| Selective anchoring of TFIID to nucleosomes by trimethylation of histone H3 lysine 4 M Vermeulen, KW Mulder, S Denissov, WWMP Pijnappel, ... Cell 131 (1), 58-69, 2007 | 1117 | 2007 |
| The Saccharomyces cerevisiae Set1 complex includes an Ash2 homologue and methylates histone 3 lysine 4 A Roguev, D Schaft, A Shevchenko, WWMP Pijnappel, M Wilm, ... The EMBO journal, 2001 | 747 | 2001 |
| The S. cerevisiae SET3 complex includes two histone deacetylases, Hos2 and Hst1, and is a meiotic-specific repressor of the sporulation gene program WWMP Pijnappel, D Schaft, A Roguev, A Shevchenko, H Tekotte, M Wilm, ... Genes & development 15 (22), 2991-3004, 2001 | 349 | 2001 |
| The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification WWM Pijnappel, HFJ Hendriks, GE Folkers, CE Van den Brink, EJ Dekker, ... Nature 366 (6453), 340-344, 1993 | 330 | 1993 |
| Human Ccr4–Not complexes contain variable deadenylase subunits NC Lau, A Kolkman, FMA van Schaik, KW Mulder, WWMP Pijnappel, ... Biochemical Journal 422 (3), 443-453, 2009 | 236 | 2009 |
| ATAC-king the complexity of SAGA during evolution G Spedale, HTM Timmers, WWMP Pijnappel Genes & development 26 (6), 527-541, 2012 | 225 | 2012 |
| European consensus for starting and stopping enzyme replacement therapy in adult patients with Pompe disease: a 10‐year experience AT van der Ploeg, ME Kruijshaar, A Toscano, P Laforêt, C Angelini, ... European journal of neurology 24 (6), 768-e31, 2017 | 195 | 2017 |
| Engineering the mouse genome with bacterial artificial chromosomes to create multipurpose alleles G Testa, Y Zhang, K Vintersten, V Benes, WWMP Pijnappel, I Chambers, ... Nature biotechnology 21 (4), 443-447, 2003 | 159 | 2003 |
| Opportunities and challenges for antisense oligonucleotide therapies EC Kuijper, AJ Bergsma, WWMP Pijnappel, A Aartsma‐Rus Journal of inherited metabolic disease 44 (1), 72-87, 2021 | 156 | 2021 |
| Ready for repair? Gene editing enters the clinic for the treatment of human disease MPT Ernst, M Broeders, P Herrero-Hernandez, E Oussoren, ... Molecular Therapy Methods & Clinical Development 18, 532-557, 2020 | 109 | 2020 |
| Elevated plasma cardiac troponin T levels caused by skeletal muscle damage in Pompe disease SCA Wens, GJ Schaaf, M Michels, ME Kruijshaar, TJM Van Gestel, ... Circulation: cardiovascular genetics 9 (1), 6-13, 2016 | 109 | 2016 |
| Large-scale expansion of human iPSC-derived skeletal muscle cells for disease modeling and cell-based therapeutic strategies E van der Wal, P Herrero-Hernandez, R Wan, M Broeders, ... Stem Cell Reports 10 (6), 1975-1990, 2018 | 107 | 2018 |
| Perturbation of the yeast N-acetyltransferase NatB induces elevation of protein phosphorylation levels AO Helbig, S Rosati, PWWM Pijnappel, B van Breukelen, MHTH Timmers, ... BMC genomics 11 (1), 685, 2010 | 107 | 2010 |
| Deciphering protein complexes and protein interaction networks by tandem affinity purification and mass spectrometry: analytical perspective A Shevchenko, D Schaft, A Roguev, WWMP Pijnappel, AF Stewart, ... Molecular & Cellular Proteomics 1 (3), 204-212, 2002 | 103 | 2002 |
| A central role for TFIID in the pluripotent transcription circuitry WWMP Pijnappel, D Esch, MPA Baltissen, G Wu, N Mischerikow, ... Nature 495 (7442), 516-519, 2013 | 102 | 2013 |
| Sharpening the molecular scissors: advances in gene-editing technology M Broeders, P Herrero-Hernandez, MPT Ernst, AT van der Ploeg, ... Iscience 23 (1), 2020 | 92 | 2020 |
| Noradrenaline release from streptolysin-O-permeated rat cortical synaptosomes: effects of calcium, phorbol esters, protein kinase inhibitors, and antibodies to the neuron … LV Dekker, PNE De Graan, P Pijnappel, AB Oestreicher, WH Gispen Journal of Neurochemistry 56, 1146-1153, 1991 | 92 | 1991 |
| Antisense oligonucleotides promote exon inclusion and correct the common c.-32-13T> G GAA splicing variant in Pompe disease E van der Wal, AJ Bergsma, JM Pijnenburg, AT van der Ploeg, ... Molecular Therapy Nucleic Acids 7, 90-100, 2017 | 87 | 2017 |
| Quantitative proteomics reveals regulation of dynamic components within TATA-binding protein (TBP) transcription complexes F Mousson, A Kolkman, WWMP Pijnappel, HTM Timmers, AJR Heck Molecular & Cellular Proteomics 7 (5), 845-852, 2008 | 82 | 2008 |
| GAA deficiency in Pompe disease is alleviated by exon inclusion in iPSC-derived skeletal muscle cells E Van Der Wal, AJ Bergsma, TJM Van Gestel, S LM, H Zaehres, ... Molecular Therapy Nucleic Acids 7, 101-115, 2017 | 77 | 2017 |
