| Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes Y Tanaka, G Suzuki, T Matsuwaki, M Hosokawa, G Serrano, TG Beach, ... Human molecular genetics 26 (5), 969-988, 2017 | 210 | 2017 |
| Bovine C-terminal octapeptide of RFamide-related peptide-3 suppresses luteinizing hormone (LH) secretion from the pituitary as well as pulsatile LH secretion in bovines H Kadokawa, M Shibata, Y Tanaka, T Kojima, K Matsumoto, K Oshima, ... Domestic animal endocrinology 36 (4), 219-224, 2009 | 182 | 2009 |
| Possible involvement of lysosomal dysfunction in pathological changes of the brain in aged progranulin-deficient mice Y Tanaka, JK Chambers, T Matsuwaki, K Yamanouchi, M Nishihara Acta neuropathologica communications 2 (1), 78, 2014 | 171 | 2014 |
| Increased lysosomal biogenesis in activated microglia and exacerbated neuronal damage after traumatic brain injury in progranulin-deficient mice Y Tanaka, T Matsuwaki, K Yamanouchi, M Nishihara Neuroscience 250, 8-19, 2013 | 162 | 2013 |
| Phosphorylation of TAR DNA-binding protein of 43 kDa (TDP-43) by truncated casein kinase 1δ triggers mislocalization and accumulation of TDP-43 T Nonaka, G Suzuki, Y Tanaka, F Kametani, S Hirai, H Okado, T Miyashita, ... Journal of Biological Chemistry 291 (11), 5473-5483, 2016 | 158 | 2016 |
| Exacerbated inflammatory responses related to activated microglia after traumatic brain injury in progranulin-deficient mice Y Tanaka, T Matsuwaki, K Yamanouchi, M Nishihara Neuroscience 231, 49-60, 2013 | 138 | 2013 |
| Multiple therapeutic effects of progranulin on experimental acute ischaemic stroke M Kanazawa, K Kawamura, T Takahashi, M Miura, Y Tanaka, M Koyama, ... Brain 138 (7), 1932-1948, 2015 | 128 | 2015 |
| Gain-of-function profilin 1 mutations linked to familial amyotrophic lateral sclerosis cause seed-dependent intracellular TDP-43 aggregation Y Tanaka, T Nonaka, G Suzuki, F Kametani, M Hasegawa Human molecular genetics 25 (7), 1420-1433, 2016 | 83 | 2016 |
| Profilin 1 mutants form aggregates that induce accumulation of prion-like TDP-43 Y Tanaka, M Hasegawa Prion 10 (4), 283-289, 2016 | 36 | 2016 |
| Progranulin haploinsufficiency reduces amyloid beta deposition in Alzheimer’s disease model mice M Hosokawa, Y Tanaka, T Arai, H Kondo, H Akiyama, M Hasegawa Experimental animals 67 (1), 63-70, 2018 | 24 | 2018 |
| Dysregulation of the progranulin-driven autophagy-lysosomal pathway mediates secretion of the nuclear protein TDP-43 Y Tanaka, S Ito, Y Honma, M Hasegawa, F Kametani, G Suzuki, ... Journal of Biological Chemistry 299 (11), 2023 | 21 | 2023 |
| Taurine counteracts the suppressive effect of lipopolysaccharide on neurogenesis in the hippocampus of rats G Wu, T Matsuwaki, Y Tanaka, K Yamanouchi, J Hu, M Nishihara Taurine 8: Volume 1: The Nervous System, Immune System, Diabetes and the …, 2013 | 16 | 2013 |
| Kinase activity-tagged western blotting assay M Eto, S Katsuki, Y Tanaka, K Takeya BioTechniques 68 (4), 211-213, 2020 | 9 | 2020 |
| TDP-43 secretion via extracellular vesicles is regulated by macroautophagy Y Tanaka, S Ito, G Suzuki Autophagy Reports 3 (1), 2291250, 2024 | 8 | 2024 |
| Overexpression of progranulin increases pathological protein accumulation by suppressing autophagic flux Y Tanaka, S Kusumoto, Y Honma, K Takeya, M Eto Biochemical and Biophysical Research Communications 611, 78-84, 2022 | 8 | 2022 |
| Evaluation of LC3-II release via extracellular vesicles in relation to the accumulation of intracellular LC3-positive vesicles S Ito, Y Tanaka Journal of Visualized Experiments (JoVE), e67385, 2024 | 5 | 2024 |
| Abemaciclib and Vacuolin-1 induce vacuole-like autolysosome formation–A new tool to study autophagosome-lysosome fusion Y Tanaka, H Hino, K Takeya, M Eto Biochemical and Biophysical Research Communications 614, 191-197, 2022 | 5 | 2022 |
| Possible roles of N-and C-terminal unstructured tails of CPI-17 in regulating Ca2+ sensitization force of smooth muscle M Eto, S Katsuki, M Ohashi, Y Miyagawa, Y Tanaka, K Takeya, T Kitazawa Journal of Smooth Muscle Research 58, 22-33, 2022 | 5 | 2022 |
| PHI-1, an Endogenous Inhibitor Protein for Protein Phosphatase-1 and a Pan-Cancer Marker, Regulates Raf-1 Proteostasis JA Kirkbride, GY Nilsson, JI Kim, K Takeya, Y Tanaka, H Tokumitsu, ... Biomolecules 13 (12), 1741, 2023 | 3 | 2023 |
| Abemaciclib and Vacuolin-1 decrease aggregate-prone TDP-43 accumulation by accelerating autophagic flux Y Tanaka, L Kozuma, H Hino, K Takeya, M Eto Biochemistry and Biophysics Reports 38, 101705, 2024 | 2 | 2024 |
