| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 14604* | 2021 |
| Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 3080 | 2024 |
| Extracellular vesicles: Novel promising delivery systems for therapy of brain diseases D Rufino-Ramos, PR Albuquerque, V Carmona, R Perfeito, RJ Nobre, ... Journal of Controlled Release 262, 247-258, 2017 | 454 | 2017 |
| miR‐155 modulates microglia‐mediated immune response by down‐regulating SOCS‐1 and promoting cytokine and nitric oxide production AL Cardoso, JR Guedes, L Pereira de Almeida, MC Pedroso de Lima Immunology 135 (1), 73-88, 2012 | 390 | 2012 |
| Self-inactivating lentiviral vectors with enhanced transgene expression as potential gene transfer system in Parkinson's disease N Deglon, JL Tseng, JC Bensadoun, AD Zurn, Y Arsenijevic, ... Human gene therapy 11 (1), 179-190, 2000 | 358 | 2000 |
| Gene therapy for the CNS using AAVs: the impact of systemic delivery by AAV9 J Saraiva, RJ Nobre, LP de Almeida Journal of Controlled Release 241, 94-109, 2016 | 292 | 2016 |
| Lentiviral-Mediated Delivery of Mutant Huntingtin in the Striatum of Rats Induces a Selective Neuropathology Modulated by Polyglutamine Repeat Size, Huntingtin Expression Levels L Pereira de Almeida, CA Ross, D Zala, P Aebischer, N Deglon The Journal of Neuroscience 22 (9), 3473-3483, 2002 | 275 | 2002 |
| Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation? A Marcelo, R Koppenol, LP de Almeida, CA Matos, C Nóbrega Cell death & disease 12 (6), 592, 2021 | 259 | 2021 |
| Overexpression of the autophagic beclin-1 protein clears mutant ataxin-3 and alleviates Machado–Joseph disease I Nascimento-Ferreira, T Santos-Ferreira, L Sousa-Ferreira, G Auregan, ... Brain 134 (5), 1400-1415, 2011 | 259 | 2011 |
| MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma PM Costa, AL Cardoso, C Custódia, P Cunha, LP De Almeida, ... Journal of Controlled Release 207, 31-39, 2015 | 216 | 2015 |
| Neuroprotective effect of a CNTF-expressing lentiviral vector in the quinolinic acid rat model of Huntington's disease LP de Almeida, D Zala, P Aebischer, N Deglon Neurobiology of disease 8 (3), 433-446, 2001 | 213 | 2001 |
| Allele-specific RNA silencing of mutant ataxin-3 mediates neuroprotection in a rat model of Machado-Joseph disease S Alves, I Nascimento-Ferreira, G Auregan, R Hassig, N Dufour, ... PloS one 3 (10), e3341, 2008 | 210 | 2008 |
| Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model JR Guedes, CM Custodia, RJ Silva, LP de Almeida, MC Pedroso de Lima, ... Human molecular genetics 23 (23), 6286-6301, 2014 | 202 | 2014 |
| Calpastatin-mediated inhibition of calpains in the mouse brain prevents mutant ataxin 3 proteolysis, nuclear localization and aggregation, relieving Machado–Joseph disease AT Simões, N Gonçalves, A Koeppen, N Deglon, S Kügler, CB Duarte, ... Brain 135 (8), 2428-2439, 2012 | 164 | 2012 |
| Machado–Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy CA Matos, LP de Almeida, C Nóbrega Journal of neurochemistry 148 (1), 8-28, 2019 | 162 | 2019 |
| Silencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic mice C Nóbrega, I Nascimento-Ferreira, I Onofre, D Albuquerque, H Hirai, ... PloS one 8 (1), e52396, 2013 | 157 | 2013 |
| Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases J Duarte-Neves, LP de Almeida, C Cavadas Neurobiology of disease 95, 210-224, 2016 | 147 | 2016 |
| Silencing ataxin-3 mitigates degeneration in a rat model of Machado–Joseph disease: no role for wild-type ataxin-3? S Alves, I Nascimento-Ferreira, N Dufour, R Hassig, G Auregan, ... Human molecular genetics 19 (12), 2380-2394, 2010 | 146 | 2010 |
| Role of hypothalamic neurogenesis in feeding regulation L Sousa-Ferreira, LP de Almeida, C Cavadas Trends in Endocrinology & Metabolism 25 (2), 80-88, 2014 | 140 | 2014 |
| Tumor-targeted chlorotoxin-coupled nanoparticles for nucleic acid delivery to glioblastoma cells: a promising system for glioblastoma treatment PM Costa, AL Cardoso, LS Mendonça, A Serani, C Custódia, ... Molecular therapy Nucleic acids 2, 2013 | 134 | 2013 |
Claudia CavadasUniversity Coimbra, Center for Neurosciences and Cell Biology and Faculty of PharmacyVerified email at uc.pt
