased codon usage PG Higgs, W Ran Molecular biology and evolution 25 (11), 2279-2291, 2008 | 193 | 2008 |
| Codon usage in mitochondrial genomes: distinguishing context-dependent mutation from translational selection W Jia, PG Higgs Molecular biology and evolution 25 (2), 339-351, 2008 | 183 | 2008 |
| Constraining the time interval for the origin of life on Earth BKD Pearce, AS Tupper, RE Pudritz, PG Higgs Astrobiology 18 (3), 343-364, 2018 | 171 | 2018 |
| Population evolution on a multiplicative single-peak fitness landscape G Woodcock, PG Higgs Journal of theoretical biology 179 (1), 61-73, 1996 | 161 | 1996 |
| A four-column theory for the origin of the genetic code: tracing the evolutionary pathways that gave rise to an optimized code PG Higgs Biology direct 4 (1), 16, 2009 | 154 | 2009 |
| The relationship between the rate of molecular evolution and the rate of genome rearrangement in animal mitochondrial genomes W Xu, D Jameson, B Tang, PG Higgs Journal of molecular evolution 63 (3), 375-392, 2006 | 152 | 2006 |
| Genetic distance and species formation in evolving populations PG Higgs, B Derrida Journal of molecular evolution 35 (5), 454-465, 1992 | 146 | 1992 |
| The mechanisms of codon reassignments in mitochondrial genetic codes S Sengupta, X Yang, PG Higgs Journal of molecular evolution 64 (6), 662-688, 2007 | 145 | 2007 |
| The advantages and disadvantages of horizontal gene transfer and the emergence of the first species AA Vogan, PG Higgs Biology direct 6 (1), 1, 2011 | 127 | 2011 |
