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Andrew D. Southam
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High-throughput tissue extraction protocol for NMR-and MS-based metabolomics
H Wu, AD Southam, A Hines, MR Viant
Analytical biochemistry 372 (2), 204-212, 2008
7432008
Dynamic range and mass accuracy of wide-scan direct infusion nanoelectrospray Fourier transform ion cyclotron resonance mass spectrometry-based metabolomics increased by the …
AD Southam, TG Payne, HJ Cooper, TN Arvanitis, MR Viant
Analytical chemistry 79 (12), 4595-4602, 2007
2432007
Metabolic engineering against the arginine microenvironment enhances CAR-T cell proliferation and therapeutic activity
L Fultang, S Booth, O Yogev, B Martins da Costa, V Tubb, S Panetti, ...
Blood, The Journal of the American Society of Hematology 136 (10), 1155-1160, 2020
1862020
A complete workflow for high-resolution spectral-stitching nanoelectrospray direct-infusion mass-spectrometry-based metabolomics and lipidomics
AD Southam, RJM Weber, J Engel, MR Jones, MR Viant
Nature protocols 12 (2), 310-328, 2017
1832017
Birmingham Metabolite Library: a publicly accessible database of 1-D 1H and 2-D 1H J-resolved NMR spectra of authentic metabolite standards (BML-NMR)
C Ludwig, JM Easton, A Lodi, S Tiziani, SE Manzoor, AD Southam, ...
Metabolomics 8 (1), 8-18, 2012
1732012
A new approach to toxicity testing in Daphnia magna: application of high throughput FT-ICR mass spectrometry metabolomics
NS Taylor, RJM Weber, AD Southam, TG Payne, O Hrydziuszko, ...
Metabolomics 5 (1), 44-58, 2009
1572009
Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics
EG Armitage, AD Southam
Metabolomics 12 (9), 146, 2016
1452016
Characterization of isotopic abundance measurements in high resolution FT-ICR and Orbitrap mass spectra for improved confidence of metabolite identification
RJM Weber, AD Southam, U Sommer, MR Viant
Analytical chemistry 83 (10), 3737-3743, 2011
1392011
International ring trial of a high resolution targeted metabolomics and lipidomics platform for serum and plasma analysis
JW Thompson, KJ Adams, J Adamski, Y Asad, D Borts, JA Bowden, ...
Analytical chemistry 91 (22), 14407-14416, 2019
1092019
Metabolomics reveals target and off-target toxicities of a model organophosphate pesticide to roach (Rutilus rutilus): implications for biomonitoring
AD Southam, A Lange, A Hines, EM Hill, Y Katsu, T Iguchi, CR Tyler, ...
Environmental science & technology 45 (8), 3759-3767, 2011
942011
A signal filtering method for improved quantification and noise discrimination in fourier transform ion cyclotron resonance mass spectrometry-based metabolomics data
TG Payne, AD Southam, TN Arvanitis, MR Viant
Journal of the American Society for Mass Spectrometry 20 (6), 1087-1095, 2009
892009
Drug redeployment to kill leukemia and lymphoma cells by disrupting SCD1-mediated synthesis of monounsaturated fatty acids
AD Southam, FL Khanim, RE Hayden, JK Constantinou, KM Koczula, ...
Cancer research 75 (12), 2530-2540, 2015
772015
Metabolic changes in flatfish hepatic tumours revealed by NMR-based metabolomics and metabolic correlation networks
AD Southam, JM Easton, GD Stentiford, C Ludwig, TN Arvanitis, MR Viant
Journal of proteome research 7 (12), 5277-5285, 2008
732008
Assessment of human plasma and urine sample preparation for reproducible and high-throughput UHPLC-MS clinical metabolic phenotyping
AD Southam, LD Haglington, L Najdekr, A Jankevics, RJM Weber, ...
Analyst 145 (20), 6511-6523, 2020
562020
Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
DJ Wilcock, AP Badrock, CW Wong, R Owen, M Guerin, AD Southam, ...
Cell reports 39 (12), 2022
452022
Probing the action of a novel anti-leukaemic drug therapy at the single cell level using modern vibrational spectroscopy techniques
JL Denbigh, D Perez-Guaita, RR Vernooij, MJ Tobin, KR Bambery, Y Xu, ...
Scientific Reports 7 (1), 2649, 2017
402017
Distinguishing between the metabolome and xenobiotic exposome in environmental field samples analysed by direct-infusion mass spectrometry based metabolomics and lipidomics
AD Southam, A Lange, R Al-Salhi, EM Hill, CR Tyler, MR Viant
Metabolomics 10 (6), 1050-1058, 2014
392014
Metabolomics reveal potential natural substrates of AcrB in Escherichia coli and Salmonella enterica Serovar Typhimurium
X Wang-Kan, G Rodríguez-Blanco, AD Southam, CL Winder, WB Dunn, ...
MBio 12 (2), 10.1128/mbio. 00109-21, 2021
352021
Disruption of DNA Methylation via S-Adenosylhomocysteine Is a Key Process in High Incidence Liver Carcinogenesis in Fish
L Mirbahai, AD Southam, U Sommer, TD Williams, JP Bignell, BP Lyons, ...
Journal of proteome research 12 (6), 2895-2904, 2013
342013
Characterization of monophasic solvent-based tissue extractions for the detection of polar metabolites and lipids applying ultrahigh-performance liquid chromatography–mass …
AD Southam, H Pursell, G Frigerio, A Jankevics, RJM Weber, WB Dunn
Journal of proteome research 20 (1), 831-840, 2020
302020
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Articles 1–20