| 3′ UTR seed matches, but not overall identity, are associated with RNAi off-targets A Birmingham, EM Anderson, A Reynolds, D Ilsley-Tyree, D Leake, ... Nature methods 3 (3), 199-204, 2006 | 1278 | 2006 |
| Off-target effects by siRNA can induce toxic phenotype Y Fedorov, EM Anderson, A Birmingham, A Reynolds, J Karpilow, ... Rna 12 (7), 1188-1196, 2006 | 727 | 2006 |
| Induction of the interferon response by siRNA is cell type–and duplex length–dependent A Reynolds, EM Anderson, A Vermeulen, Y Fedorov, K Robinson, ... Rna 12 (6), 988-993, 2006 | 468 | 2006 |
| ERK1/2 is required for myoblast proliferation but is dispensable for muscle gene expression and cell fusion NC Jones, YV Fedorov, RS Rosenthal, BB Olwin Journal of cellular physiology 186 (1), 104-115, 2001 | 358 | 2001 |
| The p38α/β MAPK functions as a molecular switch to activate the quiescent satellite cell NC Jones, KJ Tyner, L Nibarger, HM Stanley, DDW Cornelison, ... The Journal of cell biology 169 (1), 105-116, 2005 | 350 | 2005 |
| Coordination of satellite cell activation and self-renewal by Par-complex-dependent asymmetric activation of p38α/β MAPK A Troy, AB Cadwallader, Y Fedorov, K Tyner, KK Tanaka, BB Olwin Cell stem cell 11 (4), 541-553, 2012 | 332 | 2012 |
| Accumulation of 8, 9-unsaturated sterols drives oligodendrocyte formation and remyelination Z Hubler, D Allimuthu, I Bederman, MS Elitt, M Madhavan, KC Allan, ... Nature 560 (7718), 372-376, 2018 | 241 | 2018 |
| Functional profiling reveals critical role for miRNA in differentiation of human mesenchymal stem cells A Schoolmeesters, T Eklund, D Leake, A Vermeulen, Q Smith, ... PloS one 4 (5), e5605, 2009 | 237 | 2009 |
| Modified polynucleotides for reducing off-target effects in RNA interference D Leake, A Reynolds, A Khvorova, W Marshall, PS Linsley US Patent 7,595,387, 2009 | 229 | 2009 |
| Experimental validation of the importance of seed complement frequency to siRNA specificity EM Anderson, A Birmingham, S Baskerville, A Reynolds, E Maksimova, ... Rna 14 (5), 853-861, 2008 | 196 | 2008 |
| Different delivery methods—different expression profiles Y Fedorov, A King, E Anderson, J Karpilow, D Ilsley, W Marshall, ... Nature methods 2 (4), 241-241, 2005 | 103 | 2005 |
| Assessment of Cr (VI)-induced cytotoxicity and genotoxicity using high content analysis CM Thompson, Y Fedorov, DD Brown, M Suh, DM Proctor, L Kuriakose, ... Public Library of Science 7 (8), e42720, 2012 | 89 | 2012 |
| Modified polynucleotides for use in rna interference D Leake, A Reynolds, A Khvorova, W Marshall, Y Fedorov, K Nichols US Patent App. 11/619,993, 2007 | 74 | 2007 |
| Regulation of myogenesis by fibroblast growth factors requires beta-gamma subunits of pertussis toxin-sensitive G proteins YV Fedorov, NC Jones, BB Olwin Molecular and cellular biology 18 (10), 5780-5787, 1998 | 74 | 1998 |
| SNP discriminatory siRNA Y Fedorov, A Reynolds, A Khvorova US Patent App. 11/043,637, 2005 | 53 | 2005 |
| Modified polynucleotides for use in rna interference D Leake, A Reynolds, A Khvorova, W Marshall, Y Fedorov, K Nichols US Patent App. 10/551,350, 2007 | 49 | 2007 |
| Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington’s disease D Hu, X Sun, A Magpusao, Y Fedorov, M Thompson, B Wang, K Lundberg, ... Nature communications 12 (1), 5305, 2021 | 47 | 2021 |
| Stabilized siRNAs as transfection controls and silencing reagents D Leake, A Khvorova, Y Fedorov, M Delaney, B Robertson, E Anderson, ... US Patent App. 11/051,195, 2007 | 47 | 2007 |
| Pervasive environmental chemicals impair oligodendrocyte development EF Cohn, BLL Clayton, M Madhavan, KA Lee, S Yacoub, Y Fedorov, ... Nature neuroscience 27 (5), 836-845, 2024 | 44 | 2024 |
| Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma I Bayles, M Krajewska, WD Pontius, A Saiakhova, JJ Morrow, C Bartels, ... The Journal of Clinical Investigation 129 (10), 4377-4392, 2019 | 44 | 2019 |