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YeonHa Ju
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Severe reactive astrocytes precipitate pathological hallmarks of Alzheimer’s disease via H2O2 production
H Chun, H Im, YJ Kang, Y Kim, JH Shin, W Won, J Lim, Y Ju, YM Park, ...
Nature neuroscience 23 (12), 1555-1566, 2020
2732020
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease
JH Park, YH Ju, JW Choi, HJ Song, BK Jang, J Woo, H Chun, HJ Kim, ...
Science advances 5 (3), eaav0316, 2019
1912019
Astrocytic urea cycle detoxifies Aβ-derived ammonia while impairing memory in Alzheimer’s disease
YH Ju, M Bhalla, SJ Hyeon, JE Oh, S Yoo, U Chae, J Kwon, W Koh, J Lim, ...
Cell Metabolism 34 (8), 1104-1120. e8, 2022
1272022
Platycodin D, a natural component of Platycodon grandiflorum, prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection by hindering membrane fusion
TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ...
Experimental & molecular medicine 53 (5), 956-972, 2021
862021
Revisiting the role of astrocytic MAOB in Parkinson’s disease
MH Nam, M Sa, YH Ju, MG Park, CJ Lee
International journal of molecular sciences 23 (8), 4453, 2022
712022
Astrocytic autophagy plasticity modulates Aβ clearance and cognitive function in Alzheimer’s disease
S Kim, H Chun, Y Kim, Y Kim, U Park, J Chu, M Bhalla, SH Choi, ...
Molecular Neurodegeneration 19 (1), 55, 2024
692024
Activation of astrocytic μ-opioid receptor elicits fast glutamate release through TREK-1-containing K2P channel in hippocampal astrocytes
DH Woo, JY Bae, MH Nam, H An, YH Ju, J Won, JH Choi, EM Hwang, ...
Frontiers in cellular neuroscience 12, 319, 2018
572018
Visualizing reactive astrocyte-neuron interaction in Alzheimer’s disease using 11C-acetate and 18F-FDG
MH Nam, HY Ko, D Kim, S Lee, YM Park, SJ Hyeon, W Won, JI Chung, ...
Brain 146 (7), 2957-2974, 2023
542023
Inhibiting peripheral and central MAO-B ameliorates joint inflammation and cognitive impairment in rheumatoid arthritis
W Won, HJ Choi, JY Yoo, D Kim, TY Kim, YH Ju, KD Park, H Lee, SY Jung, ...
Experimental & Molecular Medicine 54 (8), 1188-1200, 2022
322022
Astrocytes as drivers and disruptors of behavior: new advances in basic mechanisms and therapeutic targeting
D Barnett, K Bohmbach, V Grelot, A Charlet, G Dallérac, YH Ju, J Nagai, ...
Journal of Neuroscience 43 (45), 7463-7471, 2023
222023
Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior
J Won, Y Pankratov, MW Jang, S Kim, YH Ju, S Lee, SE Lee, A Kim, ...
Neuron 110 (3), 423-435. e4, 2022
202022
PyrPeg, a blood–brain-barrier-penetrating two-photon imaging probe, selectively detects Neuritic Plaques, Not Tau Aggregates
JW Choi, YH Ju, Y Choi, SJ Hyeon, CG Gadhe, JH Park, MS Kim, S Baek, ...
ACS Chemical Neuroscience 11 (12), 1801-1810, 2020
152020
Tonic excitation by astrocytic GABA causes neuropathic pain by augmenting neuronal activity and glucose metabolism
YH Ju, J Cho, JY Park, H Kim, EB Hong, KD Park, CJ Lee, E Chung, ...
Experimental & molecular medicine 56 (5), 1193-1205, 2024
142024
Baicalin and baicalein from Scutellaria baicalensis Georgi alleviate aberrant neuronal suppression mediated by GABA from reactive astrocytes
J Cho, EB Hong, YS Kim, J Song, YH Ju, H Kim, H Lee, H Kim, MH Nam
CNS Neuroscience & Therapeutics 30 (5), e14740, 2024
102024
Newly developed reversible MAO-B inhibitor circumvents the shortcomings of irreversible inhibitors in Alzheimer’s disease. Sci Adv. 2019; 5: eaav0316
JH Park, YH Ju, JW Choi, HJ Song, BK Jang, J Woo, H Chun, HJ Kim, ...
9
Platycodin D prevents both lysosome- and TMPRSS2-driven SARS-CoV-2 infection in vitro by hindering membrane fusion
TY Kim, S Jeon, Y Jang, L Gotina, J Won, YH Ju, S Kim, MW Jang, W Won, ...
BioRxiv, 2020.12. 22.423909, 2020
72020
SIRT2 and ALDH1A1 as critical enzymes for astrocytic GABA production in Alzheimer’s disease
M Bhalla, J Joo, D Kim, JI Shin, YM Park, YH Ju, U Park, S Yoo, SJ Hyeon, ...
Molecular Neurodegeneration 20 (1), 6, 2025
62025
Visualizing cancer-originating acetate uptake through monocarboxylate transporter 1 in reactive astrocytes in the glioblastoma tumor microenvironment
D Kim, HY Ko, JI Chung, YM Park, S Lee, SY Kim, J Kim, JH Chun, ...
Neuro-Oncology 26 (5), 843-857, 2024
62024
Visualization of reactive astrocytes in living brain of Alzheimer’s disease patient
MH Nam, HY Ko, S Lee, YM Park, SJ Hyeon, W Won, SY Kim, HH Jo, ...
BioRxiv, 2021.04. 13.439744, 2021
62021
Molecular identification of ALDH1A1 and SIRT2 in the astrocytic putrescine-to-GABA metabolic pathway
M Bhalla, JI Shin, YH Ju, YM Park, S Yoo, HB Lee, CJ Lee
biorxiv, 2023.01. 11.523573, 2023
52023
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Articles 1–20