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Michele F.M. Sciacca
Michele F.M. Sciacca
CNR- Istituto di Cristallografia
Verified email at cnr.it
Title
Cited by
Cited by
Year
Two-step mechanism of membrane disruption by Aβ through membrane fragmentation and pore formation
MFM Sciacca, SA Kotler, JR Brender, J Chen, D Lee, A Ramamoorthy
Biophysical journal 103 (4), 702-710, 2012
4242012
Amyloid growth and membrane damage: Current themes and emerging perspectives from theory and experiments on Aβ and hIAPP
MFM Sciacca, C Tempra, F Scollo, D Milardi, C La Rosa
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1625-1638, 2018
1552018
Lipid-chaperone hypothesis: A common molecular mechanism of membrane disruption by intrinsically disordered proteins
MF Sciacca, F Lolicato, C Tempra, F Scollo, BR Sahoo, MD Watson, ...
ACS chemical neuroscience 11 (24), 4336-4350, 2020
1472020
Cations as switches of amyloid-mediated membrane disruption mechanisms: calcium and IAPP
MFM Sciacca, D Milardi, GML Messina, G Marletta, JR Brender, ...
Biophysical Journal 104 (1), 173-184, 2013
1292013
Phosphatidylethanolamine enhances amyloid fiber dependent membrane fragmentation
MFM Sciacca, JR Brender, DK Lee, A Ramamoorthy
Biophysical Journal 102 (3), 488a, 2012
1282012
Does cholesterol suppress the antimicrobial peptide induced disruption of lipid raft containing membranes?
AJ McHenry, MFM Sciacca, JR Brender, A Ramamoorthy
Biochimica et Biophysica Acta (BBA)-Biomembranes 1818 (12), 3019-3024, 2012
1142012
Probing the Sources of the Apparent Irreproducibility of Amyloid Formation: Drastic Changes in Kinetics and a Switch in Mechanism due to Micelle-Like Oligomer Formation at …
AR Jeffrey R Brender, Janarthanan Krishnamoorthy, Michele Francesco Maria ...
The Journal of Physical Chemistry B, 2015
1102015
The role of cholesterol in driving IAPP-membrane interactions
MFM Sciacca, F Lolicato, G Di Mauro, D Milardi, L D’Urso, C Satriano, ...
Biophysical journal 111 (1), 140-151, 2016
1032016
Inhibition of Aβ amyloid growth and toxicity by silybins: The crucial role of stereochemistry
MFM Sciacca, V Romanucci, A Zarrelli, I Monaco, F Lolicato, N Spinella, ...
ACS chemical neuroscience 8 (8), 1767-1778, 2017
932017
Phospholipids critical micellar concentrations trigger different mechanisms of intrinsically disordered proteins interaction with model membranes
F Scollo, C Tempra, F Lolicato, MFM Sciacca, A Raudino, D Milardi, ...
The journal of physical chemistry letters 9 (17), 5125-5129, 2018
922018
Lipid composition-dependent membrane fragmentation and pore-forming mechanisms of membrane disruption by pexiganan (MSI-78)
DK Lee, JR Brender, MFM Sciacca, J Krishnamoorthy, C Yu, ...
Biochemistry 52 (19), 3254-3263, 2013
812013
Extracellular truncated tau causes early presynaptic dysfunction associated with Alzheimer’s disease and other tauopathies
F Florenzano, C Veronica, G Ciasca, MT Ciotti, A Pittaluga, G Olivero, ...
Oncotarget 8 (39), 64745, 2017
642017
The role of aromatic side-chains in amyloid growth and membrane interaction of the islet amyloid polypeptide fragment LANFLVH
D Milardi, MFM Sciacca, M Pappalardo, DM Grasso, C La Rosa
European Biophysics Journal 40 (1), 1-12, 2011
592011
Self-assembling pathway of HiApp fibrils within lipid bilayers
S Scalisi, MFM Sciacca, G Zhavnerko, DM Grasso, G Marletta, C La Rosa
ChemBioChem 11 (13), 1856-1859, 2010
472010
A blend of two resveratrol derivatives abolishes hIAPP amyloid growth and membrane damage
MFM Sciacca, R Chillemi, S Sciuto, V Greco, C Messineo, SA Kotler, ...
Biochimica et Biophysica Acta (BBA)-Biomembranes 1860 (9), 1793-1802, 2018
462018
Calcium-activated membrane interaction of the islet amyloid polypeptide: Implications in the pathogenesis of type II diabetes mellitus
MFM Sciacca, M Pappalardo, D Milardi, DM Grasso, C La Rosa
Archives of biochemistry and biophysics 477 (2), 291-298, 2008
462008
Non-selective ion channel activity of polymorphic human islet amyloid polypeptide (amylin) double channels
J Zhao, R Hu, MFM Sciacca, JR Brender, H Chen, A Ramamoorthy, ...
Physical Chemistry Chemical Physics 16 (6), 2368-2377, 2014
432014
The active role of Ca 2+ ions in Aβ-mediated membrane damage
MFM Sciacca, I Monaco, C La Rosa, D Milardi
Chemical Communications 54 (29), 3629-3631, 2018
412018
Membrane interactions and conformational preferences of human and avian prion N-terminal tandem repeats: the role of copper (II) ions, pH, and membrane mimicking environments
G Di Natale, G Pappalardo, D Milardi, MFM Sciacca, F Attanasio, ...
The Journal of Physical Chemistry B 114 (43), 13830-13838, 2010
412010
Aβ and Tau interact with metal ions, lipid membranes and peptide-based amyloid inhibitors: are these common features relevant in Alzheimer’s disease?
G Di Natale, G Sabatino, MFM Sciacca, R Tosto, D Milardi, G Pappalardo
Molecules 27 (16), 5066, 2022
402022
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Articles 1–20