| Co-delivery of HIF1α siRNA and gemcitabine via biocompatible lipid-polymer hybrid nanoparticles for effective treatment of pancreatic cancer X Zhao, F Li, Y Li, H Wang, H Ren, J Chen, G Nie, J Hao Biomaterials 46, 13-25, 2015 | 295 | 2015 |
| Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism K Chen, D Wang, WT Du, ZB Han, H Ren, Y Chi, SG Yang, D Zhu, ... Clinical immunology 135 (3), 448-458, 2010 | 282 | 2010 |
| Inducing enhanced immunogenic cell death with nanocarrier-based drug delivery systems for pancreatic cancer therapy X Zhao, K Yang, R Zhao, T Ji, X Wang, X Yang, Y Zhang, K Cheng, S Liu, ... Biomaterials 102, 187-197, 2016 | 275 | 2016 |
| Type 1 and type 2 T-cell profiles in idiopathic thrombocytopenic purpura T Wang, H Zhao, H Ren, J Guo, M Xu, R Yang, ZC Han Haematologica 90 (7), 914-923, 2005 | 253 | 2005 |
| Cancer-FOXP3 directly activated CCL5 to recruit FOXP3+ Treg cells in pancreatic ductal adenocarcinoma X Wang, M Lang, T Zhao, X Feng, C Zheng, C Huang, J Hao, J Dong, ... Oncogene 36 (21), 3048-3058, 2017 | 252 | 2017 |
| Hypoxia-inducible factor-1 promotes pancreatic ductal adenocarcinoma invasion and metastasis by activating transcription of the actin-bundling protein fascin X Zhao, S Gao, H Ren, W Sun, H Zhang, J Sun, S Yang, J Hao Cancer research 74 (9), 2455-2464, 2014 | 197 | 2014 |
| Inhibition of HIF-1α by PX-478 enhances the anti-tumor effect of gemcitabine by inducing immunogenic cell death in pancreatic ductal adenocarcinoma T Zhao, H Ren, L Jia, J Chen, W Xin, F Yan, J Li, X Wang, S Gao, D Qian, ... Oncotarget 6 (4), 2250, 2014 | 161 | 2014 |
| Hypoxia-inducible factor (HIF)-1α directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF) ZB Han, H Ren, H Zhao, Y Chi, K Chen, B Zhou, Y Liu, L Zhang, B Xu, ... Carcinogenesis 29 (10), 1853-1861, 2008 | 158 | 2008 |
| Tumour-derived Interleukin 35 promotes pancreatic ductal adenocarcinoma cell extravasation and metastasis by inducing ICAM1 expression C Huang, N Li, Z Li, A Chang, Y Chen, T Zhao, Y Li, X Wang, W Zhang, ... Nature communications 8 (1), 14035, 2017 | 150 | 2017 |
| PD-L1 is a direct target of cancer-FOXP3 in pancreatic ductal adenocarcinoma (PDAC), and combined immunotherapy with antibodies against PD-L1 and CCL5 is effective in the … X Wang, X Li, X Wei, H Jiang, C Lan, S Yang, H Wang, Y Yang, C Tian, ... Signal transduction and targeted therapy 5 (1), 38, 2020 | 134 | 2020 |
| Metabolic reprogramming and therapeutic resistance in primary and metastatic breast cancer S Liu, X Zhang, W Wang, X Li, X Sun, Y Zhao, Q Wang, Y Li, F Hu, H Ren Molecular Cancer 23 (1), 261, 2024 | 127 | 2024 |
| Human FOXP3 and tumour microenvironment J Wang, R Gong, C Zhao, K Lei, X Sun, H Ren Immunology 168 (2), 248-255, 2023 | 120 | 2023 |
| Interleukin 35 expression correlates with microvessel density in pancreatic ductal adenocarcinoma, recruits monocytes, and promotes growth and angiogenesis of xenograft tumors … C Huang, Z Li, N Li, Y Li, A Chang, T Zhao, X Wang, H Wang, S Gao, ... Gastroenterology 154 (3), 675-688, 2018 | 120 | 2018 |
| Injectable immunotherapeutic hydrogel containing RNA-loaded lipid nanoparticles reshapes tumor microenvironment for pancreatic cancer therapy C Gao, K Cheng, Y Li, R Gong, X Zhao, G Nie, H Ren Nano Letters 22 (22), 8801-8809, 2022 | 119 | 2022 |
| Hypoxia inducible factor 1 (HIF-1) recruits macrophage to activate pancreatic stellate cells in pancreatic ductal adenocarcinoma N Li, Y Li, Z Li, C Huang, Y Yang, M Lang, J Cao, W Jiang, Y Xu, J Dong, ... International journal of molecular sciences 17 (6), 799, 2016 | 118 | 2016 |
| Multiple layer‐by‐layer lipid‐polymer hybrid nanoparticles for improved FOLFIRINOX chemotherapy in pancreatic tumor models F Li, X Zhao, H Wang, R Zhao, T Ji, H Ren, GJ Anderson, G Nie, J Hao Advanced functional materials 25 (5), 788-798, 2015 | 116 | 2015 |
| LASP1 is a HIF1α target gene critical for metastasis of pancreatic cancer T Zhao, H Ren, J Li, J Chen, H Zhang, W Xin, Y Sun, L Sun, Y Yang, J Sun, ... Cancer research 75 (1), 111-119, 2015 | 115 | 2015 |
| IGFBP2 activates the NF-κB pathway to drive epithelial–mesenchymal transition and invasive character in pancreatic ductal adenocarcinoma S Gao, Y Sun, X Zhang, L Hu, Y Liu, CY Chua, LM Phillips, H Ren, ... Cancer research 76 (22), 6543-6554, 2016 | 114 | 2016 |
| Ectopic expression of the microtubule‐dependent motor protein Eg5 promotes pancreatic tumourigenesis M Liu, X Wang, Y Yang, D Li, H Ren, Q Zhu, Q Chen, S Han, J Hao, ... The Journal of pathology 221 (2), 221-228, 2010 | 108 | 2010 |
| Targeted co-delivery of the iron chelator deferoxamine and a HIF1α inhibitor impairs pancreatic tumor growth J Lang, X Zhao, X Wang, Y Zhao, Y Li, R Zhao, K Cheng, Y Li, X Han, ... ACS nano 13 (2), 2176-2189, 2019 | 97 | 2019 |
