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David G Broadbent
David G Broadbent
Verified email at msu.edu
Title
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Year
A versatile oblique plane microscope for large-scale and high-resolution imaging of subcellular dynamics
E Sapoznik, BJ Chang, J Huh, RJ Ju, EV Azarova, T Pohlkamp, ES Welf, ...
Elife 9, e57681, 2020
2102020
Metabolic-stress-induced rearrangement of the 14-3-3ζ interactome promotes autophagy via a ULK1-and AMPK-regulated 14-3-3ζ interaction with phosphorylated Atg9
VK Weerasekara, DJ Panek, DG Broadbent, JB Mortenson, AD Mathis, ...
Molecular and cellular biology 34 (24), 4379-4388, 2014
1532014
Quantitative analysis of autophagy reveals the role of ATG9 and ATG2 in autophagosome formation
DG Broadbent, C Barnaba, GI Perez, JC Schmidt
Journal of Cell Biology 222 (7), e202210078, 2023
732023
Roles of NHERF family of PDZ-binding proteins in regulating GPCR functions
D Broadbent, MM Ahmadzai, AK Kammala, C Yang, C Occhiuto, R Das, ...
Advances in immunology 136, 353-385, 2017
332017
AMPK regulates phagophore-to-autophagosome maturation
C Barnaba, DG Broadbent, EG Kaminsky, GI Perez, JC Schmidt
Journal of Cell Biology 223 (8), e202309145, 2024
232024
Systematic analysis of the molecular and biophysical properties of key DNA damage response factors
JR Heyza, M Mikhova, A Bahl, DG Broadbent, JC Schmidt
Elife 12, e87086, 2023
232023
In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein
GI Perez, D Broadbent, AA Zarea, B Dolgikh, MP Bernard, A Withrow, ...
Advanced Genetics 3 (1), 2100055, 2022
192022
A single-objective light-sheet microscope with 200 nm-scale resolution
E Sapoznik, BJ Chang, RJ Ju, ES Welf, D Broadbent, AF Carisey, ...
BioRxiv, 1-40, 2020
152020
Canonical and noncanonical signaling roles of β-arrestins in inflammation and immunity
MM Ahmadzai, D Broadbent, C Occhiuto, C Yang, R Das, H Subramanian
Advances in immunology 136, 279-313, 2017
102017
Tracking the transition from an ATG9A vesicle to an autophagosome
D Broadbent, C Barnaba, JC Schmidt
Autophagy 20 (4), 976-977, 2024
52024
Ubiquitin-mediated recruitment of the ATG9A-ATG2 lipid transfer complex drives clearance of phosphorylated p62 aggregates
DG Broadbent, CM McEwan, D Jayatunge, EG Kaminsky, TM Tsang, ...
Molecular Biology of the Cell 36 (2), ar20, 2025
32025
The PST repeat region of MDC1 is a tunable multivalent chromatin tethering domain
JR Heyza, M Mikhova, GI Perez, DG Broadbent, JC Schmidt
bioRxiv, 2025
32025
Systematic analysis of autophagy identifies Atg9 vesicles as the origin of the phagophore
D Broadbent, C Barnaba, JC Schmidt
bioRxiv, 2022.08. 03.502680, 2022
22022
In vitro and in vivo analysis of microvesicle-mediated metastasis using a bright, red-shifted bioluminescent reporter protein of extracellular vesicles
AA Zarea, GI Perez, D Broadbent, B Dolgikh, MP Bernard, A Withrow, ...
bioRxiv, 2021.07. 23.453512, 2021
22021
The formation of ubiquitin rich condensates triggers recruitment of the ATG9A lipid transfer complex to initiate basal autophagy
DG Broadbent, CM McEwan, TM Tsang, DM Poole, BC Naylor, JC Price, ...
Biorxiv, 2023
2023
Mechanisms of ATG9 mediated aggrephagy initiation
D Madhusanka, C McEwan, D Broadbent, J Schmidt, J Andersen
Cancer Research 83 (7_Supplement), 1383-1383, 2023
2023
Live-Cell Tracking of Autophagy Factors Define the Role of ATG9 and ATG2 in Autophagosome Biogenesis
DG Broadbent
Michigan State University, 2023
2023
ATG9A‐mediated turnover of p62 condensates requires ubiquitin and occurs independently of the LC3‐lipidation machinery
CM McEwan, DG Broadbent, DM Poole, BC Naylor, JC Price, JC Schmidt, ...
The FASEB Journal 36, 2022
2022
In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein (Advanced Genetics 1/03)
GI Perez, D Broadbent, AA Zarea, B Dolgikh, MP Bernard, A Withrow, ...
Advanced Genetics 3 (1), 2270011, 2022
2022
Building the autophagosome: the interplay between WIPI2 and ATG16L1 at the endoplasmic reticulum
C Barnaba, D Broadbent, KR Martin, JP MacKeigan, JC Schmidt
Biophysical Journal 121 (3), 469a, 2022
2022
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Articles 1–20