| Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell D Bonnet, JE Dick Nature medicine 3 (7), 730-737, 1997 | 10049 | 1997 |
| A cell initiating human acute myeloid leukaemia after transplantation into SCID mice T Lapidot, C Sirard, J Vormoor, B Murdoch, T Hoang, J Caceres-Cortes, ... nature 367 (6464), 645-648, 1994 | 6668 | 1994 |
| A human colon cancer cell capable of initiating tumour growth in immunodeficient mice CA O’Brien, A Pollett, S Gallinger, JE Dick Nature 445 (7123), 106-110, 2007 | 5453 | 2007 |
| Cancer stem cells—perspectives on current status and future directions: AACR Workshop on cancer stem cells MF Clarke, JE Dick, PB Dirks, CJ Eaves, CHM Jamieson, DL Jones, ... Cancer research 66 (19), 9339-9344, 2006 | 4179 | 2006 |
| Evolution of the cancer stem cell model A Kreso, JE Dick Cell stem cell 14 (3), 275-291, 2014 | 2800 | 2014 |
| The genetic basis of early T-cell precursor acute lymphoblastic leukaemia J Zhang, L Ding, L Holmfeldt, G Wu, SL Heatley, D Payne-Turner, ... Nature 481 (7380), 157-163, 2012 | 1952 | 2012 |
| Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia LI Shlush, S Zandi, A Mitchell, WC Chen, JM Brandwein, V Gupta, ... Nature 506 (7488), 328-333, 2014 | 1796 | 2014 |
| Targeting of CD44 eradicates human acute myeloid leukemic stem cells L Jin, KJ Hope, Q Zhai, F Smadja-Joffe, JE Dick Nature medicine 12 (10), 1167-1174, 2006 | 1632 | 2006 |
| Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry DR Bandura, VI Baranov, OI Ornatsky, A Antonov, R Kinach, X Lou, ... Analytical chemistry 81 (16), 6813-6822, 2009 | 1512 | 2009 |
| Stem cell concepts renew cancer research JE Dick Blood, The Journal of the American Society of Hematology 112 (13), 4793-4807, 2008 | 1497 | 2008 |
| Hematopoiesis: a human perspective S Doulatov, F Notta, E Laurenti, JE Dick Cell stem cell 10 (2), 120-136, 2012 | 1374 | 2012 |
| Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity KJ Hope, L Jin, JE Dick Nature immunology 5 (7), 738-743, 2004 | 1358 | 2004 |
| Stem cell gene expression programs influence clinical outcome in human leukemia K Eppert, K Takenaka, ER Lechman, L Waldron, B Nilsson, P Van Galen, ... Nature medicine 17 (9), 1086-1093, 2011 | 1287 | 2011 |
| Purification of primitive human hematopoietic cells capable of repopulating immune-deficient mice M Bhatia, JCY Wang, U Kapp, D Bonnet, JE Dick Proceedings of the national academy of Sciences 94 (10), 5320-5325, 1997 | 1232 | 1997 |
| Isolation of single human hematopoietic stem cells capable of long-term multilineage engraftment F Notta, S Doulatov, E Laurenti, A Poeppl, I Jurisica, JE Dick Science 333 (6039), 218-221, 2011 | 1208 | 2011 |
| Identification of primitive human hematopoietic cells capable of repopulating NOD/SCID mouse bone marrow: implications for gene therapy A Larochelle, J Vormoor, H Hanenberg, JCY Wang, M Bhatia, T Lapidot, ... Nature medicine 2 (12), 1329-1337, 1996 | 1012 | 1996 |
| Distinct routes of lineage development reshape the human blood hierarchy across ontogeny F Notta, S Zandi, N Takayama, S Dobson, OI Gan, G Wilson, ... Science 351 (6269), aab2116, 2016 | 1011 | 2016 |
| Prediction of acute myeloid leukaemia risk in healthy individuals S Abelson, G Collord, SWK Ng, O Weissbrod, N Mendelson Cohen, ... Nature 559 (7714), 400-404, 2018 | 992 | 2018 |
| A 17-gene stemness score for rapid determination of risk in acute leukaemia SWK Ng, A Mitchell, JA Kennedy, WC Chen, J McLeod, N Ibrahimova, ... Nature 540 (7633), 433-437, 2016 | 975 | 2016 |
| Variable clonal repopulation dynamics influence chemotherapy response in colorectal cancer A Kreso, CA O'Brien, P Van Galen, OI Gan, F Notta, AMK Brown, K Ng, ... Science 339 (6119), 543-548, 2013 | 937 | 2013 |
